Xem 1-20 trên 49 kết quả Bacterial complex
  • Abstract Complex I is the fi rst enzyme of the respiratory chain and plays a central role in cellular energy production. It has been implicated in many human neurodegenerative diseases, as well as in ageing. One of the biggest membrane protein complexes, varying in size from 0.5 to 1 MDa, it is an L-shaped assembly consisting of hydrophilic and membrane domains. Previously, we determined the structure of the hydrophilic domain in several redox states. It established the pathway for electron transfer from NADH to quinone via seven Fe-S clusters.

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  • The complex world of polysaccharides is a compilation of the characteristics of a variety of polysaccharides from plants, animals and microorganisms. The diversity of these polysaccharides arises from the structural variations and the monosaccharide content which is under genetic control. The chemical and physical properties have made them useful in many pharmaceutical, food and industrial applications.

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  • Nowadays, with over a thousand bacterial genomes sequenced, even greater opportunities have opened for experimental or computational global analysis of metabolism, physiology, and evolution. In particular, the access to comprehensive sets of molecular components (genes, proteins, regulatory signals) is at the basis of the development of novel integrative approaches, aiming at understanding the function of specific sets of these components (operons, regulons, metabolic pathways, protein complexes, etc.) in the context of the whole organism.

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  • More recent studies using molecular methods and a retrievable enamel chip model have revealed a new line-up of initial colonizers though the early dental plaque microflora varies at subject-specific basis (Diaz et al., 2006; Kolenbrander et al., 2005). In initial plaque on the chip at four to eight hours, Streptococcus spp. was dominant while Veillonella, Gemella, Prevotella, Niesseria, Actinomyces and Rothia were also frequently found. Among streptococci, S. oralis, S. mitis, S. infantis, S. sanguinis, S. parasanguinis, S. gordonii, S. cristatus and S.

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  • The Environmental, Health, and Safety (EHS) Guidelines are technical reference documents with general and industry- specific examples of Good International Industry Practice (GIIP) 1. When one or more members of the World Bank Group are involved in a project, these EHS Guidelines are applied as required by their respective policies and standards. These industry sector EHS guidelines are designed to be used together with the General EHS Guidelines document, which provides guidance to users on common EHS issues potentially applicable to all industry sectors.

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  • During high precipitation, infiltration of sulphates and chromates occurred, and subsequently when low precipitation, the aquifer without recharge becomes a confined environment favourable to a reduction of sulphates to sulphide (H2S and HS¯) by a complex biochemical process (a phenomenon called sulphatoreducing), due to the bacterial activity. Subsequently, this reduction results from the sulphur rejected (Khe´rici et al., 2009) by a sulphato-reducing bacteria (Desulfovibrio desulfricans), which can transform of Cr(VI) to Cr(III) which is a stable substance.

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  • The pathogenesis of osteomyelitis is a complex process involving interactions between a host and an infectious agent. The host’s inflammatory response to a pathogen can further the physical spread of disease by clearing space in bone. Predisposing genetic differences in immune function are increasingly seen as an aetiological factor in some cases of osteomyelitis. Acquired factors such as diseases causing immune or vascular compromise and implantation of foreign materials are frequently involved in the disease process as well. ...

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  • Take molecular genetics and bioinformatics for example; these are perhaps two of the most exciting areas of biology and are beginning to have an impact on other areas of medical therapeutics such as cancer and diabetes, and provide a signpost to ‘personalised medicine’. Yet recent genome wide association (GWAS) studies of large samples, have demonstrated that in schizophrenia around 1000 or more genetic variants of low penetrance may be implicated in the heritability of schizophrenia.

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  • Sepsis has been defined as a serious condition in which there is a systemic inflammation secondary to an infectious process. This can progress to a level at which it results in a complex disorder, leading to multiple organ failure and eventually death. Although it has been well recognized as one of the top killers worldwide, its incidence continues to rise dramatically with some studies showing approximately 1,400 daily deaths. Some experts usually consider sepsis as one of the most challenging conditions because of its multiple presentations and the variety of its complications. ...

