There have been a significant number of advances
in the field of cancer research since the
first edition of Cancer Biology, which was published
in 1981. These include advances in defining
the genetic and phenotypic changes in cancer
cells, the genetic susceptibility to cancer, molecular
imaging to detect smaller and smaller tumors,
the regulation of gene expression, and the
‘‘-omics’’ techniquesofgenomics, proteomics,and
metabolomics, among others.
The last three decades have witnessed tremendous advances in the understanding
and treatment of breast cancer. As a result, starting shortly before the 1990s, a persistent
decrease in breast cancer mortality has been documented, primarily in the
United States and in several European countries. Breast cancer, however, remains
an important health problem. In this book, which is mainly dedicated to nuclear
medicine, experts have thoroughly reviewed the achievements made in the diagnosis,
monitoring and treatment of this disease.
Today, cancer research is focused on determining how genome and proteome level
information may be useful as tools in prevention, diagnosis, and prognosis. The
development of “omics” technologies, such as proteomics and transcriptomics has
opened new research areas for scientists working on cancer research.
For tracking the marketing related behaviors
of online communities, “netnography” is a
stand-alone method. It is a way in which to
understand the discourse and interactions of
people engaging in computer-mediated
communication about market-oriented topics.
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Technical phosphoproteomic and bioinformatic tools useful in cancer research...
While researching this book, I came across a letter in the journal Nature asking for
caution in the current trend for the use of humorous nomenclature for newly
discovered genes1, the author referring to the tumour suppressor gene Pokemon,
which I have briefly described in Chapter 4.
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Science, institutional archives and open access: an overview and a pilot survey on the Italian cancer research institutions
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: New perspectives on an old disease: proteomics in cancer research...
Historically, most cancer research has been conducted through
small independent projects initiated by individual investigators
with relatively small research groups. Such research is driven
by focused hypotheses addressing specific biological questions. There will
always be a need for this traditional approach to research; in recent years,
however, it has also become more feasible to undertake projects on a
broader and larger scale, thereby developing extensive pools of data and
research tools that can facilitate those more conventional efforts....
Cancer, although a dreadful disease, is at the same time a fascinating biological
phenotype. Around 1980, cancer was first attributed to malfunctioning genes and,
subsequently, cancer research has become a major area of scientific research supporting
the foundations of modern biology to a great extent. To unravel the human
genome sequence was one of those extraordinary tasks, which has largely
been fuelled by cancer research, and many of the fascinating insights into the
genetic circuits that regulate developmental processes have also emerged from
research on cancer....
Population-based cancer registries are important resources for cancer epi-
demiologists since they hold information on the distribution of cancer in well
defined populations. This information may be analysed without the need for
any additional data collection. Cancer site-specific incidence rates can be cal-
culated and compared according to many different variables such as age, sex,
country of birth, place of residence at the time of diagnosis, etc.
HeR2 status. Your pathology report
usually includes the cancer’s HER2
status. The HER2 gene is responsible for
making HER2 proteins. These proteins
are receptors on breast cells. Under
normal circumstances, HER2 receptors
help control how a breast cell grows,
divides, and repairs itself. But in about
25% of breast cancers, the HER2 gene
can become abnormal and make too
many copies of itself (amplification of
the HER2 gene). Amplified HER2 genes
command breast cells to make too
many receptors (overexpression of the
This second edition of Breast Cancer continues the tradition of the M. D.Anderson Cancer Care Series. The book is oriented towards the needs of clinicians who manage breast cancer at every stage of the disease. Chapters are written by experts with a strong knowledge of research findings who also are active in the clinic and understand the practical needs of the patient and her physician.
According to the National Cancer Institute, cancer continues to take
a devastating toll. Among women in the United States, cancer is the
second-leading cause of death after heart disease. Medical researchers
fighting against cancer have made significant progress, however. In
recent years, cancer incidence rates have been stable, and—although
the annual rate of decline in cancer death rates among men have been
twice as large as the declines in women—mortality has decreased for
ten of the top 15 cancers in women.
This is a book about the most fearsome disease of modern times, which will strike every fourth
citizen of a developed country sometime during his life: cancer. It is not a book about the prevention
of cancer, but rather its treatment with plant-derived chemicals. It is an up-to-date and
extensive review of plant genera and species with antitumor and antileukemic properties that
have been documented in a strictly scientific sense.
From within the small yet growing body of research focused upon CAM use for pregnancy
[2,5], the majority has examined pregnant women’s use of discrete supplements or treatments
and, despite recommendations [23,24], there has been little exploration of women’s
consultations with CAM practitioners. One exception is a recent longitudinal cohort study
(n=535)  which identified no significant change in this prevalence rate over a 10 year
period compared with non-pregnant women.
There is growing evidence on the importance of studies focusing on mechanisms and
strategies leading to cancer prevention. The plethora of approaches include regulation
of oxidative stress using antioxidant therapies, carefully balanced diets and living
habits, epidemiological evidence and molecular approaches on the role of key
biological molecules such as antioxidant enzymes, vitamins, proteins and naturally
occurring free radical scavengers as well as controversial results and clinical
applications. These are some of the topics that this book highlights.
Veterinary medicine is advancing at a very rapid pace, particularly given the breadth
of the discipline. This book examines new developments covering a wide range of
issues from health and welfare in livestock, pets, and wild animals to public health
supervision and biomedical research.
As well as containing reviews offering fresh insight into specific issues, this book
includes a selection of scientific articles which help to chart the advance of this science.
The book is divided into several sections.