For over 50 years, interest has been expressed in optimizing drug therapy through
delivery system design. For many years this revolved around incorporating drugs
into erodible or inert polymers, which then acted as platforms for controlled release,
an approach that has been well reviewed in the literature.
This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery.
Discovery of a new chemical entity that exerts pharmacological effects for
curing or treating diseases or relieving symptoms is only the first step in
the drug developmental process. In the developmental cycle of a new
drug, the delivery of a desired amount of a therapeutic agent to the target
at a specific time or duration is as important as its discovery. In order
to realize the optimal therapeutic outcomes, a delivery system should
be designed to achieve the optimal drug concentration at a predetermined
rate and at the desired location....
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Combination of Polymer Technology and Carbon Nanotube Array for the Development of an Effective Drug Delivery System at Cellular Leve
Despite the advances in the development of new drugs, a drug may never reach the
target organ, or it may be difficult to achieve the necessary level of drug in the
body. Large doses can result in serious side effects, and can harm normal cells and
organs as well as diseased cells. Hence controlled release and the targeting of delivery
systems must evolve in parallel to drug research.
There continues to be an explosion of research on issues
of pharmacologic relevance to primary eye care delivery.
New ophthalmic formulations are being developed, new
diagnostic methods introduced,and new medications and
delivery systems are available that were unheard of a
decade ago. It is important that these new concepts be
introduced to students and practitioners alike.
Minimally Invasive Surgery represents the future of many types of medical interventions such
as keyhole neurosurgey or transluminal endoscopic surgery. These procedures involve insertion
of surgical instruments such as needles and endoscopes into human body through small
incision/ body cavity for biopsy and drug delivery.
Ovarian cancer is the leading cause of death among women with gynecologic malignancies in the United States. Advanced ovarian cancers are difficult to cure with the current available chemotherapy, which has many associated systemic side effects. Doxorubicin is one such chemotherapeutic agent that can cause cardiotoxicity. Novel methods of delivering chemotherapy without significant side effects are therefore of critical need.
Special challenges that must be taken into account in
managing asthma in children in the first 5 years of life
include difficulties with diagnosis, the efficacy and safety of
drugs and drug delivery systems, and the lack of data on
new therapies. Patients in this age group are often
managed by pediatricians who are routinely faced with a
wide variety of issues related to childhood diseases.
Therefore, for the convenience of readers this Executive
Summary extracts sections of the report that pertain to
diagnosis and management of asthma in children 5 years
The development and deployment of NEMS and MEMS are critical to the U.S. economy and society because nano- and microtechnologies will lead to major breakthroughs in information technology and computers, medicine and health, manufacturing and transportation, power and energy systems, and avionics and national security.
Scientists who dedicate their research activity to biomaterials pass through the typical
dichotomy that often characterizes the basic research.
On one side is the wish of exploring new frontiers of chemistry, physics, biology,
medicine, pharmaceutics and all other disciplines to which biomaterials can be
applied. Constantly improving of scientific knowledge would feed the freedom of
attempting new strategies for producing materials with always tailored and improved
In chapter nineteen, Kaneda et al. develop a
hemagglutinating virus of Japan envelope (HVJ-E) vector using inactivated Sendai
virus, as a pseudovirion for gene and drug delivery. They evaluate the anti-tumor
effects of HVJ-E itself on mouse and human melanoma in animal models, and also the
enhancement of anti-tumor effects of HVJ-E containing IL-12 gene.
The rapidly increasing number of applications for microemulsions has kept this relatively old topic still at the top point of research themes. This book provides an assessment of some issues influencing the characteristics and performance of the microemulsions, as well as their main types of applications. In chapter 1 a short introduction about the background, various aspects and applications of microemulsions is given. In Part 2 some experimental and modeling investigations on microstructure and phase behavior of these systems have been discussed. ...
Figure 3 Cumulative release GCV from the scleral plugs of PLA-70,000 and PLA-5000 (whose content ratio was 80:20) containing 25% of GCV. The values shown are mean Æ SD. The duration of GCV release was prolonged further compared with the plug made of PLGA (75/25)-121,000. Abbreviations: GCV, ganciclovir; PLA, polylactic acid; PLGA, polyglycolic acid. Source: From Ref. 4.
weight: 5000) at weight ratios of 80/20. These plugs included 25% GCV.
The marketing of agricultural commodities in the United States is done by a private enterprise
system. It involves millions of individual decisions (to grow, to buy, to sell, to store, to ship) on
the part of farmers, marketing men, and consumers.
Agricultural marketing is a huge national and international operation. The marketing system is
intricate. It is sensitive to many economic and international developments, which include
strikes, weather, political upheavals and related factors that affect marketing activities.
Pharmaceutical packaging technology structured to meet the needs of the global market, this volume provides an assessment of a wide range of issues. It covers the entire supply chain from conversion of raw materials into packaging materials and then assembled into product packs. Integrating information from many drug delivery systems, the author discusses testing and evaluation and emphasizes traceability and the need to for additional safeguards.
Các nhà xuất bản cung cấp giảm giá về cuốn sách này khi đặt hàng với số lượng lớn. Để biết thêm thông tin, viết thư để tiêu thụ đặc biệt / Tiếp thị chuyên nghiệp tại địa chỉ trụ sở chính ở trên. C g Bản quyền năm 2003 của Marcel Dekker, Inc. Không cuốn sách này cũng không phải bất kỳ
các thuật toán: những tác động về liều lượng. J Clin Pharm 2001; 26:213-223. Brook I, Ledney GD. Quinolone điều trị trong themanagement nhiễm trùng sau khi chiếu xạ. Crit Rev Microbiol năm 1992; 18:235-246. Brooks RG. Nghiên cứu tiền cứu của Candida endophthalmitis ở bệnh nhân nhập viện với candidemia