Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Global transcriptional responses of fission and budding yeast to changes in copper and iron levels: a comparative study...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: High-resolution transcription atlas of the mitotic cell cycle in budding yeast...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Heterochronic evolution reveals modular timing changes in budding yeast transcriptomes...
Cells of the budding yeast, S. cerevisiae, have for several decades now been considered
as the prototypic eukaryotic cells, ideally suited to study and uncover many
of the basic phenomena of eukaryotic life.
Prions are infectious proteins, in which self-propagating amyloid conforma-tions of proteins are transmitted. The budding yeast Saccharomyces cerevi-siae, one of the best-studied model eukaryotes, also has prions, and thus
provides a tractable model system with which to understand the mechanisms
of prion phenomena.
Ubiquinone is an essential factor for the electron transfer system and is
also a known lipid antioxidant. The length of the ubiquinone isoprenoid
side-chain differs amongst living organisms, with six isoprene units in the
budding yeastSaccharomyces cerevisiae, eight units in Escherichia coliand
10 units in the fission yeast Schizosaccharomyces pombeand in humans.
The functional expression of olfactory receptors (ORs) is a primary require-ment to examine the molecular mechanisms of odorant perception and cod-ing. Functional expression of the rat I7 OR and its trafficking to the
plasma membrane was achieved under optimized experimental conditions in
the budding yeast Saccharomyces cerevisiae. The membrane expression of
the receptor was shown by Western blotting and immunolocalization meth-ods.
Mitochondrial ribosomal proteins (mrps) of the budding
yeast, Saccharomyces cerevisiae, have been extensively
characterized genetically and biochemically. However, the
list of thegenes encoding individualmrps is still not complete
and quite a fewof the mrps are only predicted from their
similarity to bacterial ribosomal proteins. We have con-structed a yeast strain in which one of the small subunit
proteins, termed Mrp4, was tagged with S-peptide and used
for affinity purification of mitochondrial ribosome. ...
DNA replication, the process of copying one double stranded DNA molecule to produce two identical copies, is at the heart of cell proliferation. This book highlights new insights into the replication process in eukaryotes, from the assembly of pre-replication complex and features of DNA replication origins, through polymerization mechanisms, to propagation of epigenetic states. It also covers cell cycle control of replication initiation and includes the latest on mechanisms of replication in prokaryotes. The association between genome replication and transcription is also addressed.
It has been widely accepted that most coenzyme Q (CoQ) exists freely in
the mitochondrial membrane as a CoQ pool. However, the recent identifi-cation of a mitochondrial CoQ-binding protein, termed Coq10, in budding
yeast has the potential to change our current view of CoQ status in mem-branes.
Mitotic chromosome structure depends on the chromosomal condensin complex. Without condensin, metaphase chromosomes remain
undercondensed and lack structural stability. We have asked where along budding yeast chromosomes the condensin complex associates,
and what we can learn from its binding pattern about the mechanism of chromosome condensation.
Septins are a family of conserved proteins that are essential for cytokinesis
in a wide range of organisms including fungi, Drosophila and mammals. In
budding yeast, where they were first discovered, they are thought to form a
filamentous ring at the bridge between the mother and bud cells.
The centromere–kinetochore complex is a highly specialized chromatin domain that both mediates and monitors chromosome–spindle interactions responsible for accurate partitioning of sister chromatids to daughter cells. Centromeres are distinguished from adjacent chromatin by speciﬁc patterns of histone modiﬁcation and the presence of a centromere-speciﬁc histone H3 variant (e.g. CENP-A). Centromere-proximal regions usually correspond to sites of avid and persistent sister chromatid cohesion mediated by the conserved cohesin complex.
DNA replication is restricted to a specific time window of the cell cycle, called S phase. Successful
progression through S phase requires replication to be properly regulated to ensure that the entire
genome is duplicated exactly once, without errors, in a timely fashion. As a result, DNA replication
has evolved into a tightly regulated process involving the coordinated action of numerous factors that
function in all phases of the cell cycle. Biochemical mechanisms driving the eukaryotic cell division
cycle have been the subject of a number of mathematical models.
In eukaryotes, two heteroheptameric Sm-like (Lsm) complexes that differ
by a single subunit localize to different cellular compartments and have dis-tinct functions in RNA metabolism. The cytoplasmic Lsm1–7p complex
promotes mRNA decapping and localizes to processing bodies, whereas the
Lsm2–8p complex takes part in a variety of nuclear RNA processing
In budding yeast, the protein phosphatase Cdc14 is a key regulator of late
mitotic events. Research over the last decade has revealed many of its func-tions and today we know that this protein phosphatase orchestrates several
aspects of chromosome segregation and is the key trigger of exit from
The budding yeastSaccharomyces cerevisiaepossesses a very flexible and
complex programme of gene expression when exposed to a plethora of
environmental insults. Therefore, yeast cell homeostasis control is achieved
through a highly coordinated mechanism of transcription regulation invol-ving several factors, each performing specific functions. Here, we present
our current knowledge of the function of the yeast activator protein family,
formed by eight basic-leucine zipper trans-activators, which have been
shown to play an important role in stress response....
Thuật ngữ Nấm men (yeast, levure) chỉ là tên chung để chỉ nhóm vi nấm thường có cấu tạo đơn bào và thường sinh sôi nảy nở bằng phương pháp nẩy chồi (budding). Nấm men không thuộc về một taxon phân loại nào nhất định, chúng có thể thuộc ngành Nấm túi (Ascomycota) hoặc ngành Nấm đảm (Basidiomycota).
A. PHÂN LOẠI NẤM MEN Thuật ngữ Nấm men (yeast, levure) chỉ là tên chung để chỉ nhóm vi nấm thường có cấu tạo đơn bào và thường sinh sôi nảy nở bằng phương pháp nẩy chồi (budding). Nấm men không thuộc về một taxon phân loại nào nhất định, chúng có thể thuộc ngành Nấm túi (Ascomycota) hoặc ngành Nấm đảm (Basidiomycota). Nảy chồi là cách sinh sản vô tính điển hình của nấm men. Khi đó thành tế bào mở ra để tạo ra một chồi (bud).