Xem 1-20 trên 167 kết quả Development of obesity
  • Kate Flint points to “the development of the visualisation of experience” that continues through the nineteenth century; linking this experience to the “more permanent display of material” in museums and the “growing number of art exhibitions” (3). This development of a “visualisation of experience” is crucial for understanding the reception of classical antiquity during this period.

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  • For many years obesity in rodents has been known to be caused by a number of distinct mutations distributed through the genome. Most of these singlegene mutations cause both hyperphagia and diminished energy expenditure, suggesting a physiologic link between these two parameters of energy homeostasis. Identification of the ob gene mutation in genetically obese (ob/ob) mice represented a major breakthrough in the field. The ob/ob mouse develops severe obesity, insulin resistance, and hyperphagia, as well as efficient metabolism (e.g.

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  • Obesity and its associated disorders, including diabetes and cardiovascular disease, have now reached epidemic proportions in the Western world, resulting in dramatic increases in healthcare costs. Understanding the pro-cesses and metabolic perturbations that contribute to the expansion of adi-pose depots accompanying obesity is central to the development of appropriate therapeutic strategies.

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  • Apolipoprotein E is a polymorphic glycoprotein in humans with a molecu-lar mass of 34.5 kDa. It is a component of chylomicron remnants, very low density lipoprotein, low density lipoprotein and high density lipopro-tein, and is primarily responsible for maintaining plasma lipid homeostasis. In addition to these well-documented functions, recent studies in experi-mental mouse models, as well as population studies, show that apolipo-protein E also plays an important role in the development of obesity and insulin resistance. ...

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  • When you buy an existing business, you are assuming responsibility for an existing customer base. You are most concerned with the ability of the business to continue earning profits. The price you choose to pay for this business, therefore, is more related to the business' past profit earning record. One commonly accepted way of evaluating the business is projecting its profits for the next three years based on its last three years and discounting the present value (using present value tables) to this year.

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  • To track the dynamic of continuity and change since 1960, it’s conventional to start by looking at the film industry. As usually recounted, the indus- try’s fortunes over the period display a darkness-to-dawn arc that might satisfy a scriptwriter of epic inclinations.We now have several nuanced ver- sions of this story, so I’ll merely point out some major turning points. 1 The appendix provides a year-by-year chronology.

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  • Recently, Th17 cells were identified as a new subset of T helper cells unrelated to Th1 or Th2 cells. They are a subset of T helper cells characterized by IL-17 production, differentiated from naïve T cells in the presence of both transforming growth factor (TGF)-β and IL-6 in mice, and are implicated in the pathogenesis of experimental allergic encephalomyelitis (EAE) and collagen-induced arthritis (CIA) (Langrish et al. 2005).

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  • The market for organic food has increased considerably over the last decade due to consumer’s increasing awareness of both health and environmental issues (Soler et al., 2008). This growth in demand is expected to continue in the coming years, even though the situation differs from one country to another in term of type and quantities of production (Vindigni et al., 2002). The future of organic will, to a large extent, depend on consumer demand.

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  • Over the past few decades, life-threatening environmental concerns have surfaced in the developing world. Countrysides are coming under pressure from increasing numbers of farmers and the landless. Cities are filling with people, cars, and factories.

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  • According to Pierce-Eislen about 94% of the new construction is market rate while the remaining 6% is partially or fully affordable housing. Of the 10,217 units proposed, nearly 90% are market rate, 4% are mixed market rate and affordable and nearly 7% are fully affordable communities. Vacancy rates from county to county vary widely depending mostly on supply added to the market. Boulder/Broomfield reports vacancy at only 2.9% while Douglas and Jefferson Counties, also with limited new supply, reported vacancy rates of 4.1% and 3,7% respectively.

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  • The literature has pointed out to the relationship between obesity in youth and premature death due to endogenous causes of cardiac/metabolic origin. It is therefore fundamental to know how and when the risk factors for CMD begin to affect vascular function and structure, and particularly, how to detect them early in order to enable the development of truly primary preventive strategies.

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  • Using the CalSIM model, we predict changes in coverage in California as a result of the ACA. Take up of available coverage options in the model is based on a wide range of factors, including the pre-policy starting point, health status, household income, change in cost to purchase coverage, and English proficiency. For Medi-Cal, we assume that 61 percent of uninsured newly eligible individuals, and 10 percent of those who were previously eligible but not enrolled, enroll under our base scenario. is assumption is based on current Medi-Cal take up in the state.

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  • The Cancer Centers Program also recognizes that many high quality, cancer-relevant research projects are funded by other organizations such as the Department of Energy (DOE), Department of Defense (DOD), Department of Agriculture (DOA), the Center for Disease Control and Prevention (CDC), State Health Departments etc.

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  • Peroxyacyl nitrate (PAN) concentrations measured at a commercial site approximately 7 km north of the La Merced site were similar to those found in Los Angeles during the early 1970s. 16 PAN levels exceeded 30 ppb on five of the days sampled and exceeded 10 ppb on all but a few days of the study. 17 Although there is no air quality standard for PAN, high PAN concentrations are a good indicator of the organic oxidizing capacity of the urban air mass, since they are directly connected to organic peroxy radical formation and nitrogen dioxide (both ozone-forming precursors).

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  • From a general perspective, the verbal judgements referred to above have been obtained with one of two principal objectives in mind, objectives that have origi- nated and developed in traditionally differentiated pro- fessional fields: (1) that of environmental management, motivated by the need to solve a particular landscape problem, such as the identification of the landscape resources of a given location or to obtain some objecti- ve predictors of the evaluative judgements of users of a specific environment; and (2) that of a much more aca- demic character, geared to the develo...

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  • In this paper, we propose a new event recognition framework for consumer videos by leveraging a large amount of loosely labeled YouTube videos. Our work is based on the observation that a large amount of loosely labeled YouTube videos can be readily obtained by using keywords (also called tags) based search. However, the quality of YouTube videos is generally lower than con- sumer videos because YouTube videos are often down- sampled and compressed by the web server.

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  • At the same time that California is decreasing ECE funding, researchers throughout the nation are documenting the importance of the ECE industry as an engine of economic development. More than 58 states and localities have conducted analyses of the size and regional economic impact of the industry. Because of the way that ECE expenditures “ripple” through the local economy, this sector has been found to have an economic impact that rivals the impact of many of the industries that have traditionally received economic development dollars from local and state governments (Liu et al. 2004).

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  • The average total daily energy expenditure is higher in obese than lean individuals when measured at stable weight. However, energy expenditure falls as weight is lost, due in part to loss of lean body mass and to decreased sympathetic nerve activity. When reduced to near-normal weight and maintained there for a while, (some) obese individuals have lower energy expenditure than (some) lean individuals. There is also a tendency for those who will develop obesity as infants or children to have lower resting energy expenditure rates than those who remain lean.

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  • In 1996 Warner et al. (27) demonstrated that in the UK the prevalence of psychiatric morbidity in the postnatal period varied between 10-15%. With regards to postnatal depression, a systematic literature review carried out by Robertson et al. (28), found that the rates of both, first onset and severe depression were three times higher in the postnatal period than during other periods of women's lives. In a large proportion of women with postnatal depression, symptoms persist for at least a year postpartum.

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  • The regulations mandate that health plans provide enrollees with translated vital documents (for example, explanations of benefits) and ensure the availability of interpreter services at all points of patient contact, including clinical encounters (DrTango Inc. n.d.). Services must be provided at no cost to the enrollee. To guide the development of these services, plans must collect patient demographic data, including language information gathered through a patient survey. 3 Health plans also must monitor their language service programs to track plan and provider compli- ance.

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