Advanced molecular

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  • Molecular dynamics (MD) simulations have played increasing roles in our understanding of physical and chemical processes of complex systems and in advancing science and technology. Over the past forty years, MD simulations have made great progress from developing sophisticated theories for treating complex systems to broadening applications to a wide range of scientific and technological fields. The chapters of Molecular Dynamics are a reflection of the most recent progress in the field of MD simulations....

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  • Plant response to reduced water availability and other abiotic stress (e.g. metals) have been analysed through changes in water absorption and transport mechanisms and also by molecular and genetic approach. A relatively new aspects of fruit nutrition are presented in order to provide the basis for the improvement of some fruit quality traits. The involvement of hormones, nutritional and proteomic plant profiles together with some structure/function of sexual components have also been addressed.

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  • A global research community of scientists is teasing out the biochemical mechanisms that regulate normal cellular physiology in a variety of organisms. Much of current research aims to understand the network of molecular reactions that regulate cellular homeostasis, and to learn what allows cells to sense stress and activate appropriate biochemical responses.

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  • A better understanding of the influence of tobacco smoke on the host response to periodontal infection has been the major concern in numerous studies whereas, limited research has been published aiming to identify the influence of tobacco smoke on the dental biofilm. Tobacco smoke has been shown to cause shifts in the microbial species that comprise dental plaque (Haffajee & Socransky 2001, Kamma et al. 1999, Shiloah et al. 2000, Umeda et al. 1998, van Winkelhoff et al. 2001, Zambon et al. 1996). In a recent study by our group (Buduneli et al.

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  • Biotechnology is the scientific field of studying and applying the most efficient methods and techniques to get useful end-products for the human society by using viable micro-organisms, cells, and tissues of plants or animals, or even certain functional components of their organisms, that are grown in fully controlled conditions to maximize their specific metabolism inside fully automatic bioreactors.

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  • In the mid-1990s plant biotechnology burst onto the scene in world agriculture, beginning a second ‘green revolution’ and precipitating one of the great public debates of our time. Approximately a decade later, this book describes the impact of genetically modified (GM) crops on world agriculture, recent advances in the technology and the areas of research from which the next generation of GM crops is likely to emerge, as well as addresses the issues of safety and regulation that have dogged the technology, particularly in Europe.

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  • This book addresses the evolutionary stage of Chemical Engineering and provides an overview to the state of the art and technological advancements. Chemical Engineering applications have always been challenging. Optimization of plausible solutions to problems in economic manner through technology is worth. The script has been designed to enable the reader to access the desired knowledge on fundamentals and advancements in Chemical Engineering in a single text.

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  • The book "Intraepithelial neoplasia" is till date the most comprehensive book dedicated entirely to preinvasive lesions of the human body. Created and published with an aim of helping clinicians to not only diagnose but also understand the etiopathogenesis of the precursor lesions, the book also attempts to identify its molecular and genetic mechanisms. All of the chapters contain a considerable amount of new information, with an updated bibliographical list as well as the latest WHO classification of intraepithelial lesions that has been included wherever needed.

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  • During the last three decades, important advances have been made in the available treatments for the loss of skeletal tissue as a result of trauma or disease. The application of large skeletal allografts and total joint replacement have become successful and reproducible treatment options. Unfortunately there still is a significant incidence of failure because of mechanical or biological complications.

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  • After the first edition published in 2007 that became a best seller, the continuous scientific developments in the field have prompted us to produce the second edition of this book. As it happens in life and science, some of the novel and promising data presented in the first edition have been confirmed, some not, and new breakthrough achievements have been accomplished. Stem Cells in Reproductive Medicine, Basic Science and Therapeutic Potential, second edition, updates the revolutionary advances in stem cell science that may potentially impact on human reproductive medicine.

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  • For otolaryngology–head and neck surgeons in training as residents and fellows, it is a difficult task to keep up with all of the advances in the basic and clinical sciences that impact the medical and surgical practice of their specialty. It is also pertinent to the practice of otolaryngology–head and neck surgery for interested medical students and lecturers in medical school faculties who teach students and resident physicians to have a reference book that clearly presents the basic principles.

