Applied scientist

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  • In the modern pharmaceutical industry, high-performance liquid chromatography (HPLC) is the major and integral analytical tool applied in all stages of drug discovery, development, and production. The development of new chemical entities (NCEs) is comprised of two major activities: drug discovery and drug development. The goal of the drug discovery program is to investigate a plethora of compounds employing fast screening approaches, leading to generation of lead compounds and then narrowing the selection through targeted synthesis and selective screening (lead optimization).

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  • The primary focus of this chapter in on general approaches and considerations toward development of high-performance liquid chromatography (HPLC) methods for separation of pharmaceutical compounds, which may be applied within the various functions in the drug development continuum. It is very important to understand the aim of analysis and the requirements for a particular method to be developed. The aim of analysis of each HPLC method may vary for each developmental area in the drug development process and specific examples are given in Section 8.2.

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  • This fully revised second edition provides an exciting interdisciplinary journey through the rapidly changing landscape of discovery in microbial biotechnology. An ideal text for courses in applied microbiology and biotechnology courses, this book will also serve as an invaluable overview of recent advances in this field for professional life scientists and for the diverse community of other professionals with interests in biotechnology.

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  • After a review of the literature, the author has concluded that the concept of heat transfer was first introduced by the English scientist Sir Isaac Newton in his 1701 paper entitled “Scala Graduum Caloris.”(1) The specific ideas of heat convection and Newton’s Law of Cooling were developed from that paper

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  • The book "Applied Fracture Mechanics" presents a collection of articles on application of fracture mechanics methods to materials science, medicine, and engineering. In thirteen chapters, a wide range of topics is discussed, including strength of biological tissues, safety of nuclear reactor components, fatigue effects in pipelines, environmental effects on fracture among others. In addition, the book presents mathematical and computational methods underlying the fracture mechanics applications, and also developments in statistical modeling of fatigue.

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  • his book is served as a reference text to meet the needs of advanced scientists and research engineers who seek for their own computational fluid dynamics (CFD) skills to solve a variety of fluid flow problems. Key Features: - Flow Modeling in Sedimentation Tank, - Greenhouse Environment, - Hypersonic Aerodynamics, - Cooling Systems Design, - Photochemical Reaction Engineering, - Atmospheric Reentry Problem, - Fluid-Structure Interaction (FSI), - Atomization, - Hydraulic Component Design, - Air Conditioning System, - Industrial Applications of CFD...

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  • The first panel of our program will focus on the next generation of scientists, “Science for All Students.” We have three panelists participating in this discussion: Drs. Leon Lederman, Richard Tapia, and Marcia Linn. Dr. Lederman is an internationally renowned high-energy physicist, the Director Emeritus of Fermi National Accelerator Laboratory in Batavia, Illinois. He holds an appointment as the Pritzker Professor of Science at Illinois Institute of Technology in Chicago. Dr.

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  • It has been said that "Nothing Succeeds Like Success." What is Success? If we consult the dictionaries, they will give us the etymology of this much used word, and in general terms the meaning will be "the accomplishment of a purpose." But as the objects in nearly every life differ, so success cannot mean the same thing to all men. The artist's idea of success is very different from that of the business man, and the scientist differs from both, as does the statesman from all three. We read of successful gamblers, burglars or freebooters, but no true success was ever won or ever can be...

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  • This publication deals with mathematical modelling, dynamical process characteristics and properties. The intended audience of this book includes graduate students but can be of interest of practising engineers or applied scientists that are interested in modelling, identification, and process control. s Prepared under the project TEMPUS, S JEP-11366-96, FLACE – STU Bratislava, TU Koˇice, ˇ ˇ UMB Bansk´ Bystrica, ZU Zilina

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  • Today there is not a single aspect of the world that can escape the scrutiny of environmental analysis, and business activities stand at the crux of many issues. Some of the issues that today’s executives need to understand to be environmentally literate include: air, water, and land pollution; the production and disposal of hazardous wastes; solid waste disposal; chemical and nuclear spills and accidents; global warming and the greenhouse effect; ozone depletion; deforestation and desertification; biodiversity, and overpopulation.

