Chromosome segregation in meiosis. A. In meiosis I, each of the 23 pairs of chromosomes finds its "partner," or homologue, and exchanges genetic material (recombines) with it. At metaphase, each homologous pair aligns on the equatorial plate; at anaphase, each member of the homologous pair segregates from its partner. Thus, at the end of meiosis I, each daughter cell contains 23 chromosomes, with each chromosome consisting of two sister chromatids. B. In meiosis II, each chromosome aligns on the metaphase plate, and at anaphase, each of the two sister chromatids divides from the other.