(BQ) Part 2 book "Core topics in mechanical ventilation" presents the following contents: Nutrition in the mechanically ventilated patient, mechanical ventilation in asthma and chronic obstructive pulmonary disease, mechanical ventilation in patients with blast, burn and chest trauma injuries, ventilatory support - extreme solutions,...
(BQ) Part 1 book "Color atlas of oral diseases" presents the following contents: Normal anatomic variants, developmental anomalies, genetic diseases, mechanical injuries, oral lesions due to chemical agents, oral lesions due to smoking and heat, oral lesions due to drugs,..
Tham khảo sách 'erectile dysfunction – disease-associated mechanisms and novel insights into therapy edited by kenia pedrosa nunes', y tế - sức khoẻ, y học thường thức phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis...
(BQ) Part 2 book "Coronary artery disease - Assessment, surgery, prevention" presents the following contents: Coronary artery bypass surgery, surgical treatment in diffuse coronary artery disease, role and rationale for hybrid coronary artery revascularization, mechanical complications of myocardial infarction, prevention of coronary artery disease through diet,...
(BQ) Part 2 book "Dynamic echocardiography" presents the following contents: Coronary artery disease, mechanical complications of myocardial infarction, pericardial disease and intracardiac masses, myocardial diseases, heart failure filling pressures diastology, cardiac resynchr onization therapy, new technology, cases from around the world.
Non-alcoholic fatty liver disease (NAFLD), like
hepatitis C and HIV, is a disease of our generation.
Mostly unrecognized prior to 1980 and seldom taken
seriously until the past few years, NAFLD has seemingly
been thrust upon us unexpectantly like an
orphaned child left at our clinical bedside. In fact,
NAFLD was conceived during the industrial revolution,
which caused food to be processed differently,
provided that food more abundantly and made physical
work less demanding.
Over the past decade, there has been a vast explosion in new information
relating to the art and science of dermatology as well as fundamental cutaneous
biology. Furthermore, this information is no longer of interest only to
the small but growing specialty of dermatology. Scientists from a wide variety
of disciplines have come to recognize both the importance of skin in fundamental
biological processes and the broad implications of understanding
the pathogenesis of skin disease. As a result, there is now a multidisciplinary
and worldwide interest in the progress of dermatology....
Autoimmune disease represents a group of more than 60 different chronic autoimmune
diseases that affect approximately 6% of the population. It is the third major category of
illness in the United States and many industrialized countries, following heart disease
and cancer. Autoimmune diseases arise when one’s immune system actively targets and
destroys self tissue resulting in clinical disease. Common examples include Systemic
Lupus Erythematosus, Type 1 Diabetes, Rheumatoid Arthritis and Multiple Sclerosis.
Tham khảo sách 'allergic diseases – highlights in the clinic, mechanisms and treatment edited by celso pereira', y tế - sức khoẻ, y học thường thức phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả
Harrison's Internal Medicine Chapter 114. Molecular Mechanisms of Microbial Pathogenesis
Molecular Mechanisms of Microbial Pathogenesis: Introduction
Over the past three decades, molecular studies of the pathogenesis of microorganisms have yielded an explosion of information about the various microbial and host molecules that contribute to the processes of infection and disease.
Encounters with Epithelial Cells
Over the past decade, many bacterial pathogens have been shown to enter epithelial cells (Fig. 114-2); the bacteria often use specialized surface structures that bind to receptors, with consequent internalization. However, the exact role and the importance of this process in infection and disease are not well defined for most of these pathogens. Bacterial entry into host epithelial cells is seen as a means for dissemination to adjacent or deeper tissues or as a route to sanctuary to avoid ingestion and killing by professional phagocytes.
On the initiative of the International Dental Federation, a meeting of consultants
was convened by the World Health Organization in 1964 to consider the
classification of diseases of the buccal cavity in relation to the impending Eighth
(1965) Revision of the International Classification of Diseases (ICD). It was
recognized that a manual and guide should be compiled to assist in the
application of the ICD to dentistry and stomatology. Accordingly, a text was
drafted and tested in four countries, then revised and published for general use.
Harrison's Internal Medicine Chapter 55. Immunologically Mediated Skin Diseases
Immunologically Mediated Skin Diseases: Introduction
A number of immunologically mediated skin diseases and immunologically mediated systemic disorders with cutaneous manifestations are now recognized as distinct entities with consistent clinical, histologic, and immunopathologic findings. Many of these disorders are due to autoimmune mechanisms.
Encounters with Phagocytes
Phagocytosis and Inflammation Phagocytosis of microbes is a major innate host defense that limits the growth and spread of pathogens. Phagocytes appear rapidly at sites of infection in conjunction with the initiation of inflammation. Ingestion of microbes by both tissue-fixed macrophages and migrating phagocytes probably accounts for the limited ability of most microbial agents to cause disease.
Many diseases are caused primarily by pathogens growing in tissue sites that are normally sterile. Pneumococcal pneumonia is mostly attributable to the growth of S. pneumoniae in the lung and the attendant host inflammatory response, although specific factors that enhance this process (e.g., pneumolysin) may be responsible for some of the pathogenic potential of the pneumococcus. Disease that follows bacteremia and invasion of the meninges by meningitisproducing bacteria such as N. meningitidis, H. influenzae, E.
Transmission to New Hosts
As part of the pathogenic process, most microbes are shed from the host, often in a form infectious for susceptible individuals. However, the rate of transmissibility may not necessarily be high, even if the disease is severe in the infected individual, as transmissibility and virulence are not linked traits.
Enteric pathogens have developed a variety of tactics to overcome host defenses. Understanding the virulence factors employed by these organisms is important in the diagnosis and treatment of clinical disease.
The number of microorganisms that must be ingested to cause disease varies considerably from species to species. For Shigella, enterohemorrhagic Escherichia coli, Giardia lamblia, or Entamoeba, as few as 10–100 bacteria or cysts can produce infection, while 105–108Vibrio cholerae organisms must be ingested orally to cause disease.
Over the past few decades the field of neurology has seen spectacular developments in diagnostic techniques, most vividly
exemplified by modern neuroimaging and molecular genetics. Although not always at the same speed this evolution has
gone hand in hand with an enlarging armentarium of effective therapies to treat neurological disease.