Autoimmune disorders

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  • Sick! Diseases and Disorders, Injuries and Infections presents the latest information on 140 wide-ranging illnesses, disorders, and injuries. Included are entries on familiar medical problems readers might encounter in daily life, such as acne, asthma, chickenpox, cancer, and learning disorders. Some rare and fascinating illnesses are covered as well, such as smallpox, hantaviruses, and Creutzfeld Jakob disease (also known as mad cow disease). Entries are arranged alphabetically across the four-volume set and generally range from three to eight pages in length.

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  • Tham khảo sách 'sick! diseases and disorders, injuries and infections_2', y tế - sức khoẻ, y học thường thức phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

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  • While history and examination will always remain the foundation of neurolog- ical diagnosis, MRI and CT have now become the most important diagnostic tests used by neurologists and neurosurgeons. These tests are critical not only for confirming clinical diagnosis, but in many cases will give additional infor- mation absolutely essential to patient care. Modern clinical diagnosis and treat- ment of central nervous system disorders relies heavily upon neuroimaging. In some cases, the optimal management of clinical problems affecting patients with brain tumors, strokes, etc.

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  • Episcleritis This is an inflammation of the episclera, a thin layer of connective tissue between the conjunctiva and sclera. Episcleritis resembles conjunctivitis but is a more localized process and discharge is absent. Most cases of episcleritis are idiopathic, but some occur in the setting of an autoimmune disease. Scleritis refers to a deeper, more severe inflammatory process, frequently associated with a connective tissue disease such as rheumatoid arthritis, lupus erythematosus, polyarteritis nodosa, Wegener's granulomatosis, or relapsing polychondritis.

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  • As an endocrinologist, I am very familiar with the importance of the endocrine glands to human functioning. These glands work continuously to maintain the health of all individuals as we move through each and every day of our lives. In fact, when one or more of the endocrine glands malfunction, the person’s entire system is often thrown into disarray. For example, if a person develops Hashimoto’s thyroiditis, an autoimmune disorder that causes hypothyroidism, the person’s once-normal thyroid levels will drop. He or she may become lethargic and show a variety of symptoms.

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  • Researchers have theorized that anti-inflammatory medications may help prevent diseases, such as coronary artery diseases (CAD), cardio vascular diseases (CVD), stroke, colon cancer and Alzheimer’s. Several recent findings from different laboratories in the world employing case-control human studies and/or specific animal models for chronic human diseases support these ideas.

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  • Therapeutic immunosuppression has very broad applications in clinical medicine, ranging from prevention and treatment of organ and bone marrow transplant rejection, management of various autoimmune disorders (e.g., rheumatoid arthritis), skin diseases, allergies and asthma. Whereas traditionally only a small repertoire of immunosuppressive agents was available for clinical use, recent discoveries have significantly increased the number of approved agents, resulting in numerous trials to further evaluate their potential.

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  • Cancer is one of the leading causes of deaths in the industrialized world (World Health Organization [WHO], 2004) and the second leading cause of death in Germany (Federal Statistical Office of Germany [DeStatis], 2007). It has been demonstrated that migrant cancer incidence and mortality differs in general from cancer patterns in the respective host population. Cancer is known to have a long latency period between exposure and disease onset. Important exposure factors can be traced back to childhood and young adulthood.

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  • Celiac disease has many names, such as gluten intolerance, gluten-sensitive enteropathy, and non-tropical sprue. Each name depicts a life-long autoimmune disorder in which a person’s body cannot tolerate a group of grain proteins known as gluten. These grains consist of wheat, rye, barley, and any derivatives of these grains. Oats were always part if this list, but recent studies have shown that a moderate consumption of oats is safe for healthy children and adults who are well-established on a gluten-free diet....

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  • The ears therefore pertain to the kidney and kidney also control anterior and posterior orifices. Anterior orifice" refers to the urethra and genitalia which have the function of urination and reproduction. "Posterior orifice" refers to the anus which has the function of excreting the feces. Decline or deficiency of kidney Qi, therefore, may give rise to frequency of micturition, enuresis, oliguria and anuria, seminal emission, impotence, premature ejaculation and infertility in reproduction, and prolonged diarrhea with prolapse of rectum or constipation....

