Xem 1-20 trên 60 kết quả Developmental systems
  • During development, cells and tissues undergo dynamic changes in pattern and form that employ a wider range of physical mechanisms than at any other time during an organism’s life. Biological Physics of the Developing Embryo presents a framework within which physics can be used to analyze these biological phenomena. Written to be accessible to both biologists and physicists, major stages and components of biological development are introduced and then analyzed from the viewpoint of physics. The presentation of physical models requires no mathematics beyond basic calculus.

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  • Many families experience the challenges of caregiver depression and early childhood developmental delays. This tool kit provides information and resources for implementing depression screening within the early intervention system, strengthening cross-system collaborations, and implementing relationship-based care that focuses on the parent-child relationship in the early intervention and behavioral health systems.

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  • Discovery of a new chemical entity that exerts pharmacological effects for curing or treating diseases or relieving symptoms is only the first step in the drug developmental process. In the developmental cycle of a new drug, the delivery of a desired amount of a therapeutic agent to the target at a specific time or duration is as important as its discovery. In order to realize the optimal therapeutic outcomes, a delivery system should be designed to achieve the optimal drug concentration at a predetermined rate and at the desired location....

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  • Published: 27 May 2004 Genome Biology 2004, 5:227 The electronic version of this article is the complete one and can be found online at http://genomebiology.com/2004/5/6/227 © 2004 BioMed Central Ltd reviews Abstract Separation of cell types and developmental stages in the Arabidopsis root and subsequent expression profiling have yielded a valuable dataset that can be used to select candidate genes for detailed study and to start probing the complexities of gene regulation in plant development.

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  • Prion diseases are characterized by the accumulation of a pathogenic mis-folded form of a prion protein (PrP) encoded by the Prnpgene in humans. In the present study in zebrafish, two transcripts and the corresponding genes encoding prion proteins, PrP1 and PrP2, related to human PrP have been characterized with a relatively divergent deduced amino acid sequence, but a well preserved overall organization of structural prion pro-tein motifs.

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  • Molecular biology is the study of biology at a molecular level.[35] This field overlaps with other areas of biology, particularly with genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interrelationship of DNA, RNA, and protein synthesis and learning how these interactions are regulated.

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  • The concept of 'biotech' or 'biotechnology' encompasses a wide range of procedures (and history) for modifying living organisms according to human purposes — going back to domestication of animals, cultivation of plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies.

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  • Biotechnology (sometimes shortened to "biotech") is generally accepted as the use of living systems and organisms to develop or make useful products, or "any technological application that uses biological systems, living organisms or derivatives thereof, to make or modify products or processes for specific use" (UN Convention on Biological Diversity)[1] . For thousands of years, humankind has used biotechnology in agriculture, food production and medicine.[2] The term itself is largely believed to have been coined in 1919 by Hungarian engineer Karl Ereky.

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  • When an infection occurs, immune cells flock to the area and secrete large amounts of highly reactive chemicals to combat the invader. But, these inflammatory chemicals also attack normal tissue surrounding the infection and damage critical components of cells, including DNA. During chronic inflammation, DNA damage may lead to mutations or cell death and even to cancer and other diseases.

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  • The concept of tissue engineering is to regenerate target tissue by mimicking the developmental or regenerative process of that tissue. Thus, it can be considered an ideal therapeutic option for treating various tissue defects. Tissue engineering of skin, cartilage, and bone has already been shown both feasible and effective in several clinical studies, and its efficacy has attracted significant attention from both patients and doctors.

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  • Since Kant, philosophy has been obsessed with epistemological questions pertaining to the relationship between mind and world and human access to objects. In The Democracy of Objects Bryant proposes that we break with this tradition and once again initiate the project of ontology as first philosophy. Drawing on the object-oriented ontology of Graham Harman, as well as the thought Roy Bhaskar, Gilles Deleuze, Niklas Luhman, Aristotle, Jacques Lacan, Bruno Latour and the developmental systems theorists, Bryant develops a realist ontology that he calls “onticology”.

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  • Such a comprehensive model allows for the modeled deposition of submicrometer aerosols (nanosized particles and particulate matter sizes larger that nano to determine the total deposition as well as localized deposition of particles). The results are important, prospectively, since they may lead to a better understanding of the developmental respiratory physiology and the associated effects on children’s health response to environmental pollutants, or the medical outcome from inhalation therapy for infants and children from nanoparticlecontaining medicines.

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  • Providing the board conducted one, the previous year’s executive performance eval- uation most likely includes an action plan for the current year, with developmental goals for the executive. Include these in the evaluation; if not attended to, an excel- lent reason needs to be provided. Job description The executive job description should list major areas for which the executive is respon- sible. It’s essential that the board review this in preparation for the job evaluation, espe- cially if your board has never evaluated its director.

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  • Part of the total estimated eligible expenses must be financed from sources other than the Union grant. Applicants must indicate the sources and amounts of any other funding received or applied for in the same financial year for the implementation of the project or work programme concerned. The beneficiary shall supply evidence of the co-financing provided, either by way of own resources, or in the form of financial transfers from third parties, or in kind.

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  • Several acute lymphoblastic and myelogenous leukemias are correlated with alterations in the human mixed lineage leukemia protein-1 (MLL1) gene. MLL1 is a member of the evolutionarily conserved SET1 family of histone H3 lysine 4 (H3K4) methyltransferases, which are required for the regula-tion of distinct groups of developmentally regulated genes in metazoans.

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  • The authors examined the online construction of identity and sexuality in a large sample of conversations from monitored and unmonitored teen chat rooms. More than half of the 583 participants (identified by a distinct screen name) communicated identity information, most frequently gender. In this way, participants compensated for the text-based chat environment by providing information about themselves that would be visible and obvious in face-to-face communication.

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  • Ephrin receptor tyrosine kinase A3 (EphA3, EC is a member of a unique branch of the kinome in which downstream signaling occurs in both ligand- and receptor-expressing cells. Consequently, the ephrins and ephrin receptor tyrosine kinases often mediate processes involving cell–cell con-tact, including cellular adhesion or repulsion, developmental remodeling and neuronal mapping.

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  • Chapter 32 introduction to animal diversity. After completing this chapter, students will be able to: List the characteristics that combine to define animals; summarize key events of the Paleozoic, Mesozoic, and Cenozoic eras; compare the developmental differences between protostomes and deuterostomes.

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  • (BQ) Part 1 book "Netter's atlas of human embryology" presents the following contents: An overview of developmental events, processes and abnormalities, early embryonic development and the placenta, the nervous system, the cardiovascular system, the respiratory system.

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  • Department of Biochemistry and Molecular Biology and †The Genes and Development Graduate Program, The University of Texas M. D. Anderson Cancer Center, and ‡Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA. Correspondence: Georg Halder. E-mail: ghalder@mdanderson.org comment reviews Published: 25 March 2004 Genome Biology 2004, 5:216 The electronic version of this article is the complete one and can be found online at http://genomebiology.

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