The past decade has seen the field of proteomics expand from a highly technical endeavor to a widely utilized technique. The objective of this book is to highlight the ways in which proteomics is currently being employed to address issues in the biological sciences. Although there have been significant advances in techniques involving the utilization of proteomics in biology, fundamental approaches involving basic sample visualization and protein identification still represent the principle techniques used by the vast majority of researchers to solve problems in biology.
The art of compliance is a craft much like that of a carpenter who learns to
work with various kinds of wood and designs. Ours is an industry wrought
with differences. While the regulations that govern FDA-regulated industries
are proscribed, how the regulations are interpreted and applied really
depends on experience and how well one has mastered the craft of compliance.
There are no proscribed procedures, but there are guideposts common
to all FDA-regulated industries, whether a firm manufactures medical
devices, pharmaceuticals, or biological products....
This book, with its 16 chapters, documents the present state of knowledge of the
adenosine A3 receptor. It covers a wide range of information, including data from
studies of theoretical, molecular and cellular pharmacology, signal transduction,
integrative physiology, new drug discoveries and clinical applications. It fills an
important gap in the literature since no alternative source of such information is
This issue of the journal reports some selected contributions from the workshops
BioConcur 2004 chaired by Anna Ingolfsdottir and Hanne Riis Nielson and
BioConcur 2005 chaired by Bud Mishra and Corrado Priami.
There are three contributions from BioConcur 2004. The ﬁrst one is by
Calder, Gilmore and Hillston on the modelling of signalling pathways using the
stochastic process algebra PEPA. The second contribution is by Kuttler and
Niehren on gene regulation in π-calculus.
Drug abuse in the developed world is an international problem. In the USA, in an
effort to deter drug use and identify abusers so they may receive treatment, testing
an individual’s urine has become a large commercial enterprise. Drug testing has also
been a traditional part of clinical care in medicine and in the medicolegal investigation
of death. While scientists conducting drug testing in the postmortem arena routinely
analyze a variety of biological matrices, the specimen of choice in the drug testing
industry in the USA is urine and in clinical medicine, serum.
The general objectives of the study are to evaluate the status and to find out scientific basis to develop freshwater prawn culture in brackish water, in order to diversify culture systems and species, to stabilize social-economics for inhabitants, and to adapt to the issues of sea level rise and saltwater intrusion in Mekong Delta.
Agricultural biotechnology offers great promise for Africa and tissue culture and marker-assisted selection are already in widespread use across the continent. However, the safe application of these technologies requires functioning biosafety systems. The report focuses on the special issues related to biosafety in Africa.Crops can be improved by conventional breeding, by tissue culture and by marker-aided selection. But for many improvements - such as drought and salinity tolerance - GM technology is going to be essential.
Ten years ago when I wrote the foreword to the first edition of this book, the
concept of women’s health was changing at a rapid pace. The focus was just
shifting from solely reproductive issues and biological factors, to an expanded
perception that women’s health encompasses biological, familial, cultural, economic,
emotional, psychological, and behavioral elements of each woman and her
sociopolitical environment, beyond just the reproductive organs and across her
The long-awaited sequel to the "Concepts and Practice of Mathematical Finance" has now arrived. Taking up where the first volume left off, a range of topics is covered in depth. Extensive sections include portfolio credit derivatives, quasi-Monte Carlo, the calibration and implementation of the LIBOR market model, the acceleration of binomial trees, the Fourier transform in option pricing and much more. Throughout Mark Joshi brings his unique blend of theory, lucidity, practicality and experience to bear on issues relevant to the working quantitative analyst....
Wetland ecosystems are a natural resource of global significance.Historically,
their high level of plant and animal (especially bird) diversity is perhaps the
major reason why wetland protection has become a high priority worldwide,
supported by international agreements, such as the Ramsar Convention and
the International Convention of Biological Diversity (Fig. 1.1).
Global agriculture is now at the crossroads. The Green Revolution of the last century that gave many developing countries such as India a breathing spell, enabling them to adjust the growth of their human populations better to the supporting capacity of their ecosystems, is now in a state of fatigue. Average growth rates in food production as well as factor productivity in terms of yield per unit of mineral fertilizer (NPK) are both declining.
IAS 2 Inventories was issued by the International Accounting Standards Committee in
December 1993. It replaced IAS 2 Valuation and Presentation of Inventories in the Context of the
Historical Cost System (originally issued in October 1975).
The Standing Interpretations Committee developed SIC-1 Consistency—Different Cost Formulas
for Inventories, which was issued in December 1997
However, despite sharing a common signature CLLs expressing mutated and unmutated
IgVH genes differentially express more than 100 genes. Among these, over-expression of
genes encoding zeta-chain-associated protein 70 (ZAP-70), lipoprotein lipase (LPL), BCL-7a,
dystrophin and gravin are observed in the aggressive unmutated cases, while stable
mutated cases over-express Wnt3, CTLA-4, NRIP1 nuclear receptor gene, ADAM29 and the
transcription factor TCF7 . These results suggest that indolent mutated and aggressive
unmutated CLLs constitute two variants of the same disease.
This edition aims to present some relevant topics in the histopathology area that may be of interest for medical doctors and for other professionals interested in pathology. Histopathology applies basic knowledge obtained from biologic and anatomic science to make diagnosis, to determine the severity and progress of a condition and to evaluate the possible response to certain therapies. Thus, it is not surprising that this discipline constantly expands with progresses produced in biology.
This issue of Forced Migration Review is about improving communications between
logisticians and programme managers to make such mix-ups a thing of the past. We are
grateful to the Fritz Institute for drawing our attention to the importance of humanitarian
logistics and for the very generous grant which has made this issue possible. We are
deeply indebted to our Guest Editors, Anisya Thomas (Fritz Institute's Managing
Director) and Ricardo Ernst (Georgetown University), and to Lynn Fritz for his
The New Biology set consists of the following six volumes: The Cell,
Animal Cloning, Stem Cell Research, Gene Therapy, Cancer, and Aging.
The set is intended primarily for middle and high school students, but
it is also appropriate for first-year university students and the general
public. In writing this set, I have tried to balance the need for a comprehensive
presentation of the material, covering many complex fields,
against the danger of burying—and thereby losing—young students
under a mountain of detail.
The last few years have witnessed tremendous changes in the syllabi of environmentally
related courses at Advanced Level and in tertiary education. Moreover, there have been
major alterations in the way degree and diploma courses are organised in colleges and
universities. Syllabus changes reflect the increasing interest in environmental issues,
their significance in a political context and their increasing relevance in everyday life.
Rarely in the modern history of humans has biology played such an
important role in human affairs as it does today. In the eighteenth and
nineteenth centuries, explorers stimulated the first major advance in biology by
bringing back countless new species that Darwin, and others, put into a logical
order based on the theory of natural selection. The development of evolutionary
thinking and the clarification of the rules of genetic inheritance resulted in the
theoretical base for targeted artificial selection—an essential component of
progress in biology and agriculture....