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  • Advanced Computer-Assisted Techniques in Drug Discovery edited by Han van de Waterbeemd .Methods and Principles in Medicinal Chemistry Edited by R. Mannhold P. Krogsgaard-Larsen H. Timmerman Volume 1 Hugo Kubinyi, QSAR: Hansch Analysis and Related Approaches Volume 2 Han van de Waterbeemd (ed.), Chemometric Methods in Molecular Design Volume 3 Han van de Waterbeemd (ed.), Advanced Computer- Assisted Techniques in Drug Discovery .Methods and Principles in Medicinal Chemistry edited by R. Mannhold, P. Krogsgaard-Larsen, H.

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  • Tools shape how we think; when the only tool you have is an axe, everything resembles a tree or a log. The rapid advances in instrumentation in the last decade, which allow us to measure and manipulate individual molecules and structures on the nanoscale, have caused a paradigm shift in the way we view molecular behavior and surfaces. The microscopic details underlying interfacial phenomena have customarily been inferred from in situ measurements of macroscopic quantities. Now we can see and “finger” physical and chemical processes at interfaces.

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  • Science progresses by a symbiotic interaction between theory and experiment: theory is used to interpret experimental results and may suggest new experiments; experiment helps to test theoretical predictions and may lead to improved theories. Theoretical Chemistry (including Physical Chemistry and Chemical Physics) provides the concep- tual and technical background and apparatus for the rationalisation of phenomena in the chemical sciences. It is, therefore, a wide ranging subject, reflecting the diversity of molecular and related species and processes arising in chemical systems.

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  • In the second part, all chapters refer to the latest advances in microbial biotechnology to be used in recombinant protein production as well as heterologous protein biosynthesis. The chapters included in the third section are focused on recent achievements in molecular biotechnology and genetic engineering. In the final section, the chapters emphasize the main scientific results that were accomplished in tissue engineering as an important biotechnological tool in medicine and health care. ...

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  • Advanced Topics in Biomineralization is a compendium of current topics focusing on processes of formation, organization, as well as mineralization of novel structural materials. From enchondral ossification to the application of biomineralized cement, the subject of biomineralization encompasses a range of diverse disciplines including molecular biology, supramolecular chemistry, materials science and engineering. A common theme in all these areas of research in biomineralization is the ability to utilize strategies from Nature to create functional materials.

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  • Numerous authors proposed chapters on their work, and those presented here are the fruit of those proposals. As editor of this book, it has been my pleasure to collaborate with these many, fine contributing scientists. This text brings forth a great amount of fresh information on the biogeography and ecology of poorly known taxa and landscapes, and explores biogeographic processes not previously studied. The assembled work is an anthology of issues in modern biogeography, with topics ranging across regional to global spatial scales, and ecological to evolutionary temporal scales.

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  • Lung cancer is the leading cause of cancer death among men and women in the United States with 170,000 deaths per year. This exceeds the sum of the next three leading causes of death due to cancer: breast, colon, and prostate. There are over 1 million deaths worldwide due to lung cancer, making it truly an epidemic. Fewer than 15% achieve a 5-yr survival. The vast majority (85%) present with advanced disease, although stage I patients may have a 5-yr survival approaching 70% (1).

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  • Since this book was first published in 1993, the Advanced Paediatric Life Support (APLS) concept and courses have gone a great way towards their aim of bringing simple guidelines for the management of ill and injured children to front-line doctors and nurses. Over the years an increasing number of experts have contributed to the work and we extend our thanks both to them and also to our instructors who unceasingly provide helpful feedback.The Advanced Paediatric Life Support Course is now well established in several countries outside the United Kingdom.

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  • The third edition of Principles of Tissue Engineering attempts to incorporate the latest advances in the biology and design of tissues and organs and simultaneously to connect the basic sciences — including new discoveries in the field of stem cells — with the potential application of tissue engineering to diseases affecting specific organ systems.

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