Causes dementia

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  • Mutations in neuroserpin anda1-antitrypsin cause these proteins to form ordered polymers that are retained within the endoplasmic reticulum of neurones and hepatocytes, respectively. The resulting inclusions underlie the dementia familial encephalopathy with neuroserpin inclusion bodies (FENIB) and Z a1-antitrypsin-associated cirrhosis.

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  • It was November 1901, and Karl Deter of Germany did not know what to do about his wife, Auguste. Over the previous several months, her behavior had changed drastically. Only fiftyone years old, Auguste had lost the ability to remember things from one minute to the next. She had lost the ability to express herself with words. She was often confused about what day it was, where she was, and even who she was. She had frequent outbursts of anger and paranoid thinking. She would hide things, thinking her family was trying to steal from her.

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  • Presents cutting-edge information on a variety of dementia-causing illnesses. Provides relevant material for professionals working with AIDS patients, substance abusers, stroke or other vascular patients, and other individuals suffering from degenerative illness. Edited by leading experts in geriatric health and dementia.

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  • The field of movement disorders is relatively broad, encompassing disorders of increased movement, such as tremors, dystonia, and tics, to disorders characterized by a paucity of movement, such as Parkinson’s disease. Our understanding of the pathogenic mechanisms and our treatment options are expanding at a rapid pace. This expansion ranges from the medical and surgical advances in treating Parkinson’s disease to the flood of genetic abnormalities that have now been found to cause various movement disorders.

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  • Coma: a state of unconsciousness from which the patient cannot be aroused, even by powerful stimuli. Traumatic brain injuries are the most frequent cause; other causes include severe uncontrolled diabetes mellitus, liver disease, kidney disease, and neurologic conditions Dementia: a general loss of mental abilities, including impairment of memory and often impairments in speech, coordination, ability to understand sensory stimuli, and other mental faculties.

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: HIV-1 associated dementia: symptoms and causes

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  • The dementia familial encephalopathy with neuroserpin inclusion bodies (FENIB) is caused by point mutations in the neuroserpin gene.We have shown a correlation between the predicted effect of the mutation and the number of intracerebral inclusions, and an inverse relationshipwith the age of onset of disease. Our previous work has shown that the intraneuronal inclusions in FENIB result from the sequential interactionbetween the reactive centre loopofone neuroserpin molecule withb-sheet A of the next. ...

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  • Among all the clinical indications for which radiologists, nuclear medicine physicians, neurologists, neurosurgeons, psychiatrists (and others examining disorders of the brain) order and read brain PET scans, demand is greatest for those pertaining to dementia and related disorders. This demand is driven by the sheer prevalence of those conditions, coupled with the fact that the differential diagnosis for causes of cognitive impairment is wide and often difficult to distinguish clinically.

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  • Agitation (dễ cáu gắt) is an unpleasant state of extreme arousal, increased tension, and irritability anxiety (lo lắng) Fear or apprehension or dread of impending danger and accompanied by restlessness, tension, tachycardia, and dyspnea unattached to a clearly identifiable stimulus.

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  • Despite the theoretical advantages of identifying individuals with cognitive impairment, there is no evidence to indicate whether this leads to a net benefit or risk to the individual. Although pharmaceutica agents are able to produce measurable changes in cognitive performance in people with Alzheimer’s disease, none has been shown to result consistently in clinically significant improvement. The high cost of investigation to exclude reversible causes of dementia, and the negative effects of labelling are examples of potential harm.

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  • Figure 27-3 Evidence of left hemispatial neglect and simultanagnosia. A. A 47-yearold man with a large frontoparietal lesion in the right hemisphere was asked to circle all the As. Only targets on the right are circled. This is a manifestation of left hemispatial neglect. B. A 70-year-old woman with a 2-year history of degenerative dementia was able to circle most of the small targets but ignored the larger ones. This is a manifestation of simultanagnosia.Cerebrovascular lesions and neoplasms in the right hemisphere are the most common causes of hemispatial neglect.

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  • Insomnia Associated with Neurologic Disorders A variety of neurologic diseases result in sleep disruption through both indirect, nonspecific mechanisms (e.g., pain in cervical spondylosis or low back pain) or by impairment of central neural structures involved in the generation and control of sleep itself. For example, dementia from any cause has long been associated with disturbances in the timing of the sleep-wake cycle, often characterized by nocturnal wandering and an exacerbation of symptomatology at night (so-called sundowning).

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  • Nevertheless, this report provides an overview of issues related to women’s health across the EU Member States also including EEA countries. It highlights gaps and special topics where research and more information are needed.

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