Cardiac drugs

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  • The impetus to provide a seventh edition of Cardiac Drug Therapy was generated by the positive comments received from readers worldwide, and from favorable reviews of earlier editions. The seventh edition updates and revises the sixth edition in several respects. In particular, the text includes: Six new chapters that deal with ongoing important controversies regarding the use of several widely used cardiac drugs. Controversies have arisen regarding the use of beta blockers for the treatment of hypertension.

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  • Drugs for the Treatment of Peptic Ulcers cipitated antacid or, phosphate depletion of the body with excessive intake of Al(OH)3. Na+ ions remain in solution even in the presence of HCO3–-rich pancreatic secretions and are subject to absorption, like HCO3–. Because of the uptake of Na+, use of NaHCO3 must be avoided in conditions requiring restriction of NaCl intake, such as hypertension, cardiac failure, and edema. Since food has a buffering effect, antacids are taken between meals (e.g., 1 and 3 h after meals and at bedtime). Nonabsorbable antacids are preferred.

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  • Introduction: Oleander (Nerium oleander and Nerium indicum) is a relatively small evergreen tree of an Indian origin, and growing in Honshu, Shikoku, Kyushu and Okinawa islands in Japan. The plant contains cardiac glycosides in its leaves, stems and flowers and is known as one of poisonous plants; poisoning and fatal cases for domestic animals and humans due to ingestion of this plant were reported [1–6]. The main toxin of oleander is oleandrin. Oleandrin can be measured using cross-reaction of an immunoassay kit for digoxin [1], TLC [2], HPLC [7, 8] and LC/MS [3, 6].

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  • Introductio: β-Blockers (β-adrenergic receptor antagonists) block the effects of catecholamines on signal transmission through β-receptors; they cause hypotension by decreasing the heart beat rate and cardiac output, and prevent the attacks of arrhythmia and angina pectoris. In the brain, the drugs attenuate migraine by suppressing the dilation of blood vessels; in the eye, they decrease intraocular pressure by suppressing the production of aqueous humor.

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  • In many countries, medicine is at present facing urgent political and economic calls for reform. These socioeconomic pressures notwithstanding, pharmacotherapy has always been an integral part of the health care system and will remain so in the future. Well-founded knowledge of the preventive and therapeutic value of drugs is a sine qua non for the successful treatment of patients entrusting themselves to a physician or pharmacist. Because of the plethora of proprietary medicines and the continuous influx of new pharmaceuticals, the drug market is dif cult to survey and hard to understand.

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  • Our main purpose in editing this book is to provide the health care practitioner with general clinical practical guidelines regarding the use of pediatric cardiovascular drugs. We also intend to provide an overview of basic pediatric cardiovascular principles. We realize the need for a pocket reference handbook that is tailored to meet the daily challenges of practitioners that care for pediatric cardiac patients.

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  • The pathophysiology of cardiac arrhythmias is complex and the actions of drugs that are useful in stopping or controlling them may seem equally so. Nevertheless many patients with arrhythmias respond well to therapy with drugs and a working knowledge of their effects and indications pays dividends, for irregularity of the heart-beat is at least inconvenient and at worst fatal.The mechanisms by which the failing heart may be sustained are now better understood; carefully selected and monitored drugs can have a major impact on morbidity and mortality in this condition.

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  • Valproic acid, a widely used anticonvulsant drug, is a potent teratogen resulting in various congenital abnormalities. However, the mechanisms underlying valproic acid induced teratogenesis are nor clear. Recent studies indicate that histone deacetylase is a direct target of valproic acid. Methods: In the present study, we have used histological analysis and RT-PCR assays to examine the cardiac abnormalities in mice treated with sodium valproate (NaVP) and determined the effects of NaVP on histone deacetylase activity and the expression...

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  • The theory of neurohumoral transmission received direct experimental validation nearly a century ago (see von Euler , 1981 ), and extensive investigation during the ensuing years led to its general acceptance. Nerves transmit information across most synapses and neuroeffector junctions by means of specific chemical agents known as neurohumoral transmitters or, more simply, neurotransmitters.

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  • Tham khảo sách 'color atlas of pharmacology 3rd edition', y tế - sức khoẻ, y học thường thức phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

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  • The incidence of cardiovascular disease has decreased in the last several years with a better understanding of the pathophysiology of acute coronary syndromes (ACS), widespread implementation of lipid lowering drugs, improved surgical treatments such as stent placements, and new therapeutic regimens such as the statins, low molecular weight heparins, and platelet glycoprotein IIb/IIIa receptor inhibitors. Nevertheless, it remains today as the leading cause of morbidity and mortality in the Western world....

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  • Health insurance makes a difference in whether and when people get necessary medical care, where they get their care, and ultimately, how healthy people are. Uninsured adults are far more likely than the insured to postpone or forgo health care altogether and less able to afford prescription drugs or follow through with recommended treatments. Problems getting needed care are less common among children, who are generally healthy, but disparities in access to care between uninsured and insured children are as great as the adult differences.

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care cung cấp cho các bạn kiến thức về ngành y đề tài: Bench-to-bedside review: Inotropic drug therapy after adult cardiac surgery – a systematic literature review...

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  • Tài sản của tĩnh mạch GP IIb / IIIa Antagonists Năm Abciximab Nhà cung cấp thương mại tên của trọng lượng phê duyệt integrin Cơ cấu chọn lọc phân tử (kDa) Plasma một nửa cuộc sống chỉ bài tiết được phê duyệt chấp thuận

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  • Bệnh mạch máu ngoại biên (PVD). Nếu một beta-blocker là cần thiết trong một bệnh nhân với PVD, một số thử nghiệm lâm sàng cho thấy rằng nó là an toàn hơn để sử dụng một loại thuốc cardioselective, atenolol, metoprolol; các đại lý như carvedilol hoặc bucindolol rằng giãn mạch gây ra có thể có một vai trò.

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  • Tại Hoa Kỳ, thuốc này được chấp thuận cho sử dụng đường uống ở bệnh nhân loạn nhịp thất đe dọa tính mạng (duy trì VT). Đại lý này không được khuyến cáo để điều trị nhịp tâm thất không có triệu chứng sớm.

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  • Với isradipine và felodipin, tương tác xảy ra với cimetidine, các thuốc chống động kinh, và nước bưởi. Felodipine (Plendil) là chất đối kháng canxi được sử dụng trong điều trị cao huyết áp tối ưu (HOT) nghiên cứu (27).

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  • Sự mất cân bằng mất nước và điện giải là những tác dụng phụ phổ biến nhất. Liều quá lớn nếu các dấu hiệu của mất nước hoặc hạ huyết áp tư thế đứng phát triển, hoặc nếu bệnh nhân đã tăng urê 10.0 mmol / L hoặc tăng 7,0 mmol / L so với ban đầu, mg 7 clorua 32 mEq (mmol) / L, và acid uric / dL (420 mmol / L)

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  • Thực phẩm và Dược là một liều tải 300 mg clopidogrel, nhưng các hướng dẫn cho PCI được phát hành bởi Hiệp hội Tim mạch châu Âu (62) giới thiệu 600 mg ở bệnh nhân với NSTEM và đau thắt ngực không ổn định dự kiến ​​sẽ ngay lập tức

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  • IV thuốc đối kháng canxi ức chế kênh canxi hạn chế chậm canxi hiện tại một tranh cãi. Thay đổi từ EM Vaughan Williams. Phân loại các thuốc chống loạn nhịp. Sandhoe E, FlenstedJensen E, Olesen KH, eds. Hội nghị chuyên đề về rối loạn nhịp tim. Sodertalje,

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