Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 4)

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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 4)

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Introduction: Small amount of drugs and poisons incorporated into human bodies are hidden among large amounts of biological components, such as proteins, lipids, nucleic acids and membranes. It is not easy to detect only a target compound from such complicated matrices. Before instrumental analysis, extraction procedure is usually essential and very important. Extraction methods are used for removal of such proteins and lipids existing in large amounts in biological matrices, for removal of impurity compounds interfering with chromatographic separation, for condensation of a target compound, and for removal of compounds causing troubles (such as obstruction of chromatographic columns and contamination...

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