High-density lipoprotein (HDL) cholesterol levels are a strong inverse predictor of
cardiovascular events. However, it is not clear whether this association is maintained
at very low levels of low-density lipoprotein (LDL) cholesterol.
A post hoc analysis of the recently completed Treating to New Targets (TNT) study
assessed the predictive value of HDL cholesterol levels in 9770 patients.
The Fédération Internationale de Football Association (FIFA) World Cup, held in
Germany from June 9 to July 9, 2006, provided an opportunity to examine the relation
between emotional stress and the incidence of cardiovascular events.
Cardiovascular events occurring in patients in the greater Munich area were prospectively
assessed by emergency physicians during the World Cup. We compared
those events with events that occurred during the control period: May 1 to June 8
and July 10 to July 31, 2006, and May 1 to July 31 in 2003 and 2005....
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Predictors of the first cardiovascular event in patients with systemic lupus erythematosus - a prospective cohort study...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Prospective cohort studies on risk factors for cardiovascular events in systemic lupus erythematosus: a major challenge...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Cardiovascular events in early RA are a result of inflammatory burden and traditional risk factors: a five year prospective study...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: A cost-minimization analysis of diuretic-based antihypertensive therapy reducing cardiovascular events in older adults with isolated systolic hypertension...
A person who had the cancer and died 10 years later of the cancer would
contribute an event, a death due to the cancer, having also contributed 10 person-years of
survival time. A 90 % cancer specific survival at 10 years would mean that 90 % of patients
had not died from their cancer, while 10 % had died from their cancer (Kaplan, 1958).
Calculation of cause-specific survival is especially important when studying diseases with a
favorable prognosis, as is the case at hand, where the patients live long enough to be
exposed to other causes of death....
In 1856, Rudolf Virchow published “Cellular pathology” based on macroscopic and
microscopic observation of diseases, and described a triad of factors on thrombosis. The
three components were vascular change, blood flow alteration, and abnormalities of blood
constituents. Although Virchow originally referred to venous thrombosis, the theory can
also be applied to arterial thrombosis, and it is considered that atherothrombus formation is
regulated by the thrombogenicity of exposed plaque contents, local hemorheology, and
This article argues that the crisis of 2007–2008 happened because of an explosive
combination of agency problems, moral hazard, and “scientism”—the illusion that
ostensibly scientiﬁc techniques would manage risks and predict rare events in spite
of the stark empirical and theoretical realities that suggested otherwise. The authors
analyze the varied behaviors, ideas and effects that in combination created a ﬁnancial
meltdown, and discuss the players responsible for the consequences.
The workplace as a health promotion setting
Workplace health promotion (WHP) programmes, targeting physical
inactivity and unhealthy dietary habits, are effective in improving health-
related outcomes such as obesity, diabetes and cardiovascular disease
risk factors. Enhancing employee productivity, improving corporate
image and moderating medical care costs are some of the arguments
that might foster senior management to initiate and invest in WHP
Medical Implications of Circadian Rhythmicity
Prominent circadian variations have been reported in the incidence of acute myocardial infarction, sudden cardiac death, and stroke, the leading causes of death in the United States. Platelet aggregability is increased after arising in the early morning hours, coincident with the peak incidence of these cardiovascular events. A better understanding of the possible role of circadian rhythmicity in the acute destabilization of a chronic condition such as atherosclerotic disease could improve the understanding of the pathophysiology.
In patients with stable coronary artery disease, it remains unclear whether an initial
management strategy of percutaneous coronary intervention (PCI) with intensive
pharmacologic therapy and lifestyle intervention (optimal medical therapy) is superior
to optimal medical therapy alone in reducing the risk of cardiovascular events.
We conducted a randomized trial involving 2287 patients who had objective evidence
of myocardial ischemia and significant coronary artery disease at 50 U.S. and Canadian
(BQ) Part 1 book "Netter's atlas of human embryology" presents the following contents: An overview of developmental events, processes and abnormalities, early embryonic development and the placenta, the nervous system, the cardiovascular system, the respiratory system.
The Women’s Health Study, which included almost 40,000 healthy women at least 45 years
of age, found that vitamin E supplements did not reduce the risk of heart attack, stroke,
cancer, age-related macular degeneration, or cataracts. Although vitamin E supplements
were associated with fewer deaths from cardiovascular causes, they did not reduce the
overall death rate of study participants.
The Physicians’ Health Study II, which included more than 14,000 male physicians aged 50
or older, found that neither vitamin E nor vitamin C supplements reduced the risk of major
cardiovascular events (heart attack, stroke, or death from cardiovascular disease), cancer,
or cataracts. In fact, vitamin E supplements were associated with an increased risk of
hemorrhagic stroke in this study.
Calcified plaque in the coronary arteries is a marker for atheromatous-plaque burden
and is predictive of future risk of cardiovascular events. We examined the relationship
between estrogen therapy and coronary-artery calcium in the context of a randomized
In our ancillary substudy of the Women’s Health Initiative trial of conjugated equine
estrogens (0.625 mg per day) as compared with placebo in women who had undergone
hysterectomy, we performed computed tomography of the heart in 1064 women
aged 50 to 59 years at randomization.
Few studies have simultaneously investigated the role of soluble tumor necrosis factor
) receptors types 1 and 2 (sTNF-R1 and sTNF-R2), C-reactive protein, and
interleukin-6 as predictors of cardiovascular events. The value of these inflammatory
markers as independent predictors remains controversial.
After completing this chapter, students will be able to: Describe the structural and functional properties of cardiac muscle, and explain how it differs from skeletal muscle; briefly describe the events of cardiac muscle cell contraction; name the components of the conduction system of the heart, and trace the conduction pathway;...