Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 53)

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Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 53)

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Introduction: Japanese people are very fond of eating fugu (puffer) fishes (especially Takifugu rubripes) as a feast especially in the winter season. However, the fish contains highly poisonous toxin tetrodotoxin (TTX) especially in its liver and ovary. Therefore, the number of fugu (puffer) fish poisoning incidents in Japan were 554, in which 912 people were poisoned during 20 years in 1980–1999; among the 912 people, 106 subjects were fatal (mortality rate, 11.6 %) ( Table 3.1)a. However, in recent 10 years, its incidence has been reduced to about half due to the improvement of early life-saving systems in emergency...

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