Administration of drugs

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  • Tham khảo sách 'the acquisition of drugs and biologics for chemical and biological warfare defense', khoa học xã hội, lịch sử văn hoá phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

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  • Introduction: Phenothiazine drugs, including chlorpromazine and levomepromazine, have been being widely used as neuroleptics (major tranquilizers), antiparkinsonian drugs and antihistaminics for a long time [1]. Table 1.1 shows chemical structures of representative phenothiazines. These drugs show blocking action on D2 receptors of dopaminergic neurons; there is close relationship between the receptor blocking and tranquilizing actions. The dopamine D2 receptor-blocking actions provoke extrapyramidal symptoms, such as muscular stiffness, tremor and ptyalism.

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  • Clinical Implications of Altered Bioavailability Some drugs undergo near-complete presystemic metabolism and thus cannot be administered orally. Nitroglycerin cannot be used orally because it is completely extracted prior to reaching the systemic circulation. The drug is therefore used by the sublingual or transdermal routes, which bypass presystemic metabolism. Some drugs with very extensive presystemic metabolism can still be administered by the oral route, using much higher doses than those required intravenously.

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  • Clinical Implications of Drug Distribution Digoxin accesses its cardiac site of action slowly, over a distribution phase of several hours. Thus, after an intravenous dose, plasma levels fall, but those at the site of action increase over hours. Only when distribution is near-complete does the concentration of digoxin in plasma reflect pharmacologic effect. For this reason, there should be a 6–8 h wait after administration before plasma levels of digoxin are measured as a guide to therapy.

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  • Diagnosis and Treatment of Adverse Drug Reactions The manifestations of drug-induced diseases frequently resemble those of other diseases, and a given set of manifestations may be produced by different and dissimilar drugs. Recognition of the role of a drug or drugs in an illness depends on appreciation of the possible adverse reactions to drugs in any disease, on identification of the temporal relationship between drug administration and development of the illness, and on familiarity with the common manifestations of the drugs.

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: In-vivo evaluation of simultaneous administration of incompatible drugs in a central venous catheter with a decreased port to port distance...

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  • The need for a book such as this one has arisen as a result of recent changes in legislation and expansion in the numbers of health care professionals involved in administration and/or prescription of medicines. The book is an introduction to pharmacology for health care professionals. Although anyone involved in the care of patients is a health care professional, this book has been specifically written for physiotherapists, podiatrists and radiographers (otherwise known as allied health professionals). However, the book may be of interest to other health care professionals....

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  • However, these events are but the immediate manifestation of a continuing dependent relationship that involves three types of interactions: licensing CBW drugs and biologics, especially vaccines; using Investigational New Drugs in military combat (and other special situations); and ensuring the compliance of producers with manufacturing requirements. DoD has not been well organized to respond to FDA. This report proposes various education and training programs that should be initiated for all defense personnel engaged in the development or acquisition of drugs and biologics for CBW defense.

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  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Regression of sporadic intra-abdominal desmoid tumour following administration of non-steroidal anti-inflammatory drug

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  • "In China, illicit drug use is an administrative offense and Chinese law dictates that drug users 'must be rehabilitated.' In reality, police raids on drug users often drive them underground, away from methadone clinics, needle exchange sites, and other proven HIV prevention services. And every year Chinese policy send tens of thousands of drug users to mandatory frug treatment centers, often for years, without trial or due process" -- p. [4] of cover.An Unbreakable CycleDrug Dependency Treatment, Mandatory Confinement, and HIV/AIDSin China’s Guangxi ProvinceI. Executive Summary ...........

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  • Purpose: Based on theoretical studies of state management on the prevention of drugs, analysis and assessment of the state of the state management on the prevention of drugs in Vietnam, fellows establish and implement the scientific foundation to propose practical solutions to improve system ef ciency of state management on the prevention of drugs in Vietnam during the integration period.

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  • Chapter 14 - Venous access and medication administration. In this chapter you will learn about the following: Convert selected units of measurement into the household, apothecary, and metric systems; identify the steps in the calculation of drug dosages; calculate the correct volume of drug to be administered in a given situation;...

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  • Drug Administration be very precise. (Standardized medicinal teaspoons and tablespoons are available.) Eye drops and nose drops (A) are designed for application to the mucosal surfaces of the eye (conjunctival sac) and nasal cavity, respectively. In order to prolong contact time, nasal drops are formulated as solutions of increased viscosity. Solid dosage forms include tablets, coated tablets, and capsules (B). Tablets have a disk-like shape, produced by mechanical compression of active substance, filler (e.g., lactose, calcium sulfate), binder, and auxiliary material (excipients).

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  • This Institute of Medicine/National Research Council report was written in response to a congressional request that the U.S. Food and Drug Administration (FDA) contract with the National Academies for a comprehensive study of gaps in public health protection provided by the food safety system in the United States. In particular, the study was to review the role of the FDA in ensuring the safety of the nation’s food supply.

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  • Background Definitions Causation: degrees of certainty Pharmacovigilance and pharmacoepidemiology Classification Causes Allergy in response to drugs Effects of prolonged administration: chronic organ toxicity Adverse effects on reproduction Background Cur'd yesterday of my disease I died last night of my physician.1 Nature is neutral, i.e. it has no 'intentions' towards humans, though it is often unfavourable to them.

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  • As Christine Ammer notes, the underlying assumption of The Encyclopedia of Women’s Health, her classic and concise reference for women’s health, is that “every woman wants to take responsibility for her own health.” By helping us understand how our bodies work, the marvel of our bodies’ normal functions and the profound consequences of its malfunctions, and the care and treatments available to us, she helps us to take charge of our own health.

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  • Agree that in consideration of and as a condition of acceptance of my participation in the Event, for myself, my executors and administrators, hereby waive all and any claim, right or cause of action against the Council which I or they might otherwise have, arising out of my injury or loss of any description whatsoever which I may suffer or sustain in the course of or consequence upon my participation or participation in the Event. Understand that while participating in the Event, I agree to abide by any rules; participate with care for other participants and members of the general...

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  • Introduction: As coumarin rodenticides, warfarin, coumatetralyl, coumafuryl, coumachlor and bromadiolone are commercially available in Japan. The coumarin rodenticides do not show direct anticoagulant action causing bleeding, but inhibit the metabolic cycle of vitamin K; the inhibition causes the interference with protein biosynthesis of vitamin K-dependent coagulant factors (II, VII, IX and X factors) in the liver, which are very important for the blood coagulation system. The lowered coagulant factors cause the bleeding deaths of the rodents [1].

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  • Despite massive efforts in drug discovery fueled by combinatory chemistry, recombinant DNA technology, and highthroughput screening, surprisingly few molecules make it through the drug development process. While the reasons are debated, it is certain that many new chemical entities (NCEs) suffer from recurring problems that hinder development— low water solubility, instability, or inadequate pharmacokinetics. An estimated 43% of NCEs are poorly water-soluble.

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  • This Handbook of Police Administration, co-edited by Jim Ruiz and Don Hummer, provides a smorgasbord of topics that are at the coalface of policing: the difficulties police encounter dealing with drug problems, traffic issues, race and ethnicity challenges, and street gang problems. Cross-cutting themes such as leadership in policing, use of force, and understanding how the law shapes (or fails to shape) police practice are relevant to students of police studies, practitioners, and scholars alike.

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