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  • Since the discovery of carbon nanotubes about a decade and a half ago by Sumio Iijima, the scientific community involved in various aspects of research related to carbon nanotubes and related technologies has observed a steady progress of the science, as is typical for any new and novel material.

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  • “Dunsel … is a term used by midshipmen at Starfleet Academy. It refers to a part which serves no useful purpose.” Mr Spock, in Star Trek, Episode 53: “The Ultimate Computer” Paranoia began morphing into depression with the arrival of the 15 January 2004 issue of Nature. On page 247 was a paper by King et al. entitled ‘Functional genomic hypothesis generation and experimentation by a robot scientist’. The paper describes an automated system that uses techniques from artificial intelligence to formulate hypotheses to explain observations.

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  • The field of molecular biophysics is introduced in the following pages. The presentation focuses on the simple underlying concepts and demonstrates them using a series of up to date applications. It is hoped that the approach will appeal to physical scientists who are confronted with biological questions for the first time as they become involved in the current biotechnological revolution. The field of biochemistry is vast and it is not the aim of this textbook to encompass the whole area.

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  • .Mathematics and Religion .Templeton Science and Religion Series In our fast-paced and high-tech era, when visual information seems so dominant, the need for short and compelling books has increased. This conciseness and convenience is the goal of the Templeton Science and Religion Series. We have commissioned scientists in a range of fields to distill their experience and knowledge into a brief tour of their specialties. They are writing for a general audience, readers with interests in the sciences or the humanities, which includes religion and theology.

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  • The first edition of this text was written in the early 1990s. Since then, the field of clinical research methods has continued to develop rapidly, and this second edition has been extensively updated to reflect these developments. We have also tried to make the whole book more user friendly, both in layout and in content. All chapters now have summaries and boxes highlighting the key points, and we have provided many more illustrative examples. The biggest area of change is in our treatment of qualitative methods.

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  • Topics in Applied Physics is a well-established series of review books, each of which presents a comprehensive survey of a selected topic within the broad area of applied physics. Edited and written by leading research scientists in the f ield concerned, each volume contains review contributions covering the various aspects of the topic. Together these provide an overview of the state of the art in the respective f ield, extending from an introduction to the subject right up to the frontiers of contemporary research....

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  • In 1999, when we started teaching this course at the Department of Physics in Oslo, Computational Physics and Computational Science in general were still perceived by the majority of physicists and scientists as topics dealing with just mere tools and number crunching, and not as subjects of their own. The computational background of most students enlisting for the course on computational physics could span from dedicated hackers and computer freaks to people who basically had never used a PC.

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  • Leading experts review the research on resilience and represent the diverse perspectives and opinions found among both scientists and practitioners in the field. Although the chapters are written to the standards expected by researchers, they are equally useful for program developers and others in applied fields seeking science-based information on the topic. This book is a unique resource in keeping with the growing interest in resilience both in research and interventions.

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  • Basic elements of program Input – Initialize, define or assign numerical values to variables. Set of command expressions – Operations applied to input variables that lead to the desired result. Output – Display (graphically or numerically) result.An example of technical computinAn example of technical computing Let us consider using the hyperbolic tangent to model a downhill section of a snowboard or snow ski facility. Let us first examine the hyperbolic tangent function by executing the command: ezplot( ‘tanh(x)’ )...

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  • Cancer Epidemiology aims to train future epidemiologists to investigate the causes of cancer, including host and environmental factors in human populations. The strategies for cancer prevention and control in the general population and within disproportionately affected population include providing a better understanding of cancerrelated behaviors, identifying new markers for the early detection of cancer, providing a better understanding of cancer-related health disparities and identifying and addressing barriers to care.

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