Xem 1-20 trên 35 kết quả Derived formats
  • Masaki Okumura1,2, Masatoshi Saiki2,3, Hiroshi Yamaguchi1 and Yuji Hidaka2 1 School of Science and Technology, Kwansei Gakuin University, Hyogo, Japan 2 Graduate School of Science and Engineering, Kinki University, Osaka, Japan 3 Department of Applied Chemistry, Faculty of Engineering, Tokyo University of Science, Yamaguchi, Japan Keywords arginine; disulfide; folding; glutathione; uroguanylin Correspondence Y.

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  • This paper proposes the application of finite-state approximation techniques on a unification-based grammar of word formation for a language like German. A refinement of an RTN-based approximation algorithm is proposed, which extends the state space of the automaton by selectively adding distinctions based on the parsing history at the point of entering a context-free rule. The selection of history items exploits the specific linguistic nature of word formation.

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  • The existence of words is usually taken for granted by the speakers of a language. To speak and understand a language means - among many other things - knowing the words of that language. The average speaker knows thousands of words, and new words enter our minds and our language on a daily basis.

    pdf264p phongvan_du 01-01-2010 1361 668   Download

  • Daniel Jones (1881-1967) played a significant role in the emergence of phonetics as a fully developed academic discipline in the first half of the twentieth century. Jones's pioneering works are made easily accessible to scholars once again.

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  • The historical background of probiotics can be traced back to when the first definition of probiotic bacteria was given by Russian scientist Elie Metchnikoff who stated that probiotics are considered to exert a beneficial effect on the host. This was confirmed later on by an official statement by FAO/WHO. In their reviews, two group of investigators Matur et al. and Boaventura et al., presented the impact of probiotics on the physiology of the GIT and the underlying mechanism of action of this microflora and the benefits derived with the use of probiotics in human and animal nutrition.

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  • Weblogs and message boards provide online forums for discussion that record the voice of the public. Woven into this mass of discussion is a wide range of opinion and commentary about consumer products. This presents an opportunity for companies to understand and respond to the consumer by analyzing this unsolicited feedback. Given the volume, format and content of the data, the appropriate approach to understand this data is to use large-scale web and text data mining technologies.

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  • Pigment epithelium-derived factor (PEDF), a potent blocker of angiogene-sis in vivo, and of endothelial cell migration and tubule formation, binds with high affinity to an as yet unknown protein on the surfaces of endothe-lial cells. Given that protein fingerprinting suggested a match of a 60 kDa PEDF-binding protein in bovine retina withBos taurusF1-ATP synthase b-subunit, and that F1Fo-ATP synthase components have been identified recently as cell-surface receptors, we examined the direct binding of PEDF to F1. ...

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  • The culture framework helps us to understand culturally diverse project stakeholders better. Yet, they are not tailored to the context of project management. Kathrin Köster have selected the most relevant culture dimensions with regard to project management and summarized them in the so-called cultural gap tool. Those are dimensions derived from business practice. Being bi-polar, the culture gap tool also simplifies cultures and is not suited to describe and analyses the behavior of a single stakeholder.

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  • Nonenzymatic covalent binding (glycation) of reactive aldehydes (from glu-cose or metabolic processes) to low-density lipoproteins has been previ-ously shown to result in lipid accumulation in a murine macrophage cell line. The formation of such lipid-laden cells is a hallmark of atheroscler-osis.

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  • Plumbago indicaL. contains naphthoquinones that are derived from six acetate units. To characterize the enzyme catalyzing the first step in the biosynthesis of these metabolites, a cDNA encoding a type III polyketide synthase (PKS) was isolated from roots of P. indica. The translated poly-peptide shared 47–60% identical residues with PKSs from other plant spe-cies.

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  • The effect of the extracellular chaperone, clusterin, on amyloid fibril formation by lipid-free human apolipoprotein C-II (apoC-II) was investigated. Sub-stoichiometric levels of clusterin, derived from either plasma or semen, potently inhibit amyloid formation by apoC-II. Inhibition is dependent on apoC-II concentration, with more effective inhibition by clusterin observed at lower concentrations of apoC-II. The average sedimentation coefficient of apoC-II fibrils formed from apoC-II (0.3 mgÆmL)1) is reduced by coincubation with clusterin (10 lgÆmL)1). ...

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  • A clear difference in the enthalpy changes derived from spectroscopic and calorimetric measurements has recently been shown. The exact interpretation of this deviation varied from study to study, but it was generally attributed to the non-two-state transition and heat capacity change. Although the temperature-dependent thermodynamics of the duplex formation was often implied, systemic and extensive studies have been lacking in universally assigning the appropriate thermodynamic parameter sets.

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  • In many laboratories, the requirement of microtubule-associated proteins (MAPs) and the stabilization of microtubules for the elongation of neurites has been intensively investigated, with controversial results being obtained. We have observed that the neurite microtubules of Cath.a-differentiated (CAD) cells, a mouse brain derived cell, are highly dynamic structures, and so we analyzed several aspects of the cytoskeleton to investigate the molecu-lar causes of this phenomenon.

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  • Certain natural peptides and proteins of mammalian origin are able to bind and condense plasmid DNA, a prerequisite for the formation of transfec-tion-competent complexes that facilitate nonviral gene delivery. Here we have generated recombinant derivatives of the human high-mobility group (HMG) protein HMGB2 and investigated their potential as novel protein-based transfection reagents.

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  • Methylglyoxal is the most important intracellular glycation agent, formed nonenzymatically from triose phosphates during glycolysis in eukaryotic cells. Methylglyoxal-derived advanced glycation end-products are involved in neurodegenerative disorders (Alzheimer’s, Parkinson’s and familial amy-loidotic polyneurophathy) and in the clinical complications of diabetes.

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  • Patients with diabetes mellitus suffer from an increased incidence of complications including cardiovascular disease and cataracts; the mechanisms responsible for this are not fully understood. One characteristic of such complications is an accumulation of advanced glycation end-products formed by the adduction of glucose or species derived from glucose, such as low-molecular mass aldehydes, to proteins.

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  • As a derivative volume from Encyclopedia of Language and Linguistics 2nd edition, it comprises contributions from the foremost scholars of semantics in their various specializations and draws on 20+ years of development in the parent work in a compact and affordable format. Principally intended for tertiary level inquiry and research, this will be invaluable as a reference work for undergraduate and postgraduate students as well as academics inquiring into the study of meaning and meaning relations within languages.

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  • Carbonylation is one of the most important reactions leading to C-C bond formation. Direct synthesis of carbonyl compounds with CO gives rise to carboxylic acids and their derivatives, such as esters, amides, lactones, lactams etc. The process can be represented by the simple reactions of Scheme 5.1. In general, carbonylation proceeds via activation of a C-H or a C-X bond in the olefins and halides or alcohols, respectively, followed by COinsertion into the metal-carbon bond.

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  • This book describes many aspects of tissue culture models in an extensive manner.

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  • Bit Error Rate Degradation Caused by Random Tracking Errors 7.1 Introduction For coherent detection of digitally modulated signals, the receiver must be provided with accurate carrier phase and symbol timing estimates; these estimates are derived from the received signal itself by means of a synchronizer. The bit error rate (BER) performance under the assumption of perfect synchronization is well documented for various modulation formats [l-5].

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