Allergen isoforms

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  • The present edition of "Current Insights in Pollen Allergens" provides recent aspects related to pollen allergy, a major medical problem which is still under thorough studies. The chapters of this book will be of significant value to those interested to get notions about molecular basis of pollen allergy, such as allergen proteins polymorphism and its implications in allergic disease, cross-reactivity between pollen and pollen-plant food derived allergens, as well as strategies for clinical trial and future research....

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:Changes in the expression of NO synthase isoforms after ozone: the effects of allergen exposure...

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  • Hyaluronidase (E.C., one of the three major allergens of yellow jacket venom, is a glycoprotein of 45 kDa that is largely responsible for the cross-reactivity of wasp and bee venoms with sera of allergic patients. The asparagine-linked carbohydrate often appears to constitute the com-mon IgE-binding determinant.

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  • Until now, only a small amount of information is available about tomato allergens. In the present study, a glycosylated allergen of tomato (Lycopersicon esculentum), Lyc e 2, was purified from tomato extract by a two-step FPLC method. The cDNA of two different isoforms of the protein, Lyc e 2.01 and Lyc e 2.02, was cloned into the bacterial expressionvector pET100D. The recombinant proteinswere purified by electroelution and refolded.

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