In a Global scenario, economically progressive nations have developed medical
sciences. But still it lacks precise information during the enhancement of potent drugs
to combat ailment, which is the legacy of the organisms that generate diseases. Rising
countries had long been perceived the threat, which at times, down the lane has been
the major factor for magnanimous economic disaster and human poverty. Lot of
resources was put into force by the world community to abscond the microbial fauna
and genetically inherited diseases to contain them within the safe limits.
Given the enormous number of microorganisms ingested with every meal, the normal host must combat a constant influx of potential enteric pathogens. Studies of infections in patients with alterations in defense mechanisms have led to a greater understanding of the variety of ways in which the normal host can protect itself against disease.
The large numbers of bacteria that normally inhabit the intestine act as an important host defense by preventing colonization by potential enteric pathogens.
The United States is pursuing a comprehensive, whole-of-government approach to global health through the Global
Health Initiative (GHI). GHI seeks to achieve significant health improvements and foster sustainable effective, efficient
and country-led public health programs that deliver essential health care. Through GHI the Obama Administration
is committed to improving and saving lives by strengthening health systems.
Can we build a safe, self-driving vehicle? Yes. In fact, Google has already logged more
than 200,000 miles in a fleet of self-driving cars retrofitted with sensors. And Google
is not alone; traditional automakers and suppliers have also developed self-driving
functionality using sensor-based solutions and have a host of new applications in
We live in a world heavily populated by microorganisms of astonishing diversity. Most of these exist in our external environment but certain classes are normally harboured within our bodies, especially colonising mucosal surfaces. Depending on the circumstances, infectious disease can arise from organisms living exogenously or endogenously, and a knowledge of common pathogens at specific sites often provides a good basis for rational initial therapy.
Many mycobacterial species, including M. tuberculosis, grow extremely slowly in the
laboratory and require 3–8 weeks of incubation on solid medium or at least 2 weeks in a
radiometric liquid culture system (BACTEC). This slow growth often leads to delay in TB
diagnosis. Nucleic acid amplification (NAA) methods allow for detection of mycobacterial
DNA or RNA directly from the specimens before the culture results are available. The Food
and Drug Administration (FDA) has approved two NAA tests for direct detection of M.
tuberculosis from clinical specimens.
2004Tuberculosis is a major health problem throughout the world causing large number of deaths,more than that from any other single infectious disease. The review attempts to summarize theinformation available on host immune response to Mycobacterium tuberculosis. Since the mainroute of entry of the causative agent is the respiratory route, alveolar macrophages are theimportant cell types, which combat the pathogen. Various aspects of macrophage-mycobacteriuminteractions and the role of macrophage in host response such as binding of M.