Biophysical mechanisms

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  • This book presents a full spectrum of views on current approaches to modeling cell mechanics. The authors of this book come from the biophysics, bioengineering, and physical chemistry communities and each joins the discussion with a unique perspective on biological systems. Consequently, the approaches range from finite element methods commonly used in continuum mechanics to models of the cytoskeleton as a cross-linked polymer network to models of glassy materials and gels.

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  • Tham khảo sách 'environmental health criteria 238 extremely low frequency fields', y tế - sức khoẻ, y học thường thức phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

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  • The notion of Ecosystem Services (ES: (Daily 1997; Carpenter 2003; Kremen and Ostfeld 2005) provides a cohesive scientific view of the many mechanisms through which nature contributes to human well-being. Focusing on both the biophysical mechanisms of ES provision and the economic implications of ES use can allow our societies to balance the sides of the “nature vs. the economy” equation, leading to better management and governance (Millennium Ecosystem Assessment 2002).

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  • The first Environmental Health Criteria (EHC) monograph, on mercury, was published in 1976 and since that time an ever-increasing number of assessments of chemical and of physical agents have been produced. In addition, many EHC monographs have been devoted to evaluating toxicological methodology, e.g. for genetic, neurotoxic, teratogenic and nephrotoxic agents. Other publications have been concerned with epidemiological guidelines, evaluation of short-term tests for carcinogens, biomarkers, effects on the elderly and so forth....

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  • Aegyptin is a 30 kDa mosquito salivary gland protein that binds to collagen and inhibits platelet aggregation. We have studied the biophysical properties of aegyptin and its mechanism of action. Light-scattering plot showed that aegyptin has an elongated monomeric form, which explains the apparent molecular mass of 110 kDa estimated by gel-filtration chromatography.

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  • The vascular endothelium is exposed to an array of physical forces, includ-ing shear stress via blood flow, contact with other cells such as neighboring endothelial cells and leukocytes, and contact with the basement membrane. Endothelial cell morphology, protein expression, stiffness and cytoskeletal arrangement are all influenced by these mechanochemical forces.

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  • Our laboratory is interested in the biochemical and biophysical basis of cell structure. The structure of a cell is determined primarily by its cytoskeleton, which serves as a scaffold to sup-port the plasma membrane, and as a network of tracks along which motor proteins transport sub cellular structures. Our research is therefore focused on the mechanics of the cytoskele-ton, with a particular emphasis on microtubules and microtu-bule-based motors.

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  • The PML Grant Program provides financial assistance consistent with the PML mission to support research in the broad areas of mechanical metrology, semiconductors, ionizing radiation physics, medical physics, biophysics, neutron physics, atomic physics, optical technology, optoelectronics, electromagnetics, time and frequency, quantum physics, weights and measures, quantum electrical metrology, temperature, pressure, flow, far UV physics, and metrology with synchrotron radiation.

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  • Exploring enzymatic mechanisms at a molecular level is one of the major challenges in modern biophysics. Based on enzyme structure data, as obtained by X-ray crystallography or NMR spectroscopy, one can suggest how substrates and products bind for catalysis.

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