DNA metabolism

Xem 1-20 trên 35 kết quả DNA metabolism
  • (BQ) Part 2 book "Lehninger principles of biochemistry" presents the following contents: Bioenergetics and metabolism (principles of bioenergetics; glycolysis, gluconeogenesis, and the pentose phosphate pathway; the metabolism of glycogen in animals,...), information pathways (genes and chromosomes, DNA metabolism, RNA metabolism, protein metabolism,...).

    pdf639p thangnamvoiva3 28-06-2016 11 4   Download

  • Since the discovery of the DNA structure researchers have been highly interested in the molecular basis of genome inheritance. This book covers a wide range of aspects and issues related to the field of DNA replication. The association between genome replication, repair and recombination is also addressed, as well as summaries of recent work of the replication cycles of prokaryotic and eukaryotic viruses. The reader will gain an overview of our current understanding of DNA replication and related cellular processes, and useful resources for further reading....

    pdf312p camchuong_1 04-12-2012 20 3   Download

  • Polymerase Chain Reaction is widely held as one of the most important inventions of the 20th century in molecular biology. Small amounts of the genetic material can now be amplified to be able to a identify, manipulate DNA, detect infectious organisms, including the viruses that cause AIDS, hepatitis, tuberculosis, detect genetic variations, including mutations, in human genes and numerous other tasks.

    ppt62p zingzing09 24-04-2013 21 5   Download

  • Glofish is the first transgenic animal approved to be consumed by human in the USA  The insertion of different constructs of GFP into the fish genomes to give different green colors.The idea for recombinant DNA was first proposed by Peter Lobban, a graduate student of Prof. Dale Kaiser in the Biochemistry Department at Stanford University Medical School. The first publications describing the successful production and intracellular replication of recombinant DNA appeared in 1972 and 1973.

    ppt54p zingzing09 24-04-2013 37 4   Download

  • DNA helicases are molecularmotor enzymes that use the energy of NTP hydrolysis to separate transiently energetic-ally stable duplex DNA into single strands. They are there-fore essential in nearly all DNA metabolic transactions. They act as essential molecular tools for the cellular machinery. Since the discovery of the first DNA helicase in Escherichia coliin1976, several havebeen isolated fromboth prokaryotic and eukaryotic systems.

    pdf15p dell39 03-04-2013 24 2   Download

  • “Epigenetics” as introduced by ConradWaddington in 1946, is defined as a set of interactions between genes and the surrounding environment, which determines the phenotype or physical traits in an organism, (Murrell et al., 2005;Waddington, 1942). Initial research focused on genomic regions such as heterochromatin and euchromatin based on dense and relatively loose DNA packing, since these were known to contain inactive and active genes respectively, (Yasuhara et al., 2005).

    pdf218p yeutinh98 22-09-2012 28 9   Download

  • The production of free radicals (ROS) is an unavoidable consequence of life in an aerobic environment. Free radicals produced from the metabolic activities of oxygen attack biological membranes and lipoproteins via oxidation in a process called lipid perioxidation. This attack damages cells and lipids often in a chain reaction with carbon-based molecules such as polyunsaturated fatty acids (PUFA) in a reaction with molecular oxygen. This creates oxidative stress and damage to tissues. Free radicals also damage chromosomal DNA.

    pdf272p mnemosyne75 02-02-2013 31 9   Download

  • PLANT BIOLOGISTS MAY BE FORGIVEN for taking abiding satisfaction in the fact that Mendel’s classic studies on the role of heritable factors in development were carried out on a flowering plant: the garden pea. The heritable factors that Mendel discovered, which control such characters as flower color, flower position, pod shape, stem length, seed color, and seed shape, came to be called genes. Genes are the DNA sequences that encode the RNA molecules directly involved in making the enzymes and structural proteins of the cell.

    pdf30p anhphuonggl 11-04-2013 20 6   Download

  • NA helicases are ubiquitous molecular motor proteins which harness the chemical free energy of ATPhydrolysis to catalyze the unwinding of energetically stable duplex DNA, and thus play important roles in nearly all aspects of nucleic acid metabolism, including replication, repair, recombina-tion, and transcription. They break the hydrogen bonds between the duplex helix and move unidirectionally along the bound strand. All helicases are also translocases and DNA-dependentATPases.Most contain conserved helicase motifs that act as an engine to power DNA unwinding. ...

