Plants defend themselves from other organisms by elaborating bioactive chemical
defences. This is the essential basis of the use of herbal medicines that still represents a
major therapeutic resort for much of humanity However, at the outset, it must be stated that
any plant that is not part of our evolved dietary cultures is potentially dangerous.
Commercial herbal medicinal preparations approved by expert regulatory authorities have a
significant place in mainstream conventional medicine and in complementary medicine.
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian)...
The health-promoting effects attributed to olive oil, and the development of the olive oil industry have intensified the quest for new information, stimulating wide areas of research. This book is a source of recently accumulated information. It covers a broad range of topics from chemistry, technology, and quality assessment, to bioavailability and function of important molecules, recovery of bioactive compounds, preparation of olive oil-based functional products, and identification of novel pharmacological targets for the prevention and treatment of certain diseases....
Life on Earth is dependent on sunlight. In the process known as photosynthesis, plants,
algae and certain bacterias are capable of using this source of energy to drive the synthesis
of organic compounds. The oxygenic photosynthesis results in the release of molecular
oxygen and the removal of carbon dioxide from the atmosphere that is used to synthesize
In recent years there has been a renewed interest in
solid-state fermentation (SSF) processes for the production
of bioactive compounds. While efforts continue
largely to exploit filamentous fungi and yeasts for the
production of various enzymes, attempts have also been
made to explore possibilities of using bacterial strains in
SSF systems (Pandey et al., 2000). Enzyme production
by SSF using bacterial spp.
Cyclooxygenases (COXs) catalyze the rate-limiting step in the production of prostaglandins, bioactive compounds involved in processes such as fever and sensitivity to pain, and are the target of aspirin-like drugs. COX genes have been cloned from coral, tunicates and vertebrates, and in all the phyla where they are found, there are two genes encoding two COX isoenzymes; it is unclear whether these genes arose from an early single duplication event or from multiple independent duplications in evolution. The...
Acute leukemia is a proliferation of immature bone marrow-derived cells (blasts) that may
also involve peripheral blood or solid organs. The percentage of bone marrow blast cells
required for a diagnosis of acute leukemia has traditionally been set arbitrarily at 30% or more.
However, more recently proposed classification systems have lowered the blast cell count to
20% for many leukemia types, and do not require any minimum blast cell percentage when
certain morphologic and cytogenetic features are present....
B-Sitosterol, stigmasterol and a minor compound 5,6-dehydrokawain were isolated from the ethanol extract of the rhizomes of Alpinia globosa, a medicinal plant of Vietnam. The paper provides characteristic spectra and HPLC profile of the natural -pyrone 5,6- dehydrokawain that would be useful for the purpose of fast determination of this bioactive compound in plant extracts.
Calibration is the most important step in bioactive compound analysis. A good Precision
and accuracy can only be obtained when a good calibration procedure is adopted. In the
Spectrophotometric methods, the concentration of a sample cannot be measured directly,
but is determined using physical measuring quantity ‘y’ (absorbance of a solution). An
unambiguous empirical or theoretical relationship can be shown between this quanity and
the concentration of an analyte.
A rye kernel contains large amounts of important dietary ﬁ bre
components combined with other bioactive compounds, which
have numerous positive functions for our health and well-being.
Rye contains both soluble and insoluble dietary ﬁ bre. The main
dietary ﬁ bre component in rye is the partly soluble arabinoxylan.
In bread making, the cell wall polysaccharides in rye have a
profound effect on the rheological properties of dough and bread.
The macronutrients in rye are the same as in other cereals: starch,
dietary ﬁ bre, and protein.
Pesticides are divided to insecticides, fungicides, herbicides, rodenticides, acaricides
and nematocides according to the organisms that they affect. There are various forms
of insecticides; most are repellants or insect growth regulators used in agriculture,
public health, horticulture or food storage. It is evident that insecticides have been
used to boost food production to a considerable extent and to control disease vectors.
In food matrices, bioactivity of polyphenols like all dietary antioxidants in the human body,
depends firstly on their bioaccessibility (i.e. the release from the food matrix) and
bioavailability (i.e. absorbable fraction that can be used for specific physiological functions in
organs). Polyphenols of comparatively high bioavailability include isoflavonids (absorption
cover 50%, Bohn, 2010), while e.g. anthocyanins are of very low bioavailability, usually ca.
1.7% (Sakakibara et al., 2009). The prerequisite for bioavailability of any compound is its
bioaccessibility in the gut.
Gonadotropin-releasing hormone antagonists (GnRH-nt) available for clinical use are GnRH molecules with amino acid modiﬁcations in positions 1, 2, 3, 6, and 10. They are not associated with the histaminic-release effects of previous compounds (1). These compounds immediately block GnRH receptor in a competitive fashion (2). They decrease the luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion within a period of eight hours. Inhibition of LH secretion is more important than FSH.
A new polymer "heparinanalogy" has been synthesized from vinylsaccharide compounds. This Polymer contains O-sulfat-, N-sulfat-, carboxyl- and hydroxyl groups, degree of sulfation (DS) per basic molecule unit is 2,3. The tests of bioactivity confirm that synthesized polymer is blood compatible and antithrombin.
Lipopolysaccharide (LPS) from the outer membrane of Gram-negative bac-teria belongs to the most potent activators of the mammalian immune sys-tem. Its lipid moiety, lipid A, the ‘endotoxic principle’ of LPS, carries two
negatively charged phosphate groups and six acyl chain residues in a
defined asymmetric distribution (corresponding to synthetic compound