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  • Mathematical modelling is the process of formulating an abstract model in terms of mathematical language to describe the complex behaviour of a real system. Mathematical models are quantitative models and often expressed in terms of ordinary differential equations and partial differential equations. Mathematical models can also be statistical models, fuzzy logic models and empirical relationships. In fact, any model description using mathematical language can be called a mathematical model.

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  • Destinations are some of the most difficult entities to manage and market, due to the complexity of the relationships of local stakeholders (Sautter and Leisen,1999). Managing and marketing destinations is also challenging because of the variety of stakeholders involved in the development and production of tourism products. The destination experience is essentially comprised of regions, resources and amalgams of tourism facilities and services, which often do not belong to individuals.

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  • In the European Union, the existing insurance and reinsurance directives do not contain any provisions that place reliance on credit rating agencies. There is no explicit credit risk charge for the solvency margin in the Solvency I framework. The solvency margin in the Solvency I framework is not the sum of different capital charges related to different risks, but a single capital charge calibrated to reflect all the risks an insurance company faces.

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  • An imposing barrier to entry for current plant-derived materials, and the issue most often debated, is the competitive cost situation. In many cases, the current cost of using plant-based materials is viewed as being relatively high, and not competitive with hydrocarbon-based processes. However, the cost-competitive situation contains several highly complex interactions among the key factors: value of product, cost of materials, volume of throughput, degree of processing required, and performance of the building blocks used.

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  • The auditor must be independent of the issuer and — in the case of mutual funds, independent of the investment company complex. Audit committees should be familiar with the statutory and regulatory independence requirements for auditors, including requirements that the auditor advise the audit committee of any services or relationships that reasonably can be thought to bear on the firm’s independence. The technical competence of the auditor alone is not sufficient to ensure a high-quality audit. The auditor also must exercise a high level of objectivity and professional skepticism.

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  • Oligomerization into multimeric complexes is a prerequisite for the chaperone function of almost all a-crystallin type heat shock proteins (a-Hsp), but the molecular details of complex assembly are poorly understood. The a-Hsp proteins from Bradyrhizobium japonicum are suitable bacterial models for structure-function studies of these ubiquitous stress proteins. They fall into two distinct classes, A and B, display chaperone activity in vitro and form oligomers of  24 subunits.

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  • In the present study intestinal delivery systems resistant to gastric juice, loaded with the probiotic bacteria Lactobacillus acidophilus LA14 and Bifidobacterium lactis BI07, were produced by the polyelectrolyte complexation. First, beads were prepared by the traditional extrusion method and nine formulations were developed using alginate as main carrier and the biopolymer, xanthan gum, as hydrophilic retardant polymer or the cellulose derivative, cellulose acetate phthalateDevelopment of microparticulate systems for intestinal delivery of Lactobacillus acidophilus and Bifidobacterium lactis.

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: CD14 mediates the innate immune responses to arthritopathogenic peptidoglycan–polysaccharide complexes of Gram-positive bacterial cell walls...

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  • The goal of the Child Health program is “to enable all children to attain and sustain optimal health and develop- mental potential.” (1) Achievement of this goal involves a complex interplay of internal and external factors for families and their children. Accordingly, the Child Health Program Standard is structured around six key areas: positive parenting; breastfeeding; healthy family dynamics; healthy eating, healthy weights and physical activity; growth and development; and oral health.

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  • Cells have evolved complex and overlapping mechanisms to protect their proteins from aggregation. However, several reasons can cause the failure of such defences, among them mutations, stress conditions and high rates of protein synthesis, all common consequences of heterologous protein pro-duction.

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  • Microscopic and light spectroscopic investigations on the supramolecular architecture of bacterial photosynthetic membranes have revealed the pho-tosynthetic protein complexes to be arranged in a densely packed energy-transducing network.

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