In its fifth edition, Cancer Medicine has been named eponymously to honor its founding
editors James F. Holland and Emil Frei III, two giants of medical oncology. The Holland-Frei
Cancer Medicine reflects their dedication to innovative, comprehensive, and multidisciplinary
care of cancer patients, as well as their belief in the importance of grounding such care in a more
fundamental understanding of cancer biology. It is to their vision and the example that they have
established over the last four decades that this book is dedicated.
Hình ảnh và mức độ của thương tổn nghịch sản
- Nghịch sản nhẹ: bề dày của liên bào có thể tăng hoặc không nhưng các tế bào ở 1/3 dưới có rối loạn về cấu trúc - Nghịch sản trung bình: số tế bào bất thường chiếm 2/3 bề dày của liên bào * Năm 1970 Richart đưa ra thuật ngữ mới CIN (Cervical Intraepithelial Neoplasia) – khối tân sản nội liên bào và chia làm CIN I, CIN II, CIN III tương ứng với loạn sản nhẹ, loạn sản vừa và loạn sản nặng.
* Năm 1988 các nhà...
If a patient has previously undergone a hysterectomy, the cervix is usually
no longer present and only a vaginal cuff remains. If the pathology was
benign, then the patient no longer requires Pap smears (11). However, if the
hysterectomy was performed for cervical cancer or dysplasia, cervical cancer
screening on the vaginal cuff should continue since remnants of cervical
tissue may be present. These women are also at higher risk for vaginal in-
traepithelial neoplasia (VAIN) and vaginal cancer.
Exfoliative cytologic examination of specimens from the lower genital tract (Pap smear) is a screening tool that has been so valuable in the detection of premalignant and malignant lesions that it has been almost universally adopted as the primary cancer screening method for cervical cancer, an integral part of the health care of women. This has resulted in a 50% reduction of invasive cancers of the cervix alone. Although cervical cytology may detect endometrial cancer (in 15%–50%), it does not carry the same reliability as a screening tool for endometrial neoplasia.
A recent report
from mainland China concluded that
HPV DNA testing is highly sensitive and moderately
specific for cervical intraepithelial neoplasia 3 or worse
(CIN3+; CIN3 is the usual immediate precursor to
invasive cervical cancer), with consistent results across
study sites and age groups. This paper reviewed reports
of more than 30,000 women from population-based
screening studies done between 1999 and 2008, with
the aim of assessing whether HPV DNA testing could be
applied to cervical cancer screening programs in China.