HPLC for Pharmaceutical Scientists 2007 (Part 7A)

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HPLC for Pharmaceutical Scientists 2007 (Part 7A)

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The discovery of a new drug is a challenging task that includes (a) identifica- tion of a biochemical target for certain diseases and (b) screening of a large number of compounds from libraries of compounds arising from synthetic chemistry, combinatorial chemistry, and natural product isolation for lead gen- eration. The lead compound is then optimized based on biological activity, selectivity, pharmacokinetic property, and metabolism.

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