CLINICAL PHARMACOLOGY 2003 (PART 14)

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CLINICAL PHARMACOLOGY 2003 (PART 14)

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Lesser categories of (3-lactams include — carbapenems (e.g. meropenem) — monobactams (e.g. aztreonam) and — p-lactamase inhibitors (e.g. clavulanic acid). Other inhibitors of cell wall synthesis include vancomycin and teicoplanin. INHIBITION OF PROTEIN SYNTHESIS Aminoglycosid.es. The names of those that are derived from streptomyces end in 'mycin', e.g. tobramycin. Others include gentamicin (from Micromonospora purpurea which is not a fungus, hence the spelling as 'micin') and semisynthetic drugs, e.g. amikacin. Tetracyclines as the name suggests are four-ringed structures and their names end in '-cycline'. Macrolides: e.g. erythromycin. Clindamycin, structurally a lincosamide, has a similar action and overlapping antibacterial activity....

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