Diazine

Ebook "Metalation of azines and diazines (Topics in Heterocyclic chemistry, Volume 31)" covers the reactions of pyridines, benzopyridines, and azapyridines with organolithiums and organomagnesiums. In this chapter also fundamental reaction pathways are outlined. The benzofused compounds quinolones and isoquinolines are treated, again their lithiation and magnesiation reactions.

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This review gives an overview of the application of guanidine and its salts in multicomponent reactions. It can act as a catalyst or solvent for multicomponent reactions or as a reagent for synthesis of substituted diazines, triazines, and macroheterocycles by multicomponent reactions.

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Heterocyclic 1,3-diazine nucleus is a valuable pharmacophore in the field of medicinal chemistry and exhibit a wide spectrum of biological activities. PharmMapper, a robust online tool used for establishing the target proteins based on reverse pharmacophore mapping.

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Introduction: Diazine and triazine herbicides are being widely used in the world. These herbicides inhibit the electron-transport system in the higher plants and thus suppress the photosynthesis, resulting in the herbicidal action. These compounds are also important as pollutants for crops, soil and groundwater [1, 2]. The attention is usually directed toward chronic toxicities of the herbicides [3].

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