In a crunch, when interviewing an eyewitness, Dragnet’s Sgt. Joe Friday
would implore, ‘‘Just the facts, ma’am, just the facts.’’ Our textbook, Just
the Facts in Emergency Medicine, aims to provide just that for emergency
physicians who are studying for either the written board (re)certification
examination in emergency medicine or the in-training written examination
The prognosis for individuals with liver cancer is frequently poor. Cancers include those which have metastasized to the liver from elsewhere, reflecting advanced stage disease where cure is rarely possible. Similarly, primary liver cancer frequently complicates chronic liver disease, which further limits therapeutic options. Despite these dismal facts, there are signs that change is imminent. Not only have imaging modalities and surgical techniques improved, but preventive strategies and medical therapies show promise.
Advances in our understanding of the molecular principles underlining both health and disease
has revealed the existence of many regulatory polypeptides of significant medical potential. The
fact that such polypeptides are produced naturally within the body only in minute quantities
initially precluded their large-scale medical application. The development in the 1970s of the
twin techniques of genetic engineering and hybridoma technology marked the birth of the
modern biotech era.
Acne — it’s not exactly a subject that you like to talk about
every day. At social events, you do your best to conceal
it under makeup (although if you’re a man, makeup is usually
not a realistic option). For kids, acne is more than just a stage of
adolescence — it’s the pits! In fact, acne can be a problem for
people of any age. Even newborns and seniors can develop acne! Americans currently spend more than $4 billion a year on skin
treatments, nearly $100 million of which goes toward nonprescription
acne medications alone.
The aim of this chapter is to summarize and evaluate the different
mechanisms and catabolic mediators involved in cancer cachexia and ageing
sarcopenia since they may represent targets for future promising clinical
investigations. Cancer cachexia is a syndrome characterized by a marked weight
loss, anorexia, asthenia and anemia. In fact, many patients who die with advanced
cancer suffer from cachexia. The degree of cachexia is inversely correlated
with the survival time of the patient and it always implies a poor prognosis.
A wealth of neurological textbooks, journals, and papers are available
today. The student of clinical neuroscience is therefore faced with a large
number of unrelated facts that can be very difficult to remember and
apply. In neurology, one of the most difficult tasks is knowing how to
reach the correct diagnosis by differentiating it from the other possibilities,
so that the patient can receive the appropriate treatment for the
Acute-care clinicians are well aware of the alphabetical
“ABC” (airway, breathing, circulation)
directive of resuscitation. This term has been
widely disseminated through programs such as
Advanced Trauma Life Support (ATLS) and Advanced
Cardiac Life Support (ACLS). In fact,
both courses have contributed significantly to
improving awareness of resuscitation priorities
required in managing patients rendered critically
ill from trauma or cardiac events.
The benefit-to-risk ratio of blood products needs constant
evaluation. Blood products, as therapeutic agents,
have had the test of time but lack the evidence we expect
from other medicinals. Blood, an organ, is used as
a pharmaceutical agent by the medical profession, due to
the achievements in collection, processing, banking, and
distribution. The fact that the most common risk of blood
transfusion isblood delivery error supports the notion that
blood is handled as a pharmaceutical agent.
Few of us are ever going to become professional researchers,
but all of us will find times when research is indispensable to
our lives. Whether you're looking for information about a
car's safety record, a community's schools, or a company's
stock, you'll need to know how to gather, sort, and track the
facts and opinions available to you.
The global cost of communicable diseases is expected to rise. SARS has
put the world on alert. We have now Avian Flu on the watch. Recognizing
the global nature of threats posed by new and re-emerging infectious diseases
and the fact that many recent occurrences originated in the Asia Pacific
regions, there has been an increased interest in learning and knowing
about disease surveillance and monitoring progresses made in these regions.
Such knowledge and awareness is necessary to reduce conflict, discomfort,
tension and uneasiness in future negotiations and global cooperation....
