(BQ) Part 2 book "Color atlas of pharmacology" presentation of content: Drugs acting on the sympathetic nervous system, nervous system nervous system, cardiac drugs, biogenic amines, antipyretic analgesics, drugs for the suppression of pain, plasma volume expanders,... and other contents.
In many countries, medicine is at present
facing urgent political and economic calls
for reform. These socioeconomic pressures
notwithstanding, pharmacotherapy has always
been an integral part of the health care
system and will remain so in the future.
Well-founded knowledge of the preventive
and therapeutic value of drugs is a sine qua
non for the successful treatment of patients
entrusting themselves to a physician or
Because of the plethora of proprietary medicines
and the continuous influx of new
pharmaceuticals, the drug market is dif cult
to survey and hard to understand.
Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are rare and heterogeneous
neoplasms with overall increasing incidence, but not an associated increase in survival rate
over the past few decades. Tumors originate from at least 16 different cells of diffuse
endocrine system (DES), scattered through mucosa of gastrointestinal tract. They are mainly
sporadic, but sometimes exhibit familial inheritance.
Psychiatric disturbance is common in both folate and cobalamin deficiencies. This, like the neuropathy, has been attributed to a failure of the synthesis of SAM, which is needed in methylation of biogenic amines (e.g., dopamine) as well as of proteins, phospholipids, and neurotransmitters in the brain (Fig. 100-1). Associations between lower serum folate or cobalamin levels and higher homocysteine levels and the development of Alzheimer's disease have been reported.
The Rhodopsin family of G protein coupled receptors (GPCRs) includes
the phylogenetic a-group consisting of about 100 human members. The
a-group is the only group of GPCRs that has many receptors for biogenic
amines which are major drug targets. Several members of this group are
orphan receptors and their functions are elusive. In this study we present a
detailed phylogenetic and anatomical characterization of the Gpr153 recep-tor and also attempt to study its functional role.