Cellular immunology

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  • In this 3rd edition of Anatomy, Histology, and Cell Biology: PreTest Self-Assessment and Review, a significant number of changes and improvements have been made. This PreTest reviews all of the anatomical disciplines encompassing early embryology, cell biology, histology of the tissues and organs, as well as regional human anatomy of the head and neck, thorax, abdomen, pelvis, extremities, and spine. This edition represents a comprehensive effort to integrate the anatomical disciplines with clinical scenarios and cases.

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  • The currently available treatment options for glomerular disorders are not optimal since most of them either respond only partially or poorly so that relapse and progression is often the rule. Inadequate understanding of the factors underlying the development and progression of glomerular injury in various clinical scenarios is primarily responsible for lack of ideal therapies. The section on immune system and glomerulonephritis has three chapters which basically cover some of the actively investigated areas. Tetsuhiro Tanaka et al.

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  • Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA. †Department of Microbiology, Molecular Genetics, and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA. Correspondence: Galina V Glazko. E-mail: gvg@stowers-institute.org reviews Published: 27 April 2004 Genome Biology 2004, 5:R32 The electronic version of this article is the complete one and can be found online at http://genomebiology.com/2004/5/5/R32

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  • In the treatment of bone pain, the second step on the WHO analgesic ladder is commonly unhelpful, with inadequate pain relief or the development of undesirable/intolerable side-effects (Eisenberg, 2005). There is currently no place for interventional treatment on the ladder and the earlier recommendations of a fourth step of interventional management are not applied widely enough. The main principles of pain management, including the use of a biopsychosocial approach, should be applied, rather than simply following the WHO ladder.

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  • Retrovirology Research BioMed Central Open Access HIV-1 TAR miRNA protects against apoptosis by altering cellular gene expression Zachary Klase1, Rafael Winograd1, Jeremiah Davis1, Lawrence Carpio1, Richard Hildreth1, Mohammad Heydarian2, Sidney Fu2, Timothy McCaffrey2, Eti Meiri3, Mila Ayash-Rashkovsky3, Shlomit Gilad3, Zwi Bentwich3 and Fatah Kashanchi*1 Address: 1The Department of Microbiology, Immunology and Tropical Medicine program, The George Washington University School of Medicine, Washington, District of Columbia 20037, USA, 2The Department of Biochemistry and Molecular Biology...

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  • Signal peptide peptidase (SPP) is an aspartic proteinase that hydrolyses its substrate within the plane of the cellular membrane. In vertebrates, it plays crucial roles in life processes such as differentiation, embryogenesis, cell signaling and immunological response. We first found SPP in plants. An ortholog of human SPP (AtSPP), and its five AtSPP homologs (AtSPPL1– AtSPPL5), were searched for in theArabidopsisdatabase.

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