Over the past six decades, tourism has experienced continued expansion and diversification
becoming one of the largest and fastest growing economic sectors in the world. Many new
destinations have emerged alongside the traditional ones of Europe and North America. In
the next years an increase of travelling is expected, and the number of related infections will
also be higher (http://www.unwto.org/facts/menu.html). Rickettsioses are an important
chapter in the field of travel medicine.
The research recommends that
marketers think about dollars instead of percentages. If restaurants hold onto their mark-
ups, but experience a 50% drop in volume, they are worse off than if they were to drop
prices and keep a strong volume. The vast majority of restaurants have gotten away
from a straight three-time markup across an entire list. Additionally, restaurants need to
recognize the fact that certain staples, such as Opus One or Dom Perignon, act as
barometers diners generally know how much the wine costs, and look to these
selections as benchmarks on list pricing.
In Latin America, the rates of institutionalization
of older people range from 1% to 4%. Institutional
care is no longer considered unacceptable for an
older person but is seen as an alternative for
families. The government-sponsored asilos, large
institutions resembling the early English workhouses,
have been converted into smaller facilities
with professional staff from many disciplines.
Other homes are operated by religious communities
of immigrant origin.
Given its speed, lower costs and powerful targeting abilities, the online world
represents a highly cost-effective media platform for reaching customers and
potential customers. Marketers are taking advantage of these opportunities to
expand their business, devoting a steadily growing portion of their budgets to
online marketing initiatives.
In a survey1
of marketing executives, eMarketer finds that while offline media
spends, including newspapers, magazines, television and radio, steadily decrease,
Internet marketing spends are increasing 20 to 30 percent each year.
The discovery of the hormone insulin by Frederick Banting and colleagues in the early
1920’s is one of the greatest medical breakthroughs and has saved millions of lives over the
years. The significance of the discovery is underscored by the fact that type 1 diabetics still
have an absolute requirement for daily injections of insulin to live. Clearly, today’s insulin
treatments have attained levels of sophistication that have greatly improved clinical out‐
All of us like to think that our actions and reactions are a result of logical thought processes, but the fact is
that suggestion influences our thinking a great deal more than logic. Consciously or unconsciously, our
feelings about almost everything are largely molded by ready-made opinions and attitudes fostered by our
mass methods of communication. We cannot buy a bar of soap or a filtered cigarette without paying tribute to
the impact of suggestion. Right or wrong, most of us place more confidence in what "they" say than we do in
our own powers of reason.
The agency believes that NCAP has helped make significant safety improvements by providing
consumers with independent information that they can use in their purchasing decisions. This
information has helped drive consumer demand for safety and manufacturers have responded by
building vehicles that exceed Federal motor vehicle safety standards, thereby contributing to
NHTSA’s mission of reducing death and injuries from motor vehicle crashes.
Recent developments/efforts to understand aspects of the brain function at the subneural
level are discussed. MicroTubules (MTs), protein polymers constructing the
cytoskeleton, participate in a wide variety of dynamical processes in the cell. Of special
interest to us is the MTs participation in bioinformation processes such as learning
and memory, by possessing a well-known binary error-correcting code [K1(13, 26, 5)]
with 64 words. In fact, MTs and DNA/RNA are unique cell structures that possess
a code system.
Helicobacter pylori, which persistently colonizes the stomachs of ~50% of the world's human population, is the main risk factor for peptic ulceration (Chap. 287) as well as for gastric adenocarcinoma and gastric MALT (mucosa-associated lymphoid tissue) lymphoma (Chap. 87). Treatment for H. pylori has revolutionized the management of peptic ulcer disease, providing a permanent cure in many cases. The prevention of H. pylori colonization could potentially represent primary prevention of gastric malignancy and peptic ulceration.
Early attempts to look at the link between air pollution and wildlife focused mainly on the so-
called "charismatic megafauna", ie on large and "colourful" species of animals. In fact, the most
widely affected species - in terms of both number of species suffering damage from air pollution
and also sensitivity of individual species to pollution - are amongst the lower life forms. In
particular, lichens, bryophytes, fungi, and soft-bodied aquatic invertebrates are likely to be at