Antiphospholipid antibodies

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  • Immunity seems to be a fascinating system in the human body, whose role has never been understood in detail, despite the great progress in our knowledge about its role, regulation and its disorders. The same goes for autoimmunity diseases as well as antiphospholipid antibodies presence and antiphospholipid syndrome. Due to humoral nature of these autoantibodies they can impact every tissue and due to their heterogeneity and complex actions they can be connected with wide spectrum of clinical manifestations.

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  • When searching the history of antiphospholipid antibodies one must meet cornerstone in Graham Hughes’s descriptions of antiphospholipid syndrome in his “Prosser-White Oration” to the British Society of Dermatology in 1983 (Hughes GRV; 1984). The main points of his lecture can be found in different publications (Hughes GRV; 1984, Hughes GRV; 1999, Khamastha MA; 2000) and they are still truthful although they have been expressed almost thirty years ago.

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  • The next important milestone emerged in 1990 when three independent working groups described the role of2-glycoprotein I as a target antigen in antiphospholipid antibodies’ action (Galli M, et al; 1990, Matsura E, et al; 1990, McNeil HP, et al; 1990). This discovery substantially changed point of view of many of the researchers and also clinical practisers in the topic and it led to research of 2-glycoprotein I structure, function and confirmation of significance of its antibodies presence during the next years....

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Antiphospholipid antibody profiles in lupus nephritis with glomerular microthrombosis: a prospective study of 124 cases...

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Intravenous immunoglobulin treatment of four patients with juvenile polyarticular arthritis associated with persistent parvovirus B19 infection and antiphospholipid antibodies...

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  • subject with the aim to help patients with antiphospholipid antibodies presence. Finally, this is why this book is presented to a wide range of readers. Forty seven contributors from nine countries bring together their knowledge and also their own experience from different fields of their professional work with the aim of providing a valuable resource for improving some of the points of view, decisions and treatment success in the antiphospholipid antibodies positive patients’ management.

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  • Research objectives: To analyse of obstetric history and characteristics of anticardiolipin antibody and lupus anticoagulant in pregnant women with a history of RPL; assess the effectiveness of treatment pregnancy in women with a history of RPL by antiphospholipid syndrome by coordinating regimen low doses of aspirin and low molecular weight heparin.

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  • Figure 111-1 Models of thrombosis risk. In each panel, the figure shows the thrombosis (black) potential of each risk factor present during an individual's life and the resultant thrombosis potential (red). (From FR Rosendaal: Venous thrombosis: A multicausal disease. Lancet 353:1167, 1999; with permission.) Several acquired risk factors are very strong, causing thrombosis in several percent of those afflicted, which implies a relative risk of ≥50.

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  • Models of thrombosis risk. In each panel, the figure shows the thrombosis (black) potential of each risk factor present during an individual's life and the resultant thrombosis potential (red). (From FR Rosendaal: Venous thrombosis: A multicausal disease. Lancet 353:1167, 1999; with permission.) Several acquired risk factors are very strong, causing thrombosis in several percent of those afflicted, which implies a relative risk of ≥50.

    pdf5p thanhongan 07-12-2010 24 3   Download

  • They were promised a miracle cure for the deadly diseases destroying their lives. It seemed too good to be true, but to the desperate and dying it was the only chance for survival. Now they're part of a bizarre secret experiment that reverses the aging process--an experiment gone out of control. To stop the madness, one woman must enter a shocking nightmare world, where scientists control your body--and your mind--and living makes you beg for death

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  • (BQ) Part 1 book "Harrison's rheumatology" presents the following contents: The immune system in health and disease, disorders of immune mediated - Injury. Invite you to consult.

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