Nurse educators always have a dual role—they are both nurses and educators. As nurses
they often have a specialty, such as psychiatric nursing or nephrology nursing, and they
need to keep up with developments in that specialty, both in terms of the literature and
the practice. When such nurses become educators, they also have to master the field of
education, and keep up with what is new in the field of education, both in terms of theory
When we began working in pediatric neurosurgery as advanced practice
nurses, we searched for a reference that would explain the different neurosurgical
conditions affecting our patients and teach us how to care for
them. There was nothing to be found. We asked our colleagues for a reference
and they, too, had found none. “Someone should write a book about
how to care for pediatric neurosurgery patients,” we all said each time we
met at the AANS pediatric neurosurgery section meeting.
Finally, it dawned on us. We were the someone.
Transfusion of granulocytes has no role in the management of febrile neutropenia, owing to their exceedingly short half-life, mechanical fragility, and clinical syndromes of pulmonary compromise with leukostasis after their use. Instead, colony-stimulating factors (CSFs) are used to augment bone marrow production of PMNs.
GM-CSF is one of several naturally occurring glycoproteins
that regulate leukocyte production, migration and function.
It has been produced in different cell types, with different
properties that depend on the production process used. The
purpose of this work was to characterize the recombinant
human GM-CSF from an engineered Chinese hamster
ovary cell line grown in suspension and as adherent culture
for the identification of the glycosylation sites and the defi-nition of the glycosidic moiety, including the degree of site