Adverse Drug Effects
premature breakdown of red blood cells (hemolysis) in subjects with a glucose6-phosphate dehydrogenase deficiency. The discipline of pharmacogenetics deals with the importance of the genotype for reactions to drugs. The above forms of hypersensitivity must be distinguished from allergies involving the immune system (p. 72). Lack of selectivity (C). Despite appropriate dosing and normal sensitivity, undesired effects can occur because the drug does not specifically act on the targeted (diseased) tissue or organ.
In many respects man’s reaction to his environment - that is his behaviour, is principally
a function of his central nervous system. Over the last few decades there have
been considerable advances in the understanding of the organisation and functions
of this system, but much remains to be discovered concerning its basic biochemistry
This growing industry also has impacts beyond revenue losses to industry and
national governments. For example, the links between intellectual property theft,
organised crime (NCIS, 2005; Union des Fabricants, 2004; OCTF, 2006) and
terrorism (Noble, 2003; Ranger and Wiencek, 2002) are increasingly well-established.
Counterfeiting offers criminals a lucrative market with a relatively low risk of
detection and minimal penalties for those convicted.
If you take a drug that makes you feel a little woozy, you should auto-
matically adjust or limit your driving to stay safe. Problems can result
when physiological changes of aging combine with drugs commonly
prescribed for older adults.
Those prescription drugs are the ones most likely to increase the risk
of driving problems and accidents. Don’t ignore your body’s reactions
when you’re on any medicines. If you feel drowsy, dizzy, nauseous, or
headachy, you should not try to drive. ...
Abbreviations: LSD, lysergic acid diethylamide; GHB, γ-hydroxybutyrate; PCP, phencyclidine; CNS, central nervous systemPrescribed, over-the-counter, and herbal medications are common precipitants of delirium. Drugs with anticholinergic properties, narcotics, and benzodiazepines are especially frequent offenders, but nearly any compound can lead to cognitive dysfunction in a predisposed patient.