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  • The past several decades have seen dramatic advances in understanding the etiopathogenesis of glomerulonephritis. The science of renal disease has progressed steadily from a discipline focused largely on whole organ physiology, through successive eras of cell and molecular biology, several omics (proteomics, genomics) and now into molecular mapping and personalized medicine.

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity...

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  • Human parvovirus B19 (B19) is known to induce apoptosis that has been associated with a variety of autoimmune disorders. Although we have previously reported that B19 non-structural protein (NS1) induces mitochondrial-dependent apoptosis in COS-7 cells, the precise mechanism of B19-NS1 in developing autoimmunity is still obscure.

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  • Apoptosis or programmed cell death is an inherent part of the development and homeostasis of multicellular organisms. Dysregulation of apoptosis is implicated in the pathogenesis of diseases such as cancer, neurodegenera-tive diseases and autoimmune disorders. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is able to induce apoptosis by binding death receptor (DR)4 (TRAIL-R1) and DR5 (TRAIL-R2), which makes TRAIL an interesting and promising therapeutic target.

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  • According to the Centers for Disease Control and Prevention, 13 percent of women aged eighteen years and older are in poor, or merely fair, health. More than 12 percent of women face a limitation in their usual activities due to chronic health conditions. In addition, 62 percent of women aged twenty years and older are overweight, a key predictor of future health problems. Moreover, the medical concerns women face often differ from those of most concern to men.

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  • Harrison's Internal Medicine Chapter 64. The Practice of Genetics in Clinical Medicine Implications of Molecular Genetics for Internal Medicine The field of medical genetics has traditionally focused on chromosomal abnormalities (Chap. 63) and Mendelian disorders (Chap. 62). However, there is genetic susceptibility to many common adult-onset diseases, including atherosclerosis, cardiac disorders, asthma, hypertension, autoimmune diseases, diabetes mellitus, macular degeneration, Alzheimer's disease, psychiatric disorders, and many forms of cancer.

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  • Celiac Disease (CD) or Gluten Sensitive Enteropathy (GSE) is a life‐long disorder. It is characterized by inflammation in the small intestine of genetically predisposed individuals caused by inappropriate immune response to gluten, a protein enriched in some of our common grains (wheat, rye and barley). The toxicity of gluten is manifested by the autoimmune action of T‐lymphocytes on mucosal cells in the small intestine, disrupting its vital function of absorbing nutrients from food.

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  • Immunity seems to be a fascinating system in the human body, whose role has never been understood in detail, despite the great progress in our knowledge about its role, regulation and its disorders. The same goes for autoimmunity diseases as well as antiphospholipid antibodies presence and antiphospholipid syndrome. Due to humoral nature of these autoantibodies they can impact every tissue and due to their heterogeneity and complex actions they can be connected with wide spectrum of clinical manifestations.

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  • Among the swallowing disorders, dysphagia is the most prevalent and dangerous due to the fact it can lead to tumor formation. The classification of swallowing disorders into obstructive and non-obstructive including e.g. lower motor neuron dysfunction, autoimmune disease and achalasia were discussed in this chapter. The authors also referred to motility disorders in diabetic neuropathy, alcoholism, psychiatric illness and scleroderma – an autoimmune disease that causes weakening of the tissues of the esophagus....

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  • Palpable purpura are further subdivided into vasculitic and embolic. In the group of vasculitic disorders, cutaneous small-vessel vasculitis, also known as leukocytoclastic vasculitis (LCV), is the one most commonly associated with palpable purpura (Chap. 319). Underlying etiologies include drugs (e.g., antibiotics), infections (e.g., hepatitis C virus), and autoimmune connective tissue diseases. Henoch-Schönlein purpura is a subtype of acute LCV that is seen primarily in children and adolescents following an upper respiratory infection.

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