Diabetes-related cardiovascular complications often cause premature mortality,
as well as disabilities such as blindness, foot ulceration and amputation.
The health care and social care costs of managing these complications are
enormous, but new treatments, devices and clinical management protocols
are steadily improving the longer term outcomes for people with diabetes.
This second edition has been revised and updated to reflect state of the art
The last quarter of a century has seen dramatic
developments in the management of cardiovascular
diseases. Besides the pioneering developments in
the medical management of cardiovascular disorders
the field of interventional cardiology has also emerged
as a major discipline with a huge impact on the
clinical management of acute coronary syndrome,
chronic coronary artery disease, congestive heart
failure, and peripheral vascular and valvular diseases.
Stem cell research has the potential to affect the lives of millions
of people in the United States and around the world.
This research is now regularly front-page news because of the
controversy surrounding the derivation of stem cells from
human embryos. Realizing the promise of stem cells for
yielding new medical therapies will require us to grapple with
more than just scientific uncertainties. The stem cell debate
has led scientists and nonscientists alike to contemplate
profound issues, such as who we are and what makes us
The First Conference of French-Speaking African Countries on Men’s Participation in
Reproductive Health was held in Ouagadougou, Burkina Faso from March 30 to April 3,
1998. It was organized to share experiences and lessons learned over the past decade
among African organizations about communicating with men on reproductive health
Pediatric cardiology section enlightens us on cardiovascular changes in fetuses /
infants as well as some pediatric cardiovascular surgical procedures needing skill
under recent developments. Pediatric hemato-oncology section explains novel
developments of well-known diseases such as neuroblastoma and thalassemias. For
instance; whole genome searches and molecular basis for diagnosis of neuroblastoma
are discussed. However, this section also includes some common complications of
oncology e.g. fertility and fatigue seen in these patients.
Bladder, uterine, and rectal prolapse are common sequelae of childbirth.
Sometimes bulging is obvious on initial inspection, but other times it may
only be evident when the patient bears down as if she were attempting to void
and then defecate. The examiner should be appropriately positioned before
undertaking this evaluation, because some women will lose urine with this
maneuver. For many women with prolapse, diagnosis is only possible after a
more detailed gynecologic examination (see Chapters 10 and 14)....
Therapeutic immunosuppression has very broad applications in clinical medicine,
ranging from prevention and treatment of organ and bone marrow transplant
rejection, management of various autoimmune disorders (e.g., rheumatoid arthritis),
skin diseases, allergies and asthma. Whereas traditionally only a small repertoire of
immunosuppressive agents was available for clinical use, recent discoveries have
significantly increased the number of approved agents, resulting in numerous trials to
further evaluate their potential.
The scientific and lay media extol the health benefits of good nutrition and physical
activity. Most books that have been published about nutrition and physical activity
have dealt with nutritional needs of young adults who exercise vigorously. At around
30 years of age or so, individuals start to become more concerned about having and
maintaining good health and realizing the personal benefits of good nutrition and
moderate-intensity physical activity. Some health professionals seem to believe that
nutrition and physical activity information is the same for all people.
Therefore, this book tried to incorporate into its own matrix the crucial issues that are
recent contributions to learning less frequent topics, with very promising therapy
approaches. So the aim and the project was at the final the scope of the title “Allergic
diseases - highlights in the clinic, mechanisms and treatment”, since it would not be
possible to materialize a project that seeks to be a formal Medical Treaty covering the
full breadth and complexity of allergy. Nevertheless, this book provides an accurate
and current learning of many clinical issues....
Several of the success stories highlighted in the Law Enforcement Cases section are
groundbreaking cases in the use of charging and in successful convictions. Of
particular note, we discuss a conviction on structuring charges where there was no
allegation that the funds were illegally derived.
In Issues & Guidance, we present an article on the value of BSA data that provides
material that BSA Compliance Officers may consider adapting for use when
addressing their Boards of Directors.
Populations on dialysis are showing a rapid worldwide increase. In developed countries,
remarkable increases in elderly patients and those with diabetes have been noted. In devel‐
oping countries, changes in life style and economic development have made hemodialysis
(HD) therapy available to many more patients. In this special issue, reviews of various as‐
pects of HD therapy were submitted from both groups. In particular, various methods for
vascular access were discussed by many contributors. From these reviews, the reader will
In 1990, four of the ten leading causes of death in American women were chronic diseases
directly associated with modifiable behavioral factors including physical inactivity or
sedentary lifestyle. They were heart disease, certain forms of cancer (specifically, breast and
colon cancers), cerebrovascular disease (hypertension and stroke), and non-insulin-dependent
diabetes mellitus (NIDDM) (National Center for Health Statistics, 1993).
The basic human right of self-determination is meaningless for women
who do not have the ability to control reproduction. Devoting an issue of
this journal to contraception makes sense at this time when the unintended
pregnancy rate in the United States continues to hover at 50%. Every
woman knows whether it is the right time for her to bear a child and for
her and her family to commit the considerable personal and financial resources
necessary for raising that child. But the impact of contraception
transcends the importance of individual choice.
Surgical education is changing. Mandates that foster this change include increasing
demands from the public for perfection without practice, decreasing
trainee work hours, increasing minimally invasive therapies, and fewer surgical
educators. In addition, rising health care costs have caused many experienced
surgeons to focus on patient care rather than the mentoring of surgical trainees. A
paradigm shift in surgical education is being forced by all these issues.
The 10 problems of least concern are generally issues of limited exposure to most small-busi-
ness owners and typically find themselves at the bottom of the ranking each year. Three prob-
lems are new to the top 10 of least concern and one problem in the group is new to the survey.
“Exporting My Products/Services” holds onto the 75th
ranking, a position held for six of
seven editions that it has been listed as a problem. It moved up one position in 2000, replaced
by the problem “Y2K Impacts.
What can governments do to support and drive these initiatives further? The most important thing is
to provide clear and consistent environmental policies which will fix market failures and give institutional
investors the confidence to invest in green projects. Without these policies climate finance from the private
sector will not be forthcoming.
Governments need to ensure that adequate, investment-grade deals at scale come to the market in
order to be able to tap the potential pension funds cash.
For both groups we combined all the answers in which subjects gave the same confidence
assessment and calculated how often they were right. Good calibration means that the
fraction of correct answers should be about equal to the stated confidence level. For example,
on questions where subjects said they were 80 percent confident, they should be right about
80 percent of time. If subjects are well calibrated, then a graph of the percent correct against
the confidence levels should lie near a 45◦ line.
Instead, this report will describe some of the notable sources and organizers of culturally and
linguistically appropriate information locally and nationally, discuss related cultural competence
issues, and look into some possible ways to increase access to such materials through building
on existing infrastructures. The centerpiece of this project was a focus group and interviews
with professionals particularly interested in linguistic access to care, cultural competence, and
access to information.
Cybersecurity is a complex set of issues involving legal, economic, and national security
considerations. In the House, at least nine committees have some significant jurisdictional
claim on cyber issues. In May, the White House submitted its legislative language for
discussion. The Senate has attempted to construct a comprehensive cyber bill for the last two
Given the difficulties, it is reasonable to ask why the House should devote time and energy to
an issue that is not at the top of the public’s expressed priorities. ...
The therapeutic fields where stratified medicine is expected to take off first are oncology,
secondary complications of diabetes, cardiovascular diseases and neurodegenerative diseases.
Though, the development of stratified medicine is largely dependant of the identification and the
qualification of pertinent biomarkers in these areas. Regrettably, only a few studies on
biomarkers have proved to be sufficiently powered to detect differences among genetic variants
and/or the function of gene products.