Xem 1-15 trên 15 kết quả Cannabinoid receptors
  • Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Functional Role of Serine Residues of Transmembrane Dopamin VII in Signal Transduction of CB2 Cannabinoid Receptor

    pdf7p hoami_266 15-09-2011 20 2   Download

  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis...

    pdf14p thulanh14 15-10-2011 24 2   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Effect of the Cannabinoid Receptor-1 antagonist SR141716A on human adipocyte inflammatory profile and differentiation...

    pdf38p thulanh26 09-12-2011 17 2   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation

    pdf13p panasonic09 12-01-2012 17 2   Download

  • The endocannabinoid system is a conserved system involved in the modula-tion of several physiologic processes, from the activity of the central ner-vous system to reproduction. Type 1 cannabinoid receptor (CNR1) cDNA was cloned from the brain and testis of the anuran amphibian, the frog Rana esculenta.

    pdf12p galaxyss3 19-03-2013 10 2   Download

  • Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: SR144528 as Inverse Agonist of CB2 Cannabinoid Receptor

    pdf6p hoami_266 15-09-2011 10 1   Download

  • We have investigated the existence of a precoupled form of the distal C-ter-minal truncated cannabinoid receptor 1 (CB1-417) and heterotrimeric G proteins in a heterologous insect cell expression system. CB1-417 showed higher production levels than the full-length receptor. The production lev-els obtained in our expression system were double the values reported in the literature.

    pdf10p media19 05-03-2013 5 1   Download

  • Loss of cannabinoid receptors (CB1) occurs prior to neuro-degeneration in Huntington’s disease (HD). The levels and distribution of CB1 RNA were equivalent in 3-week-old mice regardless of genotype demonstrating that the specific factors and appropriate chromatin structure that lead to the transcription ofCB1were present in the striatum of young R6/2 and R6/1 transgenic HD mice.

    pdf12p awards 05-04-2013 16 1   Download

  • The last decade or so has seen remarkable advances in our knowledge of cough. This applies especially to its basic mechanisms: the types of airway sensors, the pharmacological receptors on their membranes, the brainstem organization of the ‘cough centre’, and the involvement of the cerebral cortex in the sensations and the voluntary control of cough. With the exception of the last of these, nearly all the studies have been on experimental animals rather than humans, for obvious reasons.

    pdf380p mnemosyne75 02-02-2013 17 4   Download

  • Less than 20 years ago the field of cannabis and the cannabinoids was still considered a minor, somewhat quaint, area of research. A few groups were active in the field, but it was already being viewed as stagnating. The chemistry of cannabis was well known, Δ9-tetrahydrocannabinol (Δ9-THC), identified in 1964, being the only major psychoactive constituent and cannabidiol, which is not psychoactive, possibly contributing to some of the effects. These cannabinoids and several synthetic analogs had been thoroughly investigated for their pharmacological effects.

    pdf754p mnemosyne75 02-02-2013 15 3   Download

  • Public opinion on the medical value of marijuana has been sharply divided. Some dismiss medical marijuana as a hoax that exploits our natural compassion for the sick; others claim it is a uniquely soothing medicine that has been withheld from patients through regulations based on false claims. Proponents of both views cite “scientific evidence” to support their views and have expressed those views at the ballot box in recent state elections.

    pdf286p camchuong_1 10-12-2012 20 1   Download

  • The life cycle of the retrovirus consist of several steps. It begins with the binding of the viral envelope to cellular receptors, which enables fusion of the viral envelope with the cellular membrane. Consequently, the viral particle is uncoated, liberating the viral core into the cell cytoplasm. The viral DNA is reverse transcribed to DNA. Then, the viral DNA is transported to the nucleus where it is integrated into the host cell’s genome. From there, viral DNA is transcribed to RNA, some of which is translated to proteins.

    pdf602p kmkmkmkmkm 08-09-2012 21 10   Download

  • Cannabinoid receptors and their endogenous ligands, the endocannabinoids, have been detected in several blood immune cells, including monocytes/macrophages, basophils and lymphocytes. However, their presence in dendritic cells, which play a key role in the initiation and development of the immune response, has never been investigated.

    pdf8p system191 01-06-2013 10 2   Download

  • An emerging body of evidence supports a key role for the endocannabinoid system in numerous physiological and pathological mechanisms of the cen-tral nervous system. In the recent past, many experimental studies have examined the putative protective or toxic effects of drugs interacting with cannabinoid receptors or have measured the brain levels of endocannabi-noids inin vitro and in vivo models of cerebral ischemia.

    pdf11p vinaphone15 27-02-2013 15 1   Download

  • Anandamide is an endogenous ligand for cannabinoid receptor and its protein-mediated transport across cellular membranes has been demonstrated in cells derived from brain as well as in cells of the immune system. This lipid is inactivated via intracellular degradation by a fatty acid amidohydrolase (FAAH). In the present study, we report that rabbit platelets, in contrast to human platelets, do not possess a carrier-mediated mechanism for the transport of [ 3 H]anandamide into the cell, i.e. cellular uptake was not temperature dependent and its accumulation was not satu-rable. ...

    pdf9p tumor12 20-04-2013 11 1   Download

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