Eugene “Bill” Wilson (1900–1981) was Dean of Admission at
Amherst College. He was known for his sense of humor and his genuine
interest in the welfare of each student. This quote attributed to him,
published in Reader’s Digest in April of 1968, summarizes education to
me, that is, it is learning itself that is most exciting, not the knowledge
per se that one gathers from it. It is truly the lifelong ride of learning, not
the final destination, that makes us what we are.
Our goal in creating the
Dermatology: Clinical & Basic Science Series
is to present
the insights of experts on emerging applied and experimental techniques and theoretical
concepts that are, or will be, at the vanguard of dermatology. These books
cover new and exciting multidisciplinary areas of cutaneous research, and we want
them to be the books every physician will use to become acquainted with new
methodologies in skin research. These books can be also given to graduate students
and postdoctoral fellows when they are looking for guidance to start a new line of
The nonmedical use of drugs presents social problems with important pharmacological aspects. Social aspects Rewards for the individual Decriminalisation and legalisation Dependence Drugs and sport Tobacco Dependence Nicotine pharmacology Effects of chronic smoking Starting and stopping use Passive smoking Ethyl alcohol Pharmacology Car driving and alcohol Chronic consumption Withdrawal Pregnancy Pharmacological deterrence Psychodysleptics • Experiences with psychodysleptics • Individual substances, especially cannabis Stimulants • cocaine, • amfetamines.
tive driving skills and other tasks requiring precise sensorimotor coordination will be impaired. Triazolam (t1/2 of elimination ~1.5–5.5 h) is especially likely to impair memory (anterograde amnesia) and to cause rebound anxiety or insomnia and daytime confusion. The severity of these and other adverse reactions (e.g., rage, violent hostility, hallucinations), and their increased frequency in the elderly, has led to curtailed or suspended use of triazolam in some countries (UK).
The sequencing of the human genome has generated excitement about
the potential of genomic innovations to improve medical care, preventive and
community health services, and public health. Until fairly recently, genetic
information was used primarily in the diagnosis of relatively rare genetic diseases,
such as cystic fibrosis and Huntington’s Disease, but a transformation
in the use of genetic and genomic information is under way.
Genetic markers of increased risk for such chronic diseases as diabetes
and coronary artery disease have been identified.