Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Pharmacological treatment of delayed cerebral ischemia and vasospasm in subarachnoid hemorrhage
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Lack of association between right-to-left shunt and cerebral ischemia after adjustment for gender and age
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Bench-to-bedside review: A possible resolution of the glucose paradox of cerebral ischemia...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Anti-inflammatory effects of Chinese medicinal herbs on cerebral ischemia...
Both hypoxia and hyperoxia, deregulating the oxidative balance, may play a role in the pathology of neurodegenerative disorders underlain by cerebral ischemia. In the present study, quantitative proton magnetic resonance spectroscopy was used to evaluate regional metabolic alterations, following a 24-hour hypoxic or hyperoxic exposure on the background of ischemic brain insult, in two
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Inhibition of NF-κB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Argon: Neuroprotection in in vitro models of cerebral ischemia and traumatic brain injury...
Tendons are known to have a profound impact on the overall function of the
musculoskeletal system in their role as a structural link and force transmitter between
muscle and bone. Their unique viscoelastic response under tension allows efficient use and
recycling of stored energy during stretch involved in locomotion, modulating joint position
control, and providing protection from muscle injuries through reduction of mechanical
oscillation and shock.
Molecular cloning has identified eight metabotropic glutamate receptor (mGluR)
subtypes, each with distinct patterns of expression. However, the characteristic roles of
these different mGluRs in physiological processes are not well understood.
Identification of subtype-specific compounds may potentially act as therapeutic agents
for the treatment of a wide range of conditions (including progressive brain disease,
epilepsy and cerebral ischemia) all of which are associated with abnormal mGLuR
Harrison's Internal Medicine Chapter 21. Syncope
Syncope, a transient loss of consciousness and postural tone due to reduced cerebral blood flow, is associated with spontaneous recovery. It may occur suddenly, without warning, or may be preceded by symptoms of faintness ("presyncope"). These symptoms include lightheadedness, dizziness, a feeling of warmth, diaphoresis, nausea, and visual blurring occasionally proceeding to transient blindness.
As it is
associated with significant number of complications (11,8% to 21,6%) as well as high
costs, some authors advocate conservative treatment. High incidence of re-ruptures
(12% to 17%), lengthened tendon and loss of strength are the main arguments for the
opponents to criticize this method. Percutaneous repair seems to bridge the gap,
combining the advantages of conservative and operative treatment, particularly if
performed in an outpatient manner and under local anesthesia.
Presyncopal symptoms vary in duration and may increase in severity until loss of consciousness occurs, or they may resolve prior to loss of consciousness if the cerebral ischemia is corrected. The differentiation of syncope from seizure is an important, sometimes difficult, diagnostic problem.Syncope may be benign when it occurs as a result of normal cardiovascular reflex effects on heart rate and vascular tone, or serious when due to a life-threatening cardiac arrhythmia.
As the rupture most commonly occurs in “mid-aged” persons (in the most creative
and productive part of life), the highest effort should be put in enabling patients to
return to previous activities as soon as possible. There is universal agreement that
functional treatment is the most effective way in this regardless of the used
conservative or operative (open or percutaneous) method.
Stroke involves cerebral infarction and hemorrhaging and is associated with very high
mortality. Previous reports have indicated that ischemic stimulation such as the
reoxygenation that occurs after hypoxia produces a large quantity of reactive oxygen species
(ROS) that strongly induces neuronal death in vivo and in vitro (Negishi et al., 2001). Indeed,
this is considered to be the factor that most strongly induces cell death in cerebral ischemia.
In recent years, apoptosis has been suggested to be the mechanism responsible for ischemic
neuronal death in animal stroke models (Tagami et al.
Cerebral ischemia triggers robust phosphorylation of cAMP response ele-ment-binding protein (CREB) and CRE-mediated gene expression in neu-rons. Glutamate receptor activation and subsequent calcium influx may
activate CREB shortly after ischemia.
The extracellular signal regulated protein kinases (ERK1/2)
are essential for normal development and functional plasti-city of the central nervous system. However, a growing
number of recent studies in models of cerebral ischemia,
brain trauma and neurodegenerative diseases implicate a
detrimental role for ERK1/2 signaling during oxidative
neuronal injury. Neurons undergoing oxidative stress-rela-ted injuries typically display a biphasic or sustained pattern
of ERK1/2 activation.
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Protective effects and potential mechanisms of Pien Tze Huang on cerebral chronic ischemia and hypertensive stroke...
MicroRNAs are small RNAs that attenuate protein expression by comple-mentary binding to the 3¢-UTR of a target mRNA. Currently, very little
is known about microRNAs after cerebral ischemia. In particular, micro-RNA-21 (miR-21) is a strong antiapoptotic factor in some biological
systems. We investigated the role of miR-21 after stroke in the rat.
An emerging body of evidence supports a key role for the endocannabinoid
system in numerous physiological and pathological mechanisms of the cen-tral nervous system. In the recent past, many experimental studies have
examined the putative protective or toxic effects of drugs interacting with
cannabinoid receptors or have measured the brain levels of endocannabi-noids inin vitro and in vivo models of cerebral ischemia.
Endogenous levels of the endocannabinoid anandamide, and the activities
of the synthesizing and hydrolyzing enzymes, i.e.N-acylphosphatidyletha-nolamine-hydrolyzing phospholipase D and fatty acid amide hydrolase,
respectively, were determined in the cortex and the striatum of rats sub-jected to transient middle cerebral artery occlusion.