Basic genetics

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  • Readable, well organized, and easy to use, this outstanding encyclopedia signifies a timely and major advance in providing in-depth and comprehensive coverage of medical genetics for the lay reader. The two volumes include nearly 400 substantive entries on genetic diseases and conditions as well as information on basic genetics concepts such as DNA, chromosomes, genetic testing, and pedigree analysis and construction (genetic family history).

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  • Learners enrolled in all healthcare training programs need to have a basic understanding of medical genetics so that they can successfully transition from students to clinicians. The field of medical genetics is advancing at a fast pace and is becoming increasingly integral to all aspects of medicine. This fact emphasizes the need for every practicing clinician and faculty member to develop an in-depth knowledge of the principles of human genetics, given that they are applicable to such a wide variety of clinical presentations.

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  • For otolaryngology–head and neck surgeons in training as residents and fellows, it is a difficult task to keep up with all of the advances in the basic and clinical sciences that impact the medical and surgical practice of their specialty. It is also pertinent to the practice of otolaryngology–head and neck surgery for interested medical students and lecturers in medical school faculties who teach students and resident physicians to have a reference book that clearly presents the basic principles.

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  • When we agreed to edit this book for a second edition, we looked forward to a bit of updating and including some of our latest research results. However, the effort grew rapidly beyond our original vision. The use of genetic algorithms (GAs) is a quickly evolving field of research, and there is much new to recommend. Practitioners are constantly dreaming up new ways to improve and use GAs. Therefore this book differs greatly from the first edition.

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  • Polymerase Chain Reaction is widely held as one of the most important inventions of the 20th century in molecular biology. Small amounts of the genetic material can now be amplified to be able to a identify, manipulate DNA, detect infectious organisms, including the viruses that cause AIDS, hepatitis, tuberculosis, detect genetic variations, including mutations, in human genes and numerous other tasks.

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  • In the last decade the progress of molecular biology has made a strong influence on the theoretical framework of population genetics and evolution. Introduction of molecular techniques in this area has resulted in many new discoveries. As a result, a new interdisciplinary science, which may be called 'Molecular Population Genetics and Evolution', has emerged. In this book I have attempted to discuss the development and outline of this science. In recent years a large number of papers have been published on this subject.

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  • We have endeavoured to make A Primer of Conservation Genetics as com- This book is intended to provide a brief accessible introduction to the general principles of conservation genetics prehensible as possible to a broad range of readers. It is suitable for those undertaking introductory genetics courses at university, for students undertaking conservation biology courses and even for motivated first-year biology students who have completed lectures on basic Mendelian genetics and introductory population genetics (allele frequencies and Hardy--Weinberg equilibrium).

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  • Experimental autoimmune encephalomyelitis can be induced in susceptible animals by immunodominant deter-minants of myelin basic protein (MBP).

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  • Chapter 2 covers the basic principles of inheritance, first described by Mendel, that form the foundation of the Laws of Segregation and Independent Assortment. You will see in chapter 4 how these laws relate to chromosome segregation during meiosis.

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  • Chapter 17 - Somatic mutation and the genetics of cancer. The genetics of cancer are clearly more complex than most of the other diseases. In this chapter, we attempt to answer some basic questions about this topic that hopefully will help put the chapters on cancer in perspective and explain their organization.

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  • The number of DNA sequences and transcription factors that regulate transcription is much greater than originally anticipated. Most genes contain at least 15–20 discrete regulatory elements within 300 bp of the transcription start site. This densely packed promoter region often contains binding sites for ubiquitous transcription factors such as CAAT box/enhancer binding protein (C/EBP), cyclic AMP response element–binding (CREB) protein, selective promoter factor 1 (Sp-1), or activator protein 1 (AP-1).

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  • Three years have passed since the first edition of Basics of Environmental Science appeared. During this time new concerns have arisen, the controversy in Britain over the safety and desirability of genetically modified foods being the most spectacular example. At the same time, our understanding of other issues has improved as more information about them has been gathered.

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  • Since the beginning of human history, people have wondered how traits are inherited from one generation to the next. Although children often look more like one parent than the other, most offspring seem to be a blend of the characteristics of both parents. Centuries of breeding of domestic plants and animals had shown that useful traits - speed in horses, strength in oxen, and larger fruits in crops - can be accentuated by controlled mating. However, there was no scientific way to predict the outcome of a cross between two particular parents. ...

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  • The diversity and specialization in orchid floral morphology have fascinated botanists and collectors for centuries. In the past 10 years, the orchid industry has been growing substantially worldwide. This interesting book focuses on the recent advances in orchid biotechnology research since the last 10 years in Taiwan. To advance the orchid industry, enhancement of basic research as well as advanced biotechnology will provide a good platform to improve the flower quality and breeding of new varieties.

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  • After leaving school in Sheffield, UK, Steve worked in the print industry for 10 years before being made redundant. He decided to return to education and completed courses in many subjects including Information Technology, Business and Finance, Sound Engineering and Music Production, Science and a BSc. in Biomedical Science. After graduating, Steve had several jobs in various scientific fields including immunology and developmental genetics, during which time he developed a keen interest in digital imaging which progressed into an interest in creative Photography.

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  • It is my privilege to contribute the foreword for this unique volume entitled: “Plant Tissue Culture Engineering,” edited by S. Dutta Gupta and Y. Ibaraki. While there have been a number of volumes published regarding the basic methods and applications of plant tissue and cell culture technologies, and even considerable attention provided to bioreactor design, relatively little attention has been afforded to the engineering principles that have emerged as critical contributions to the commercial applications of plant biotechnologies.

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  • Now fully updated to reflect recent advances, this introduction provides a broad, but concise, coverage of recombinant DNA techniques. Written for advanced undergraduates, graduates and scientists who want to use this technology, emphasis is placed on the concepts underlying particular types of cloning vectors to aid understanding and to enable readers to devise suitable strategies for novel experimental situations. An introduction to the basic biochemical principles is presented first. Then PCR and cloning using E.

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  • The growing interest in the application of artificial intelligence (AI) techniques to power system engineering has introduced the potentials of using this state-of-the-art technology. AI techniques, unlike strict mathematical methods, have the apparent ability to adapt to nonlinearities and discontinuities commonly found in power systems. The best-known algorithms in this class include evolution programming, genetic algorithms, simulated annealing, tabu search, and neural networks. In the last three decades many papers on these applications have been published.

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  • During the last three decades, important advances have been made in the available treatments for the loss of skeletal tissue as a result of trauma or disease. The application of large skeletal allografts and total joint replacement have become successful and reproducible treatment options. Unfortunately there still is a significant incidence of failure because of mechanical or biological complications.

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  • Inflammatory bowel disease research is changing. Progress in defining and treating these diseases is advancing in lock step with the furious pace of technological advances that continue to refine the tools of discovery. With sequencing of the entire genome completed, genetics research is providing direction for molecular and immunological in vivo and in vitro investigation, which in turn directs the development of targeted therapeutics.

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