    pdf14p dell39 03-04-2013 13 3   Download

  • DNA of prokaryotes is in a nonequilibrium structural state, characterized as ÔactiveÕ DNA supercoiling. Alterations in this state a€ect many life processes and a homeostatic control of DNA supercoiling has been suggested [Menzel, R. & Gellert, M. (1983) Cell 34, 105±113]. We here report on a new method for quantifying homeostatic control of the high-energy state of in vivo DNA. The method involves making small perturbation in the expression of topoisomerase I, and measuring the e€ect on DNA supercoiling of a reporter plasmid and on the expression of DNA gyrase....

    pdf8p system191 01-06-2013 10 3   Download

  • (BQ) Part 1 book "The big picture: Medical biochemistry" presents the following contents: Amino acids and proteins, carbohydrates, lipids, nucleosides, nucleotides, DNA, and RNA; integrated usmle style questions and answer, enzymes and amino acid protein metabolism, carbohydrate metabolism, lipid metabolism, membranes, DNA/RNA function and protein synthesis.

    pdf116p thangnamvoiva2 23-06-2016 12 3   Download

  • (BQ) Part 2 book "Lippincott's illustrated Q&A review of biochemistry" presents the following contents: Biochemical compounds, protein structure and function; DNA structure, replication and repair; RNA synthesis; protein synthesis, protein synthesis, molecular medicine and techniques, energy metabolism overview,...

    pdf116p thangnamvoiva3 28-06-2016 10 3   Download

  • Adequate transport of large proteins that function in the nucleus is indis-pensable for cognate molecular events within this organelle. Selective pro-tein import into the nucleus requires nuclear localization signals (NLS) that are recognized by importin receptors in the cytoplasm.

    pdf15p mobifone23 21-01-2013 17 2   Download

  • Replication protein A (RPA) complex has been shown, using bothin vivo and in vitro approaches, to be required for most aspects of eukaryotic DNA metabolism: replication, repair, telomere maintenance and homolo-gous recombination.

    pdf20p vinaphone15 27-02-2013 23 2   Download

  • Enhancer of rudimentary (ER) is a small protein that has a unique amino acid sequence and structure. Its highly conserved gene has been found in all eukaryotic kingdoms with the exception of fungi. ER was proposed to be involved in the metabolism of pyrimidines and was reported to act as a transcriptional repressor in a cell type-specific manner.

    pdf14p inspiron33 23-03-2013 18 2   Download

  • Cellular functions are ultimately linked to metabolic fluxes brought about by thousands of chemical reactions and transport processes. The synthesisof theunderlying enzymes and membrane transporters causes the cell a certaineffort of energyandexternal resources.Considering that those cells should have had a selection advantage during natural evo-lution that enabled them to fulfil vital functions (such as growth, defence against toxic compounds, repair of DNA alterations, etc.)

    pdf18p dell39 03-04-2013 14 2   Download

  • Mitochondrial DNA (mtDNA) deletion mutations accumulate with age in tissues of a variety of species. Although the relatively low calculated abundance of these deletion mutations in whole tissue homogenates led some investigators to suggest that these mutations do not have any physiological impact, their focal and segmental accumulation suggests that they can, and do, accumulate to levels sufficient to affect the metabolism of a tissue.

    pdf6p research12 01-06-2013 10 2   Download

  • A severe challenge to the idea that mitochondrial DNA mutations play a major role in the aging process in mammals is that clear loss-of-function mutations accumulate only to very low levels (under 1% of total) in almost any tissue, even by very old age. Their accumulation is punctate: some cells become nearly devoid of wild-type mitochondrial DNA and exhibit no activity for the partly mitochondrially encoded enzyme cytochrome c oxidase. Such cells accumulate in number with aging, suggesting that they survive indefinitely, which is itself paradoxical....

    pdf7p research12 01-06-2013 10 2   Download

  • (BQ) Part 1 book "Microbiology demystified" presents the following contents: The world of the microorganism, the chemical elements of microorganisms, observing microorganisms, prokaryotic cells and eukaryotic cells, the chemical metabolism, microbial growth and controlling microbial growth, microbial genetics, recombinant DNA technology.

    pdf162p thangnamvoiva2 23-06-2016 12 2   Download

  • The book updated material on Infrared Spectroscopy and Nuclear Magnetic Resonance of amines, aldehydes/ketones, and carboxylic acid derivatives. Updated information on DNA sequencing (the process of determination of the precise sequence of nucleotides within a DNA molecule) and DNA synthesis.

    pdf465p bautroibinhyen20 06-03-2017 3 2   Download


Đồng bộ tài khoản