This print-based, self-study course provides public health and other healthcare professionals with basic epidemiology principles, concepts, and procedures used in the surveillance and investigation of health-related events. This resource contains key features and applications of descriptive and analytic epidemiology, an in-depth study of public health surveillance, and a step-by-step description of outbreak investigations.
Endocrinology: Basic and Clinical Principles, Second
Edition aims to provide a comprehensive knowledge
base for the applied and clinical science of
endocrinology. The challenge in its presentation was
to produce a volume that was timely, provided integration
of basic science with physiologic and clinical principles,
and yet was limited to 500 pages. This length
makes the volume suitable as a text; and the timeliness
we have striven for allows the book to serve as an offthe-
Diseases of the nervous system number in the hundreds and are too
numerous and varied to be learned in their entirety. Hence the common
practice of subdividing them into categories—traumatic, vascular, neoplastic,
infective, metabolic, degenerative, congenital, and so forth. In
our textbook, Principles of Neurology, we describe the various categories
of neurologic disease and the main diseases that constitute each
The goal of cancer treatment is first to eradicate the cancer. If this primary goal cannot be accomplished, the goal of cancer treatment shifts to palliation, the amelioration of symptoms, and preservation of quality of life while striving to extend life. The dictum primum non nocere is not the guiding principle of cancer therapy. When cure of cancer is possible, cancer treatments may be undertaken despite the certainty of severe and perhaps life-threatening toxicities.
Epidemiology Patients receive, on average, 10 different drugs during each hospitalization. The sicker the patient, the more drugs are given, and there is a corresponding increase in the likelihood of adverse drug reactions. When 15 drugs are given, the probability is 40%. Retrospective analyses of ambulatory patients have revealed adverse drug effects in 20%.
Applied Radiological Anatomy for Medical Students is the definitive atlas of
human anatomy, utilizing the complete range of imaging modalities
to describe normal anatomy and radiological findings.
Initial chapters describe all imaging techniques and introduce the
principles of image interpretation. These are followed by
comprehensive sections on each antomical region.
Hundreds of high-quality radiographs, MRI, CT and ultrasound
images are included, complemented by concise, focused text.
Advances in our understanding of the molecular principles underlining both health and disease
has revealed the existence of many regulatory polypeptides of significant medical potential. The
fact that such polypeptides are produced naturally within the body only in minute quantities
initially precluded their large-scale medical application. The development in the 1970s of the
twin techniques of genetic engineering and hybridoma technology marked the birth of the
modern biotech era.
Our main purpose in editing this book is to provide the health care practitioner
with general clinical practical guidelines regarding the use of pediatric
cardiovascular drugs. We also intend to provide an overview of basic pediatric
cardiovascular principles. We realize the need for a pocket reference handbook that
is tailored to meet the daily challenges of practitioners that care for pediatric
Vascular ultrasound is a speciality in its own right
and vascular surgeons are becoming increasingly
dependent on the skills of vascular sonographers for
the investigation of patients suffering from peripheral
vascular disease. This book aims to provide an
understanding of the principles and practice of vascular
This book has been written to enable health care workers to understand the principles of
managing an acute medical emergency safely and effectively.To achieve this aim it provides
a structured approach to medical emergencies, describing relevant pathophysiology
that will also help to explain physical signs and the rationale behind treatment.The first
edition of this manual (written by Terry Wardle) has undergone significant modification
directed by the working group and also, in particular, candidates from the first
Recent advances in clinical proteomics have propelled us into an exciting period of discovery of
new cancer biomarkers, although the available proteomic technologies have their limitations. The
principles of proteomic technology require stringent guidelines for the collection of clinical material,
the application of analytical techniques, and for our interpretation of the data.
In this review, we present an overview of the serum tumor markers in current use.
The present second edition of the Color Atlas of Pharmacology goes to print six years
after the first edition. Numerous revisions were needed, highlighting the dramatic
continuing progress in the drug sciences. In particular, it appeared necessary to include
novel therapeutic principles, such as the inhibitors of platelet aggregation
from the group of integrin GPIIB/IIIA antagonists, the inhibitors of viral protease, or
the non-nucleoside inhibitors of reverse transcriptase. Moreover, the re-evaluation
and expanded use of conventional drugs, e.g.
Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal disorders in the
Western world. In recent years, there have been many developments in the field of GERD. At least, all these
developments have helped to find new diagnostic procedures and different treatment concepts. As well
known, GERD affects patients quality of life and leads to a significant economic burden on society. Therefore,
all further investigations should primary aim in an improvement of patients daily life.
The underlying principle in managing diabetes
has undergone several important changes over the
last two decades. Diabetes was once believed to
be a disease with inevitable microvascular and
macrovascular complications. Current approaches
to management, however, recognize the benefit
of maintaining tight glycemic control and addressing
associated metabolic disorders.
This compact and concise monograph lays a foundation for the understanding of normal cardiovascular function. Students welcome the book as a practical partner or alternative to a more mechanistically oriented approach or an encyclopedic physiology text. Especially clear explanations, ample illustrations, clinical cases and problems, and chapter-opening learning objectives provide guidance for self-directed learning and help fill the gap in many of today's abbreviated physiology blocks. A focus on well-established cardiovascular principles reflects recent, widely accepted research....
The inevitability of a disease sounds a clarion for its prevention, or at least its control.
Understanding its pathophysiology is essential to that process. For osteoarthritis,
preconceived notions and mythology must be transcended to allow identification of its
essentials. The first step was to establish a scientific basis for its recognition. Sorting
associated phenomenon allowed identification of those which are non-diagnostic, and
one major finding which is pathognomonic: the joint osteophyte.
Other peculiarities of the sites are
that the systems are updated frequently, that advertising is not a source for funding and that the
Publication of personal information is dependent from a personal written agreement, for example, for
the member list of AIG. The principles of the Health-On-the-Net-Foundation (HON) are implemented
by both websites.
Theoretical analysis and computational modeling are important tools for
characterizing what nervous systems do, determining how they function,
and understanding why they operate in particular ways. Neuroscience
encompasses approaches ranging from molecular and cellular studies to
human psychophysics and psychology. Theoretical neuroscience encourages
cross-talk among these sub-disciplines by constructing compact representations
of what has been learned, building bridges between different
levels of description, and identifying unifying concepts and principles.
The process of informed consent is a well established medical practice which has
its roots in ethics and law. The requirement to obtain informed consent is based on
the ethical principle of self determination and is strengthened in application by
both statutory and case law. As a general rule, with few exceptions, and endoscopist
is required to obtain informed consent prior to the performance of any endoscopic
Before endoscopes for colon examination achieved the
remarkable technological progress that we see today,
there was a long period when rigid proctosigmoidoscopes
were used for examination of the distal half of the
sigmoid colon and rectum.
Intracolonic photography of colonic mucosa, using
a modification of the gastrocamera described as “sigmoidocamera”
or “colonocamera,” was briefly used in
Japan. Diagnosis was by examining pictures of the
colonic mucosa obtained with the colonocamera.