For over 50 years, interest has been expressed in optimizing drug therapy through
delivery system design. For many years this revolved around incorporating drugs
into erodible or inert polymers, which then acted as platforms for controlled release,
an approach that has been well reviewed in the literature.
Porous metal organic framework nanoscale carriers as a potential platform for drug
delivery and imaging, In the domain of health, one important challenge is the efficient delivery of drugs in the body using non-toxic nanocarriers. Most of the existing carrier materials show poor drug loading and or rapid release of the proportion of the drug that is simply adsorbed at the external surface of the nanocarrier.
Discovery of a new chemical entity that exerts pharmacological effects for
curing or treating diseases or relieving symptoms is only the first step in
the drug developmental process. In the developmental cycle of a new
drug, the delivery of a desired amount of a therapeutic agent to the target
at a specific time or duration is as important as its discovery. In order
to realize the optimal therapeutic outcomes, a delivery system should
be designed to achieve the optimal drug concentration at a predetermined
rate and at the desired location....
Products of nanotechnology are expected to revolutionize
modern medicine, as evidenced by recent scientific advances
and global initiatives to support nanotechnology and nanomedicine
research. The field of drug delivery is a direct beneficiary
of these advancements. Due to their versatility in
targeting tissues, accessing deep molecular targets, and controlling
drug release, nanoparticles are helping address challenges
to face the delivery of modern, as well as conventional
This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery.
With contributions from many of the world's leading scientists in the field of dendritic research and development, Dendrimers and Other Dendritic Polymers provides a comprehensive review of this rapidly expanding and exciting new field of polymer science. Of interest to academia and industry alike, this book covers the synthesis, characterization, unique properties, potential for novel applications and technical challenges associated with these polymers.
Despite massive efforts in drug discovery fueled by combinatory
chemistry, recombinant DNA technology, and highthroughput
screening, surprisingly few molecules make it
through the drug development process. While the reasons
are debated, it is certain that many new chemical entities
(NCEs) suffer from recurring problems that hinder development—
low water solubility, instability, or inadequate
pharmacokinetics. An estimated 43% of NCEs are poorly
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Investigation of utilization of nanosuspension formulation to enhance exposure of 1,3dicyclohexylurea in rats: Preparation for PK/PD study via subcutaneous route of nanosuspension drug delivery
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice...
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Combination of Polymer Technology and Carbon Nanotube Array for the Development of an Effective Drug Delivery System at Cellular Leve
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: CD134 as target for specific drug delivery to T cells in adjuvant arthritis...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:"Tuberculosis chemotherapy: current drug delivery approaches...
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Development of PEGylated PLGA nanoparticle for controlled and sustained drug delivery in cystic fibrosis
Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Metabolically stable bradykinin B2 receptor agonists enhance transvascular drug delivery into malignant brain tumors by increasing drug half-life
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Beyond platinum: synthesis, characterization, and in vitro toxicity of Cu(II)-releasing polymer nanoparticles for potential use as a drug delivery vector
T he premise for this book was to provide a single volume covering the principles
of transdermal and topical drug delivery and how these are put into practice during
the development of new products. We have divided the book into two sections to
deal with each of these perspectives and hope that their contents will appeal equally
to readers based in academia and industry. We also hope that it will help each of
these readers better understand the perspective of the other and therefore aid communication