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Chapter 084. Head and Neck Cancer (Part 3)

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Table 84-1 TNM Classification for Head and Neck Cancer (Except Nasopharyngeal) Primary Tumor Site T Grade Oropharynx Hypopharynx T1 0–2 cm 0–2 cm T2 2.1–4 cm 1 site, 2–4 cm T3 4 cm 4 cm T4a Larynx, muscle of tongue, Thyroid/cricoid cartilage, medial pterygoid, hard palate, hyoid mandible invasion bone, thyroid or gland, central esophagus, compartment soft tissue invasion T4b Lateral pterygoid muscle, pterygoid plates, Invasion of prevertebral lateral fascia, encases carotid artery, or nasopharynx, or skull base or involves mediastinal structures encases carotid artery invasion Regional Lymph Nodes (N) NX Regional lymph nodes cannot be assessed N0 No regional lymph node metastasis N1 Unilateral metastasis in lymph node(s), ≤6 cm in greatest dimension, above the supraclavicular fossa N2 ...

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  1. Chapter 084. Head and Neck Cancer (Part 3) Table 84-1 TNM Classification for Head and Neck Cancer (Except Nasopharyngeal) Primary Tumor Site T Oropharynx Hypopharynx Grade T1 0–2 cm 0–2 cm T2 2.1–4 cm >1 site, 2–4 cm T3 >4 cm >4 cm T4a Larynx, muscle of tongue, Thyroid/cricoid cartilage,
  2. medial pterygoid, hard palate, hyoid bone, thyroid gland, mandible invasion esophagus, or central compartment soft tissue invasion T4b Lateral pterygoid muscle, Invasion of prevertebral pterygoid plates, lateral fascia, encases carotid artery, or nasopharynx, or skull base or involves mediastinal structures encases carotid artery invasion Regional Lymph Nodes (N) NX Regional lymph nodes cannot be assessed N0 No regional lymph node metastasis N1 Unilateral metastasis in lymph node(s), ≤6 cm in greatest dimension, above the supraclavicular fossa N2 Bilateral metastasis in lymph node(s), ≤6 cm in greatest dimension, above the supraclavicular fossa
  3. N3 Metastasis in a lymph node(s) >6 cm and/or to supraclavicular fossa N3a > 6 cm N3b Extension to the supraclavicular fossa MX Distant metastasis cannot be assessed M0 No distant metastasis M1 Distant metastasis Stage Grouping Stage Tis N0 M0 0 Stage T1 N0 M0 I
  4. Stage T2 N0 M0 II Stage T3 N0 M0 III T1 N1 M0 T2 N1 M0 T3 N1 M0 Stage T4a N0 M0 IVA T4a N1 M0 T1 N2 M0 T2 N2 M0
  5. T3 N2 M0 T4a N2 M0 Stage T4b Any N M0 IVB Any T N3 M0 Stage Any T Any N M1 IVC
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