Cancer anorexia

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  • The International Agency for Research on Cancer (IARC, World Health Organization) [ 1 ] estimated an incidence of 6,617,855 cancers around the world in 2008 with 4,219,626 deaths associated with this disease (IARC 2011).

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  • The cancer registry is an essential part of any rational programme of can- cer control. Its data can be used in a wide variety of areas of cancer control ranging from etiological research, through primary and secondary preven- tion to health-care planning and patient care. Although most cancer reg- istries are not obliged to do more than provide the basis for such uses of the data, they possess the potential for developing and supporting important research programmes making use of the information they collect....

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  • Irene J Higginson MD PhD is Professor of Palliative Care and Policy and Head of the Department of Palliative Care and Policy, King’s College, London. She qualified in medicine from Nottingham University, and has worked in wide-ranging medical and university positions, including radiotherapy and oncology, in-patient and home hospice care, at the Department of Health (England) and various universities.

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  • The aim of this chapter is to summarize and evaluate the different mechanisms and catabolic mediators involved in cancer cachexia and ageing sarcopenia since they may represent targets for future promising clinical investigations. Cancer cachexia is a syndrome characterized by a marked weight loss, anorexia, asthenia and anemia. In fact, many patients who die with advanced cancer suffer from cachexia. The degree of cachexia is inversely correlated with the survival time of the patient and it always implies a poor prognosis.

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  • Marasmus The end stage of cachexia, marasmus is a state in which virtually all available body fat stores have been exhausted due to starvation. Conditions that produce marasmus in developed countries tend to be chronic and indolent, such as cancer, chronic pulmonary disease, and anorexia nervosa. Marasmus is easy to detect because of the patient's starved appearance. The diagnosis is based on severe fat and muscle wastage resulting from prolonged calorie deficiency.

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  • Câu: "trừ giai đoạn terminal" có lẽ không đúng, và statement "các cách này...không thể dùng cho cancer đuợc" có lẽ cũng không đúng. Vì mechanism cuả anorexia và sự tăng trưởng (hoặc chết) cuả tế bào ung thư theo các cơ chế hoàn toàn khác nhau. Dù rằng các studies trong hơn hai mươi năm qua cho thấy có liên hệ chăt chẽ giưã phản ứng cuả cơ thể (ăn mất ngon) và ung thư (trong một bài trước đã trích dẫn, bài trong Clinical Nutrition - Europe, chẳng hạn). ...

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