Some people believe that if cancer has spread
to other parts of the body (called metastatic
cancer), it is the same as advanced cancer. This
is not necessarily true. You can have widespread
cancer, but it can still be treatable and sometimes
curable. Examples of this are testicular cancer and
certain types of leukemia and lymphoma.
It is my privilege to introduce this Handbook on Advanced Cancer Care,
which belongs to a series of publications initiated by the European Society
for Medical Oncology (ESMO). There is a great need, especially for medical
oncologists, to have a comprehensive overview of the essential elements
needed for the care of patients with advanced cancer. This handbook fulfills
The Handbook on Advanced Cancer Care provides useful definitions and
surveys of treatment principles.
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Caregiver assessment of patients with advanced cancer: concordance with patients, effect of burden and positivity
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: A novel combination of Chinese medicines to treat advanced cancers and lymphomas in rats...
For decades we have been learning about the interplay between tumors and the
immune system. Our knowledge seemed somewhat incomplete and indirect, like
listening to the ocean waves through a shell. Only recently, cancer immunotherapy has
started to become a reality, with Provenge (Dendreon Corporation, WA), an
autologous antigen-presenting cell preparation, earning the approval of United States
Food and Drug Administration (FDA) for the treatment of advanced prostate cancer in
Remarkable advances in medical diagnostic imaging have been made during the past
few decades. The development of new imaging techniques and continuous
improvements in the display of digital images have opened new horizons in the study
of brain anatomy and pathology. The field of brain imaging has now become a fast-
moving, demanding, and exciting multidisciplinary activity. I hope that this textbook
will be useful to students and clinicians in the field of neuroscience, in understanding
the fundamentals of advances in brain imaging.
Lung cancer is the leading cause of cancer death among men and women in
the United States with 170,000 deaths per year. This exceeds the sum of the
next three leading causes of death due to cancer: breast, colon, and prostate.
There are over 1 million deaths worldwide due to lung cancer, making it truly
an epidemic. Fewer than 15% achieve a 5-yr survival. The vast majority (85%)
present with advanced disease, although stage I patients may have a 5-yr
survival approaching 70% (1).
Over the past 20 years, technological advances in molecular biology have
proven invaluable to the understanding of the pathogenesis of human cancer.
The application of molecular technology to the study of cancer has not only
led to advances in tumor diagnosis, but has also provided markers for the
assessment of prognosis and disease progression. The aim of Molecular Analysis
of Cancer is to provide a comprehensive collection of the most up-to-date
techniques for the detection of molecular changes in human cancer.
Since the first edition of Breast Cancer: Prognosis, Treatment and Prevention was
published there has been a tremendous amount of new information related to the basic
and clinical applications of this disease which can affect 1 of 8 people in the USA and
1 of 12 in European countries.
Prostate cancer is one of the most common types of cancer in men and its treatment was constricted to surgery for confined state and androgen ablation for advanced disease until new options have become available. The present book covers a broad range of novel aspects of prostate cancer diagnosis, treatment and patient care, as well as new research on relevant cell biology.
There is growing evidence on the importance of studies focusing on mechanisms and
strategies leading to cancer prevention. The plethora of approaches include regulation
of oxidative stress using antioxidant therapies, carefully balanced diets and living
habits, epidemiological evidence and molecular approaches on the role of key
biological molecules such as antioxidant enzymes, vitamins, proteins and naturally
occurring free radical scavengers as well as controversial results and clinical
applications. These are some of the topics that this book highlights.
Head and Neck Cancer: Treatment Patients with head and neck cancer can be categorized into three clinical groups: those with localized disease, those with locally or regionally advanced disease, and those with recurrent and/or metastatic disease. Comorbidities associated with tobacco and alcohol abuse can affect treatment outcome and define long-term risks for patients who are cured of their disease.
Nearly one-third of patients have localized disease; that is, T1 or T2 (stage I or stage II) lesions without detectable lymph node involvement or distant metastases.
A clustering of the disease among close
relatives has also been shown, although there is no consensus on which inheritable
genetic defects are involved. In spite of extensive research, reliable findings on risk factors
relating to lifestyle, diet or the environment remain elusive. Possible lifestyle risk factors
are high intakes of α-linolenic acid (a polyunsaturated fatty acid in vegetables and dairy
products) and calcium.
The field of general surgery has changed dramatically over the last
ten years with the acceptance of laparoscopy as an extension of the scalpel.
Once ridiculed by most academic centers, laparoscopy has revolutionized
the management of biliary tract disease and has led to a critical
reassessment of how patients with other general surgical problems are
managed. The rapid advancement and acceptance of laparoscopy as a
part of general surgery is apparent today since most academic centers
have laparoscopic sections and many offer laparoscopic fellowships....
“Advances in Prostate Cancer” is an addition to the InTech collection of three previous
books about prostate cancer and aims at providing a comprehensive overview of specific
aspects of the latest research and current knowledge relating to this tumor entity to
scientists and clinicians. For this purpose a series of research articles, clinical investigations
and reviews that deal with a wide range of relevant aspects pertinent to the epidemiology,
diagnosis, patient care, treatment and basic biology of prostate cancer were included.
There have been a significant number of advances
in the field of cancer research since the
first edition of Cancer Biology, which was published
in 1981. These include advances in defining
the genetic and phenotypic changes in cancer
cells, the genetic susceptibility to cancer, molecular
imaging to detect smaller and smaller tumors,
the regulation of gene expression, and the
‘‘-omics’’ techniquesofgenomics, proteomics,and
metabolomics, among others.
The last three decades have witnessed tremendous advances in the understanding
and treatment of breast cancer. As a result, starting shortly before the 1990s, a persistent
decrease in breast cancer mortality has been documented, primarily in the
United States and in several European countries. Breast cancer, however, remains
an important health problem. In this book, which is mainly dedicated to nuclear
medicine, experts have thoroughly reviewed the achievements made in the diagnosis,
monitoring and treatment of this disease.
Today, cancer research is focused on determining how genome and proteome level
information may be useful as tools in prevention, diagnosis, and prognosis. The
development of “omics” technologies, such as proteomics and transcriptomics has
opened new research areas for scientists working on cancer research.
Pancreatic Cancer: Treatment Symptoms and the associated impaired performance status are significant issues in the management of patients with pancreatic cancer, as they can have a marked negative impact on the ability to safely deliver chemotherapy or perform curative surgery. For example, patients with malabsorption secondary to pancreatic insufficiency may be treated with pancreatic enzyme supplementation. Indeed effective symptom management is as important a therapeutic goal as survival prolongation.
This uncommon type of skin cancer develops from neuroendocrine cells (hormone-making
cells that resemble nerve cells in some ways) in the skin. They are most often found on the
head, neck, and arms but can start anywhere.
These cancers are thought to be caused in part by sun exposure and in part by Merkel cell
polyomavirus (MCV). About 8 out of 10 Merkel cell carcinomas are thought to be related to
MCV infection. MCV is a common virus. Many people are infected with MCV, but it usually
causes no symptoms. In a small portion of people with this infection,...