Coating process

Xem 1-20 trên 51 kết quả Coating process
  • The coating process Graham C.Cole SUMMARY In recent years tablet coating has undergone several fundamental changes. The original sugar-coating technique has been largely replaced by film-coating processes using organic solvents. The organic solvents are now being replaced by water because of the development of suitable polymers, improvements in the coating process, and legislation regulating the discharge of pollutants into the environment.

    pdf43p bigbaby87 01-09-2010 61 16   Download

  • Environmental considerations: treatment of exhaust gases from film-coating processes Graham C.Cole SUMMARY Solvents such as acetone, methylene chloride, chloroform, ethanol and methanol must be prevented from entering the environment. Two options are available: convert all the processes to aqueous-based formulations or recover all the solvent by the use of an appropriate system. Recovery is expensive and is generally the reason for pharmaceutical companies to convert coating formulations to aqueous systems or formulate aqueous coating for all new products.

    pdf9p bigbaby87 01-09-2010 56 12   Download

  • Automation of coating processes Graham C.Cole SUMMARY Current Good Manufacturing Practice (cGMP) and the demands of the regulatory authorities worldwide requires greater care in the design of manufacturing facilities, the selection of materials used in their construction, their layout, the equipment used in the preparation of tablets to be coated and the coating operation. It is claimed that robotic systems will eventually take over all processing tasks! (Kanig & Rudic, 1986).

    pdf18p bigbaby87 01-09-2010 64 12   Download

  • Validation of tablet coating processes Graham C.Cole SUMMARY Validation is a concept that means different things to different people. This chapter will highlight all the activities that are necessary to ensure that all aspects of the coating process are fully documented from design through to operation, to provide compliance with regulatory requirements. ‘If it hasn’t been documented, it hasn’t been done.’ FDA 11.

    pdf25p bigbaby87 01-09-2010 64 11   Download

  • The development of film-coating processes Graham C.Cole SUMMARY To develop a film-coating process requires a laboratory test rig that can be scaled-up to meet production requirements. All the process parameters need to be optimized. A scheme is discussed here that provides an integrated computer-controlled system designed for aqueous film coating in a side-vented pan. A comparison is made of energy requirements of a column-coating system and a coating pan. All the major operational coating parameters can be measured and recorded under the overall control of a microcomputer.

    pdf21p bigbaby87 01-09-2010 45 9   Download

  • Solution properties and atomization in film coating Michael E.Aulton and Andrew M.Twitchell SUMMARY A little-considered stage of the film-coating process is the atomization of the coating solution by the spray gun. This chapter will show how formulation and process factors can cause marked changes in the characteristics of the spray, which may have important consequences for film formation and film properties.

    pdf55p bigbaby87 01-09-2010 67 20   Download

  • Coating pans and coating columns Graham C.Cole SUMMARY This chapter provides some examples of the type of equipment that is currently available. It is not exhaustive, but will highlight the main features that should be considered when evaluating and selecting appropriate units together with ancillary equipment for spraying and control of the coating process. 8.1 CONVENTIONAL COATING PANS It is not proposed to discuss in detail the use of conventional coating pans as these are being phased out with the preference for more sophisticated pans and systems.

    pdf35p bigbaby87 01-09-2010 66 11   Download

  • This chapter contains a comprehensive listing of research papers, reviews, book chapters and theses covering the subject of pharmaceutical film coating. Coating is a very extensive subject and so this bibliography is restricted to those publications of direct pharmaceutical relevance or authorship. Nonpharmaceutical polymer science or coating processes of other industries are not included. While the listing is extensive, it is by no means exhaustive. Indeed, the author would welcome notification of any missing articles in order that this work can be included in the next edition.

    pdf19p bigbaby87 01-09-2010 121 9   Download

  • The present text introduces the use of fluidised bed processing in the context of wet granulation and coating. The text also covers introductory information about the mechanical properties of dry granules. This is a scientific field rarely taught at universities or engineering schools around the world although it has enormous and ever increasing relevance to the chemical and biochemical industries. Often students are left with nothing but qualitative tendencies and hands-on experience as no textbook yet covers all relevant subjects treated in this text....

    pdf80p tuanloc_do 04-12-2012 28 4   Download

  • Steels are alloys of iron with generally less than 1% carbon plus a wide range of other elements. Some of these elements are added deliberately to impart special properties and others are impurities not completely removed (sometimes deliberately) during the steel making process. Elements may be present in solid solution or combined as intermetallic compounds with iron, carbon or other elements. Some elements, namely carbon, nitrogen, boron and hydrogen, form interstitial solutions with iron whereas others such as manganese and silicon form substitutional solutions. Beyond......

