Cellular and molecular

Xem 1-20 trên 133 kết quả Cellular and molecular
  • (BQ) Part 1 book "Cellular and molecular immunology" presents the following contents: Properties and overview of immune responses, cells and tissues of the immune system, leukocyte circulation and migration into tissues, innate immunity, antibodies and antigens, immune receptors and signal transduction,...

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  • (BQ) Part 2 book "Cellular and molecular immunology" presents the following contents: Differentiation and functions of CD8+ effector T cells; B cell activation and antibody production, immunologic tolerance and autoimmunity, effector mechanisms of humoral immunity, immunity to microbes, transplantation immunology,...

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  • (BQ) Part 1 book "Ganong's review of medical physiology" presents the following contents: Cellular and molecular basis for medical physiology, central and peripheral neurophysiology, endocrine and reproductive physiology.

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  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Cellular and molecular mechanisms of cigarette smoke-induced lung damage and prevention by vitamin C...

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  • (BQ) Part 1 book "Ganong's review of medical physiology" presents the following contents: Cellular and molecular basis for medical physiology, central and peripheral neurophysiology, endocrine and reproductive physiology.

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  • By 2020, a better molecular definition of “health” and “ill-health” will have been achieved and early markers that identify the transition between the two states will have been identified. This will be delivered by studying cellular and molecular mechanisms of both states and by studying the interplay between environmental factors to which the population is exposed and their genetic make-up.

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  • The mitogenic toxin fromPasteurella multocida(PMT) is a member of the dermonecrotic toxin family, which includes toxins fromBordetella, Escheri-chia coliandYersinia. Members of the dermonecrotic toxin family modu-late G-protein targets in host cells through selective deamidation and⁄or transglutamination of a critical active site Gln residue in the G-protein tar-get, which results in the activation of intrinsic GTPase activity.

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  • Over the last three decades, knowledge on the molecular biology of human cancers has vastly expanded. A host of genes and proteins involved in cancer development and progression have been defined and many mechanisms at the molecular, cellular and even tissue level have been, at least partly, elucidated. Insights have also been gained into the molecular mechanisms underlying carcinogenesis by chemical, physical, and biological agents and into inherited susceptibility to cancer. Accordingly, Part I of the book presents many of the molecules and mechanisms generally important in human cancers.

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  • A global research community of scientists is teasing out the biochemical mechanisms that regulate normal cellular physiology in a variety of organisms. Much of current research aims to understand the network of molecular reactions that regulate cellular homeostasis, and to learn what allows cells to sense stress and activate appropriate biochemical responses.

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  • PHOTOSYNTHESIS PROVIDES the organic building blocks that plants (and nearly all other life) depend on. Respiration, with its associated carbon metabolism, releases the energy stored in carbon compounds in a controlled manner for cellular use. At the same time it generates many carbon precursors for biosynthesis. In the first part of this chapter we will review respiration in its metabolic context, emphasizing the interconnections and the special features that are peculiar to plants.

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  • Within the last decade the interest in lipases has increased dramatically, and no doubt, this interest will be maintained in the future. Novel and powerful tools of molecular biology, crystallography, NMR technology and molecular modeling will continue to reveal new amino acid sequences and three-dimensional structures of lipases. In addition, transgenic and knockout animal models as well as the use of specific inhibitors will add knowledge about their mode of interaction with lipid substrates, cleavage mechanism and physiological roles in humans....

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  • RNA-mediated gene silencing (RNA interference) is a powerful way to knock down gene expression and has revolutionized the fields of cellular and molecular biology. Indeed, the transfection of cultured cells with small interfering RNAs (siRNAs) is currently considered to be the best and easi-est approach to loss-of-function experiments.

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  • In 1895, Roux set out the problems confronting the new subject of experimental embryology and commented that, although he and his peers intended to simplify what was clearly a very complicated set of events, they knew so little about development that they would be unable to elucidate the underlying mechanisms without a great deal of work. Moreover, because they were so ignorant, they could not know which approaches would be the most helpful in their attempts to gain understanding.

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  • Human dynein light chain 1 (DYNLL1) is a dimeric 89-residue protein that is known to be involved in cargo binding within the dynein multiprotein complex. Over 20 protein targets, of both cellular and viral origin, have been shown to interact with DYNLL1, and some of them are transported in a retrograde manner along microtubules.

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  • Uterine myomas are the most common benign tumors in women, affecting 20%–50% of reproductive age population. Myomas cause significant morbidity and are the single most common indication for hysterectomy in the United States, representing a major personal and public health concern worldwide. Recent research on the cellular and molecular biology of myomas has enabled us to understand better the pathogenesis and pathophysiology of this tumor, but more remains to be done.

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Department of Molecular, Cellular, and Developmental Biology...

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  • "Molecular imaging" has been previously defined as "the in vivo characterization and measurement of biologic processes at the cellular and molecular level." This broad definition emerged during the last few years as a consequence of the convergence of molecular and cell biology with imaging science, including medical physics and technology. One of the major goals of molecular imaging has become the development of noninvasive strategies of "molecular profiling" in living subjects, i.e.

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  • In the treatment of bone pain, the second step on the WHO analgesic ladder is commonly unhelpful, with inadequate pain relief or the development of undesirable/intolerable side-effects (Eisenberg, 2005). There is currently no place for interventional treatment on the ladder and the earlier recommendations of a fourth step of interventional management are not applied widely enough. The main principles of pain management, including the use of a biopsychosocial approach, should be applied, rather than simply following the WHO ladder.

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  • Cancer may constitute the most extensively studied disease entity of our time. Nevertheless, our comprehension of the cellular and molecular pathology of malignant transformation is incomplete. In view of the diverse clinical presentations of various malignancies, doubts may be raised as to whether it is appropriate to refer to cancer as one group of disease states. The notion of malignant tumors as a pathologic and pathophysiologic class of conditions begs the question for defining criteria that characterize all malignant growths, regardless of their tissue of origin....

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  • The public demand for the protection of human and environmental health has led to the establishment of toxicology as the science of the action of chemicals on biological systems. Toxicological research is focused presently very much on the elucidation of the cellular and molecular mechanisms of toxicity and the application of this knowledge in safety evaluation and risk assessment.

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