Xem 1-20 trên 24 kết quả Bone metastases
  • Tham khảo tài liệu 'chapter 094. soft tissue and bone sarcomas and bone metastases (part 2)', y tế - sức khoẻ, y học thường thức phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

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  • Classification Approximately 20 different groups of sarcomas are recognized on the basis of the pattern of differentiation toward normal tissue. For example, rhabdomyosarcoma shows evidence of skeletal muscle fibers with cross-striations; leiomyosarcomas contain interlacing fascicles of spindle cells resembling smooth muscle; and liposarcomas contain adipocytes. When precise characterization of the group is not possible, the tumors are called unclassified sarcomas. All of the primary bone sarcomas can also arise from soft tissues (e.g., extraskeletal osteosarcoma).

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  • Bone Sarcomas Incidence and Epidemiology Bone sarcomas are rarer than soft tissue sarcomas; they accounted for only 0.2% of all new malignancies and 2370 new cases in the United States in 2007. Several benign bone lesions have the potential for malignant transformation. Enchondromas and osteochondromas can transform into chondrosarcoma; fibrous dysplasia, bone infarcts, and Paget's disease of bone can transform into either malignant fibrous histiocytoma or osteosarcoma.

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  • Stage Grouping Stage IA T1 N0 M0 G1,2 low grade Stage IB T2 N0 M0 G1,2 low grade Stage IIA T1 N0 M0 grade G3,4 high Stage IIB T2 N0 M0 G3,4 high grade Stage III T3 N0 M0 Any G Stage IVA T Any N0 M1a Any G Stage IVB T Any N1 M Any Any G Any T N Any M1b Any G Osteosarcoma Osteosarcoma, accounting for almost 45% of all bone sarcomas, is a spindle cell neoplasm that produces osteoid (unmineralized bone) or bone.

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  • Chondrosarcoma Chondrosarcoma, which constitutes ~20–25% of all bone sarcomas, is a tumor of adulthood and old age with a peak incidence in the fourth to sixth decades of life. It has a predilection for the flat bones, especially the shoulder and pelvic girdles, but can also affect the diaphyseal portions of long bones. Chondrosarcomas can arise de novo or as a malignant transformation of an enchondroma or, rarely, of the cartilaginous cap of an osteochondroma. Chondrosarcomas have an indolent natural history and typically present as pain and swelling.

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  • Cancer in the bone may produce osteolysis, osteogenesis, or both. Osteolytic lesions result when the tumor produces substances that can directly elicit bone resorption (vitamin D–like steroids, prostaglandins, or parathyroid hormone–related peptide) or cytokines that can induce the formation of osteoclasts (interleukin 1 and tumor necrosis factor). Osteoblastic lesions result when the tumor produces cytokines that activate osteoblasts. In general, purely osteolytic lesions are best detected by plain radiography, but they may not be apparent until they are 1 cm.

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  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: F-fluoride PET: changes in uptake as a method to assess response in bone metastases from castrate-resistant prostate cancer patients treated with 223Ra-chloride (Alpharadin)

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  • Disease Stage 5-Year Survival, % Stage I 98.8 A: G1,2; T1a,b; N0; M0 B: G1,2; T2a; N0; M0 Stage II 81.8 A: G1,2; T2b; N0; M0 B: G3,4; T1; N0; M0 C: G3,4; T2a; N0; M0 Stage III G3,4; T2b; N0; M0 51.7 Stage IV

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  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Pain in castration-resistant prostate cancer with bone metastases: a qualitative study

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  • Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Pain in castration-resistant prostate cancer with bone metastases: a qualitative study

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  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Bone metastases mimicking Complex Regional Pain Syndrome I: a case report

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  • Sarcomas are rare (

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  • Etiology Humoral hypercalcemia of malignancy (HHM) occurs in up to 20% of patients with cancer. HHM is most common in cancers of the lung, head and neck, skin, esophagus, breast, genitourinary tract, and in multiple myeloma and lymphomas. Several distinct humoral causes of HHM occur, most commonly overproduction of PTHrP. In addition to acting as a circulating humoral factor, bone metastases (e.g., breast, multiple myeloma) may produce PTHrP, leading to local osteolysis and hypercalcemia.

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài:Modeling invasion of metastasizing cancer cells to bone marrow utilizing ecological principles

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  • Twelve studies addressed the contextual influences which hinder or enable the develop- ment of reflection and reflective capability. Several studies explored the effect of context on reflection and reflective thinking. Sobral (2000) found evidence for improved quality of learning as students strive for control of their learning. He suggests that a greater effort at reflection is associated with a more positive learning experience, and that reflection in learning is related to readiness for self- regulated learning, and to the meaningfulness of the experience. Boenink et al.

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  • Neoadjuvant and concurrent luteinising hormone-releasing hormone agonist (LHRHa) therapy is recommended for 3 to 6 months in men receiving radical radiotherapy for locally advanced prostate cancer. Adjuvant hormonal therapy in addition to radical prostatectomy is not recommended, even in men with margin-positive disease, other than in the context of a clinical trial 10 . Adjuvant hormonal therapy is recommended for a minimum of 2 years in men receiving radi- cal radiotherapy for locally advanced prostate cancer who have a Gleason score of ≥ 8.

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  • As mentioned in Appendix 2.2, it is recommended that cancer registries use the International Classification of Diseases for Oncology (ICD-O) (Percy et al., 1990) to code the topography (site of primary tumour) and morphol- ogy (histological type) of the tumours. The fifth digit in the ICD-O mor- phology codes describes the behaviour of the tumour—benign, borderline, in situ, malignant. The topography of a tumour is the most important data item recorded and provides the main basis of tabulation of registry data....

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  • Tobacco smoke is highly addictive and has been linked to 20 percent of all deaths in the United States. It contains many cancer- causing chemicals, and almost one third of all cancer deaths are related to tobacco use. Tobacco smoking has generally been considered to have little or no association with breast cancer risk. Newer studies have challenged this conclusion and suggested a connection between smoking and an increased risk of breast cancer, but more investigation is needed to resolve this issue.

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  • The experience of breast cancer can also create challenges for a marriage or signif- icant relationship. Difficulties include communication problems, difficulty coping and sexual dysfunction (one study found that approximately 50% of women with cancer had at least one diagnosed sexual dysfunction during the posttreatment year) (Anderson,Ander- son, & DeProsse, 1989). However, research suggests that when marriages are strong before the development of breast cancer, the disease does not usually disrupt the relation- ship, and may result in an even closer relationship (Oktay & Walter, 1991).

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  • Staging of Small Cell Lung Cancer Pretreatment staging for patients with SCLC includes the initial general lung cancer evaluation with chest and abdominal CT scans (because of the high frequency of hepatic and adrenal involvement) as well as fiberoptic bronchoscopy with washings and biopsies to determine the tumor extent before therapy; brain CT scan (10% of patients have metastases); and radionuclide scans (bone) if symptoms or other findings suggest disease involvement in these areas.

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