    pdf69p quangdat 15-03-2009 859 130   Download

  • This would appear to be a very good reason for painting anything (film coating is a painting process) and while the penalty for coating tablets the wrong colour is unlikely to be so extreme, the Queen (FDA, MCA, etc.) is likely to extract very costly and damaging retribution. No doubt ‘heads would roll’ metaphorically. So why are tablets coated? After all, it is a messy, complicated and expensive process.

    pdf22p bigbaby87 01-09-2010 98 35   Download

  • The chapter commences by reviewing the properties of the broad classes of materials used in film coating, polymers, plasticizers, pigments and solvents (or vehicles). An initial consideration of the polymers shows that while processing is most commonly performed using these materials in solution, there are systems which utilize polymers in suspension in water. The mechanism of coalescence and film formation for these types of materials are discussed.

    pdf50p bigbaby87 01-09-2010 93 32   Download

  • Surface effects in film coating Michael E.Aulton SUMMARY This chapter will explain the significance of the stages of impingement, wetting, spreading and penetration of atomized droplets at the surface of tablet or multiparticulate cores. It will explain some of the fundamental aspects of solid-liquid interfaces which are important to the process of film coating. This chapter will emphasize the importance of controlling the ‘wetting power’ of the spray and the ‘wettability’ of the substrate, and will explain how this can be achieved by changes in formulation and process parameters.

    pdf33p bigbaby87 01-09-2010 62 14   Download

  • Covers all basic aspects of the chemistry of resins and binders, their solubility in solvents, and their compatibility with pigments essential for modern coating material. Presents state-ofthe-art knowledge of organic coatings materials and their manufacturing and processing. DLC: Gums and resins.

    pdf423p kennybibo 14-07-2012 56 13   Download

  • Some common practical questions and suggested answers During the development of coating formulae and processes, common problems tend to recur. This section brings together a collection of typical queries and provides suggested solutions. 1. Question: What major process and formulation parameters do I need to take into account in the change from organic solvent coating to aqueous coating? Answer: Looking first of all at the formulation-based parameters, there is a need to increase the solids loading of the coating suspension to something like 12 %w/w if using a typical HPMC-based formula.

    pdf8p bigbaby87 01-09-2010 67 8   Download

  • Dieter Stoye, Werner Freitag (Editors) Covers all basic aspects of the chemistry of resins and binders, their solubility in solvents, and their compatibility with pigments essential for modern coating material. Presents state-ofthe-art knowledge of organic coatings materials and their manufacturing and processing. DLC: Gums and resins. This hook was carefully

    pdf423p chipmoon 19-07-2012 37 8   Download

  • In the discussion above, high surface tension and low viscosity are required for good flow-out and leveling. But high surface tension can cause cratering, and excessively low viscosity would result in sagging and poor edge coverage. To obtain an optimal coating, the balance between surface tension and viscosity is important. Figure 2.12 illustrates coating performance as a function of surface tension and melt viscosity. Coating is a fairly complex process; achieving an optimal result calls for the consideration of many factors....

    pdf10p lyacau 30-12-2009 84 37   Download

  • Every day countless kilometres of steel pipelines are installed worldwide for the most varied civil and industrial uses. They form real networks comparable to a system of road networks, which, although not so obvious, are definitely much more intricate and carry fluids that have become essential for us. To comply with technical specifications and fulfil the necessary safety requisites, special materials and welding processes which have evolved with the sector have been developed in recent years.

    pdf63p maythuykhi 13-12-2012 85 31   Download

  • A basic understanding of rheology and surface chemistry, two primary sciences of liquid flow and solid–liquid interaction, is necessary for understanding coating and printing processes and materials. A generally qualitative treatment of these subjects will suffice to provide the insight needed to use and apply coatings and inks and to help solve the problems associated with their use.

    pdf30p hiruscar 13-10-2010 81 26   Download

  • A basic understanding of rheology and surface chemistry, two primary sciences of liquid flow and solid–liquid interaction, is necessary for understanding coating and printing processes and materials. A generally qualitative treatment of these subjects will suffice to provide the insight needed to use and apply coatings and inks and to help solve the problems associated with their use.

    pdf40p lyacau 30-12-2009 79 23   Download

CHỦ ĐỀ BẠN MUỐN TÌM

Đồng bộ tài khoản