CLINICAL PHARMACOLOGY 2003 (PART 19)

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CLINICAL PHARMACOLOGY 2003 (PART 19)

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But pain is perfect misery, the worst Of evils, and, excessive, overturns All patience. (John Milton, 1608-1674, Paradise Lost) tissue damage, or described in terms of such damage.1 It is mediated by specific nerve fibres to the brain where its conscious appreciation may be modified by various factors. The word 'unpleasant' comprises the whole range of disagreeable feelings from being merely inconvenienced to misery, anguish, anxiety, depression and desperation, to the ultimate cure of suicide.2,3 • Analgesic drug: a drug that relieves pain due to multiple causes, e.g. paracetamol, morphine. ...

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