Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: HIVBrainSeqDB: a database of annotated HIV envelope sequences from brain and other anatomical sites...
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Impairment of the CD8+ T cell response in lungs following infection with human respiratory syncytial virus is specific to the anatomical site rather than the virus, antigen, or route of infection
The most important prognostic factor is the stage at the time of presentation. Fortunately, most melanomas are diagnosed in clinical stages I and II. The revised American Joint Committee on Cancer (AJCC) staging system for melanoma is based on microscopic primary tumor depth (Breslow's thickness), presence of ulceration, evidence of nodal involvement, and presence of metastatic disease to internal sites (Table 83-3). Certain anatomic sites may affect the prognosis.
Harrison's Internal Medicine Chapter 95. Carcinoma of Unknown Primary
Carcinoma of Unknown Primary: Introduction Carcinoma of unknown primary (CUP) is a biopsy-proven (mainly epithelial) malignancy for which the anatomic site of origin remains unidentified after an intensive search. CUP is one of the 10 most frequently diagnosed cancers worldwide, accounting for approximately 3–5% of all cancer cases.
Any pigmented cutaneous lesion that has changed in size or shape or has other features suggestive of malignant melanoma is a candidate for biopsy. The recommended technique is an excisional biopsy, as that facilitates pathologic assessment of the lesion, permits accurate measurement of thickness if the lesion is melanoma, and constitutes treatment if the lesion is benign.
Carcinoma of unknown primary (CUP) is a biopsy-proven (mainly epithelial) malignancy for which the anatomic site of origin remains unidentified after an intensive search. CUP is one of the 10 most frequently diagnosed cancers worldwide, accounting for approximately 3–5% of all cancer cases. Most investigators do not consider lymphomas, metastatic melanomas, and metastatic sarcomas that present without a known primary tumor to be CUP because these cancers have specific stage- and histology-based treatments that can guide management. ...
Pathophysiology of Dysphagia
Based on anatomic site of involvement, dysphagia may be divided into oral, pharyngeal, and esophageal dysphagia. Normal transport of an ingested bolus through the swallowing passage depends on the size of the ingested bolus and size of the lumen, the force of peristaltic contraction, and deglutitive inhibition, including normal relaxation of UES and LES during swallowing.
The neurophysiology of cancer pain is complex: it involves inflammatory, neuropathic, ischaemic and
compression mechanisms at multiple sites. A knowledge of these mechanisms and the ability to decide
whether a pain is nociceptive, neuropathic, visceral or a combination of all three will lead to best practice
in pain management.
People with cancer can report the presence of several different anatomical sites of pain, which may be
caused by the cancer, by treatment of cancer, by general debility or by concurrent disorders.
It is a natural, nor can it be deemed an illaudable curiosity to be desirous of being informed of whatever
relates to those who have eminently distinguished themselves for sagacity, parts, learning, or what else may
have exalted their characters, and thereby entitled them to a degree of respect superior to the rest of their
Application to Patients
Radiation therapy can be used alone or together with chemotherapy to produce cure of localized tumors and control of the primary site of disease in tumors that have disseminated. Therapy is planned based on the use of a simulator with the treatment field or fields designed to accommodate an individual patient's anatomic features. Individualized treatment planning employs lead shielding tailored to shape the field and limit the radiation exposure of normal tissue. Often the radiation is delivered from two or three different positions.
Coagulation Disorders Associated with Liver Failure The liver is central to hemostasis because it is the site of synthesis and clearance of most procoagulant and natural anticoagulant proteins and of essential components of the fibrinolytic system. Liver failure is associated with a high risk of bleeding due to deficient synthesis of procoagulant factors and enhanced fibrinolysis. Thrombocytopenia is common in patients with liver disease and may be due to congestive splenomegaly (hypersplenism), or immune-mediated shortened platelet life span (primary biliary cirrhosis).
Kwon et al. Journal of Orthopaedic Surgery and Research 2010, 5:4 http://www.josr-online.com/content/5/1/4
Lateral femoral traction pin entry: risk to the femoral artery and other medial neurovascular structures
John Y Kwon1*, Catherine E Johnson1, Paul Appleton2, Edward K Rodriguez2
Background: Femoral skeletal traction assists in the reduction and transient stabilization of pelvic, acetabular, hip, and femoral fractures when splinting is ineffective.
Fornaro et al. Journal of Orthopaedic Surgery and Research 2010, 5:50 http://www.josr-online.com/content/5/1/50
An interactive surgical planning tool for acetabular fractures: initial results
Jürgen Fornaro1, Marius Keel2, Matthias Harders3, Borut Marincek1, Gábor Székely3, Thomas Frauenfelder1*
Background: Acetabular fractures still are among the most challenging fractures to treat because of complex anatomy, involved surgical access to fracture sites and the relatively low incidence of these lesions.