Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: The potential of human regulatory T cells generated ex vivo as a treatment for lupus and other chronic inflammatory diseases...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Altered lipoprotein metabolism in chronic inflammatory states: proinflammatory high-density lipoprotein and accelerated atherosclerosis in systemic lupus erythematosus and rheumatoid arthritis...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: The Changing Microbial Environment and Chronic Inflammatory Disorders...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Direct Toll-like receptor 2 mediated co-stimulation of T cells in the mouse system as a basis for chronic inflammatory joint disease...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Cost-utility of Intravenous Immunoglobulin (IVIG) compared with corticosteroids for the treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Canada...
Rheumatoid arthritis (RA) is a chronic, systemic inflammatory
disease primarily of the joints that, if lelt untreated, results in functional
disebility concordant with radiographic progression. It is well recognized
that strking pathogenic similarities exist between periodontitis and RA.
Proinflammatory cytokines such as tumor necrosis factoralpha (TNF a) and
interleukin (IL) as well as microbial enzymes and host matrix
metalloproteianses (MMP-8 and -9) appear to play important roles in both
In this book dealing with the lung health, the authors focus on various fields, spreading from pulmonary oncogenesis, to inflammatory and parasitic lung diseases. The first section deals with the fundamental research on lung cancer that is mandatory for the development of novel and early biomarkers for diagnosis of the lung cancer. This development could be enhanced using experimental models despite the species barrier. Mouse models can help us understand the sequence of events involved in human lung neoplasia and their underlying molecular mechanisms....
Periodontal disease is one of the major dental pathologies that affect human populations
worldwide at high prevalence rates (Petersen, 2003). Periodontal diseases represents a
family of heterogeneous chronic inflammatory lesions that involve the periodontium, a
connective tissue protected by the epithelium, important to attach the teeth to the bone in
the jaws and to support the teeth during function (Taylor, 2003).
Gingivitis and periodontitis are the two main periodontal diseases and may be present
concurrently. Gingivitis is a form of periodontal disease in which gingival tissues are
inflamed but their destruction is mild and reversible while periodontitis is a chronic
inflammatory response to the subgingival bacteria with irreversible changes (Armitage,
1999). Periodontium destruction is characterized by loss of connective tissue attachment and
bone around the teeth in conjunction with the formation of periodontal pockets due to
apical migration of the junctional epithelium (Champagne et al.
The pathogenesis of osteomyelitis is a complex process involving interactions between a
host and an infectious agent. The host’s inflammatory response to a pathogen can further
the physical spread of disease by clearing space in bone. Predisposing genetic differences in
immune function are increasingly seen as an aetiological factor in some cases of
osteomyelitis. Acquired factors such as diseases causing immune or vascular compromise
and implantation of foreign materials are frequently involved in the disease process as well. ...
The putative CLL precursor could be an antigen-experienced CD27+ B cell, expanded either
in the course of a GC B-cell T-dependent or T-independent response by chronic antigen-
stimulation through extrinsic or autoantigens. Over time, genetic abnormalities may
accumulate in the genome of these chronically stimulated B cells and lead to the outgrow of
clones with MBL phenotype. Additional genetic aberrations may be incorporated in the
course of proliferation leading to the oncogenic hit that transform these precursor in bona
fide CLL cells. ...
Psoriasis (Table 53-2) Psoriasis is one of the most common dermatologic diseases, affecting up to 1% of the world's population. It is a chronic inflammatory skin disorder clinically characterized by erythematous, sharply demarcated papules and rounded plaques, covered by silvery micaceous scale. The skin lesions of psoriasis are variably pruritic. Traumatized areas often develop lesions of psoriasis (Koebner or isomorphic phenomenon). Additionally, other external factors may exacerbate psoriasis including infections, stress, and medications (lithium, beta blockers, and antimalarials).
FDA cho phép dùng thuốc mới Remicade (infliximab) cho việc điều trị bệnh viêm ruột Crohn’s disease. Remicade là một loại thuốc do điều chế kháng thể đơn dòng (monoclonal antibody). Thuốc giảm hiện tượng viêm bằng cách ngăn chặn yếu tố tumor necrosis factor-alpha (TNF-alpha). FDA Approves Remicade for Children with Crohn’s Disease The Food and Drug Administration today approved Remicade (infliximab) to treat children with active Crohn's disease, a chronic, inflammatory condition of the bowel that can be severely debilitating.
Silvola et al. EJNMMI Research 2011, 1:14 http://www.ejnmmires.com/content/1/1/14
Uptake of 68gallium in atherosclerotic plaques in LDLR-/-ApoB100/100 mice
Johanna MU Silvola1*, Iina Laitinen2, Henri J Sipilä1, V Jukka O Laine3, Pia Leppänen4, Seppo Ylä-Herttuala4, Juhani Knuuti1 and Anne Roivainen1,5
Background: Atherosclerosis is a chronic inflammatory disease of artery wall characterized by infiltration of monocytes into subendothelial space and their differentiation into macrophages.
The Janus kinase–signal transducer and activator of transcription (JAK–STAT) pathway is
utilized by a range of cytokines (interferons, IL-2 and IL-6 amongst others) that control
survival, proliferation and differentiation responses in diverse cell types. The realisation that
unregulated activation of this pathway is a key driver of not only chronic inflammatory
diseases such as rheumatoid arthritis, colitis and psoriasis, but also many cancers has
identified its components as targets for therapeutic intervention by small molecule
inhibitors and biologicals.
In the 16th century, Leonardo da Vinci had described “The narrowing of the passage of
blood vessels, thickening of the coats of these vessels and hardening of arteries”. This is the
first documentation of atherosclerosis, but today our understanding of atherogenesis as a
process of a chronic inflammatory disease has been updated by many mechanisms such as
hypercholesterolemia, dysfunction of endothelial cells, oxidation of lipoproteins and espe‐
cially oxidative stress. In particular, the endothelium is responsible for the...
Occasional injuries are part of the human experience, and healing is the
body’s self-repair process. Healing begins with inflammation, which
nature uses to clean up damaged tissues and protect against infection.
So if inflammation is beneficial, why are so many modern diseases
characterized by chronic and unhealthy inflammation?
This revised edition of The Inflammation Syndrome answers a major
part of this important question.
Physiologic Characteristics of Hypometabolic and Hypermetabolic States The metabolic characteristics and nutritional needs of hypermetabolic patients who are stressed from injury, infection, or chronic inflammatory illness differ from those of hypometabolic patients who are unstressed but chronically starved. In both cases, nutritional support is important, but misjudgments in selecting the appropriate approach may have disastrous consequences.
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Chronic nonbacterial osteomyelitis in childhood: prospective follow-up during the first year of anti-inflammatory treatment...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Active immunization to tumor necrosis factor-α is effective in treating chronic established inflammatory disease: a long-term study in a transgenic model of arthritis...